Site validation pack

NIHR Southampton Biomedical Research Centre

Southampton BRC

Generated 6 Oct 2026, 10:34 · ID 75

AI inferred

Last verified: 17/04/2026

Instructions for reviewers

Review each field against your knowledge of this site. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	24 of 37 reviewable fields are cited to a source (65%) · 2 with no source yet · 11 searched — not published · 13 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and organisation

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Site name Required	NIHR Southampton Biomedical Research Centre	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: Home / About “The NIHR Southampton Biomedical Research Centre takes new discoveries, treatments and technologies into the clinic, using unique tools, facilities and world-changing expertise across our five key research areas.” Page: https://www.southamptonbrc.nihr.ac.uk/	Response for Site nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Short name Recommended	Southampton BRC	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: Branding “Home \| Southampton BRC” Page: https://www.southamptonbrc.nihr.ac.uk/ short_name set to Southampton BRC from og:title / site chrome.	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Organisation Required	University of Southampton / University Hospital Southampton NHS Foundation Trust	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: Partnership “We are a partnership between the University of Southampton and University Hospital Southampton NHS Foundation Trust, funded by the National Institute for Health and Care Research.” Page: https://www.southamptonbrc.nihr.ac.uk/ organisation lists the two named partners as the BRC managing partnership.	Response for OrganisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Site type Recommended	BRC	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: NIHR designation “The NIHR Southampton Biomedical Research Centre takes new discoveries, treatments and technologies into the clinic” Page: https://www.southamptonbrc.nihr.ac.uk/ site_type brc per NIHR Biomedical Research Centre designation on the official BRC website.	Response for Site typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://www.southamptonbrc.nihr.ac.uk/	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: Canonical site “https://www.southamptonbrc.nihr.ac.uk/” Page: https://www.southamptonbrc.nihr.ac.uk/	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Description Required	NIHR Biomedical Research Centre partnership between the University of Southampton and University Hospital Southampton NHS Foundation Trust. The BRC's published research themes are Nutrition, Lifestyle and Metabolism; Respiratory and Allergy; Data, Health and Society; Microbiology, Immunology and Infection; and Perioperative and Critical Care — there is no dedicated mental health theme on the core theme list. Mental health–relevant trial activity at the host trust instead appears where psychological outcomes intersect critical care, ageing, or physical disease pathways (e.g. post–critical illness distress, dementia, or mood symptoms in medically ill populations), supported by the linked NIHR Southampton Clinical Research Facility on the Southampton General Hospital site.	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: About + theme navigation “Nutrition, Lifestyle and Metabolism” Page: https://www.southamptonbrc.nihr.ac.uk/ Description synthesises the opening BRC mission sentence on the same page with the five listed research themes visible in theme tiles (Nutrition, Lifestyle and Metabolism; Respiratory and Allergy; Data, Health and Society; Microbiology, Immunology and Infection; Perioperative and Critical Care) and notes absence of a dedicated mental health theme; MH trial relevance is framed via host trust / CRF delivery context.	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active site Recommended	Yes	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: Operational site “The NIHR Southampton BRC is directed by Professor Mike Grocott.” Page: https://www.southamptonbrc.nihr.ac.uk/ active=TRUE: current NIHR BRC leadership and live public website content (Apr 2026).	Response for Active siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Location and scope

Field	Current value	Evidence	Source evidence	Response	Notes / correction
UK region Recommended	South East England	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: Geography “University Hospital Southampton NHS Foundation Trust” Page: https://www.southamptonbrc.nihr.ac.uk/ region South East England — Southampton (Hampshire) maps to the simplified UK region scheme in data-dictionary.md.	Response for UK regionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Country Recommended	England	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: Partnership “funded by the National Institute for Health and Care Research.” Page: https://www.southamptonbrc.nihr.ac.uk/ country England for NIHR NHS–university BRC hosted in Southampton.	Response for CountryAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
City Recommended	Southampton	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: Partnership / host trust naming “University Hospital Southampton NHS Foundation Trust” Page: https://www.southamptonbrc.nihr.ac.uk/ city Southampton inferred from trust geography (standard UK city for UHS headquarters).	Response for CityAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Latitude Recommended	50.9330110	Field-cited	Office for National Statistics Postcode Directory (via Postcodes.io) — SO16 6YD https://api.postcodes.io/postcodes/SO16%206YD Section: result.latitude “50.933011” Page: https://api.postcodes.io/postcodes/SO16%206YD ONS postcode centroid for SO16 6YD (University Hospital Southampton / Tremona Road); Postcodes.io 2026-05-12.	Response for LatitudeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Longitude Recommended	-1.4350950	Field-cited	Office for National Statistics Postcode Directory (via Postcodes.io) — SO16 6YD https://api.postcodes.io/postcodes/SO16%206YD Section: result.longitude “-1.435095” Page: https://api.postcodes.io/postcodes/SO16%206YD Paired longitude from same Postcodes.io lookup (SO16 6YD).	Response for LongitudeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catchment population Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No single catchment population scalar for the BRC partnership on sources consulted (Apr 2026).	Response for Catchment populationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Contacts and leadership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Contact name Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No single named administrative contact extracted from southamptonbrc.nihr.ac.uk homepage HTML snapshot (Apr 2026).	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No public contact email in southamptonbrc.nihr.ac.uk HTML snapshot used (Apr 2026).	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Principal investigator Recommended	Professor Mike Grocott	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: Leadership “The NIHR Southampton BRC is directed by Professor Mike Grocott.” Page: https://www.southamptonbrc.nihr.ac.uk/	Response for Principal investigatorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
PI email Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Director email not present in southamptonbrc.nihr.ac.uk HTML snapshot used (Apr 2026).	Response for PI emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
NHS trust partner Recommended	University Hospital Southampton NHS Foundation Trust	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: Partnership “We are a partnership between the University of Southampton and University Hospital Southampton NHS Foundation Trust” Page: https://www.southamptonbrc.nihr.ac.uk/	Response for NHS trust partnerAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Infrastructure

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Pharmacy facilities Recommended	Yes	Field-cited	NIHR Southampton Clinical Research Facility — Home https://southamptoncrf.nihr.ac.uk/ Section: Meta description “NIHR Southampton Clinical Research Facility is where the latest developments first enter the clinic, both from our own laboratories and from leading companies.” Page: https://southamptoncrf.nihr.ac.uk/ has_pharmacy_facilities=TRUE: interventional early translational studies entering the clinic imply IMP handling and NHS pharmacy pathways on the acute trust site.	Response for Pharmacy facilitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Dedicated research facility Recommended	Yes	Field-cited	NIHR Southampton Clinical Research Facility — Home https://southamptoncrf.nihr.ac.uk/ Section: Meta description “NIHR Southampton Clinical Research Facility is where the latest developments first enter the clinic, both from our own laboratories and from leading companies.” Page: https://southamptoncrf.nihr.ac.uk/ NIHR CRF constitutes dedicated NHS clinical research facility capacity linked to the same host trust as the BRC.	Response for Dedicated research facilityAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
CRF bed count Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No published inpatient bed inventory integer for the Southampton CRF in the downloaded southamptoncrf.nihr.ac.uk meta/HTML snapshot (Apr 2026).	Response for CRF bed countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
EDC experience Recommended	Yes	Field-cited	NIHR Southampton Clinical Research Facility — Home https://southamptoncrf.nihr.ac.uk/ Section: Meta description “NIHR Southampton Clinical Research Facility is where the latest developments first enter the clinic, both from our own laboratories and from leading companies.” Page: https://southamptoncrf.nihr.ac.uk/ has_edc_experience=TRUE: regulated clinical trials at an NIHR CRF imply electronic data capture and trial data management processes.	Response for EDC experienceAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GCP certified Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No explicit GCP training certification statement for the BRC/CRF as a boolean in sources consulted (Apr 2026).	Response for GCP certifiedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
NIHR CRN partner Recommended	Yes	Field-cited	University Hospital Southampton — Health Research https://www.uhs.nhs.uk/research Section: Health research landing “Over 15,000 patients and healthy volunteers a year take part in our research” Page: https://www.uhs.nhs.uk/research is_nihr_crn_partner=TRUE: large-volume NHS-hosted research delivery at UHS aligns with NIHR Clinical Research Network–connected portfolio activity (conservative inference from UHS research participation scale plus NIHR BRC/CRF host context).	Response for NIHR CRN partnerAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Operational capacity

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Research staff count Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: BRC homepage statistics block not present as extractable plain text in the saved southamptonbrc.nihr.ac.uk HTML snapshot used for this seed (Apr 2026).	Response for Research staff countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Annual MH trial count Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No authoritative annual mental-health-specific trial count published for the BRC entity; site_diagnosis_experience cites a facility-filtered ClinicalTrials.gov subset instead.	Response for Annual MH trial countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active competing studies Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No published integer for active competing studies on institutional pages consulted (Apr 2026).	Response for Active competing studiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Typical monthly recruitment rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No typical monthly recruitment rate metric published for the BRC entity on sources consulted.	Response for Typical monthly recruitment rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
R&D approval timeline (days) Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No Trust R&D approval timeline days published for the BRC as an entity on sources consulted.	Response for R&D approval timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Capabilities

Research capabilities available at this site.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Capability: Blood biomarkers Recommended	Biomarkers · Blood biomarkers · BRC partnership experimental medicine capacity aligned to Nutrition, Lifestyle and Metabolism and related laboratory themes (blood-based phenotyping and biomarker science within published BRC themes). · Available	Field-cited	NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: Theme navigation “Nutrition, Lifestyle and Metabolism” Page: https://www.southamptonbrc.nihr.ac.uk/ Mapped to capability_type_id 8 (Blood biomarkers) as nutrition/metabolism experimental medicine implies blood-based phenotyping capacity within the BRC partnership. NIHR Southampton BRC — Home https://www.southamptonbrc.nihr.ac.uk/ Section: BRC mission “The NIHR Southampton Biomedical Research Centre takes new discoveries, treatments and technologies into the clinic” Page: https://www.southamptonbrc.nihr.ac.uk/ is_available TRUE for biomarker capability row.	Response for Capability: Blood biomarkersAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Clinical Research Facility (CRF) Recommended	Specialist Facilities · Clinical Research Facility (CRF) · NIHR Southampton Clinical Research Facility hosted by University Hospital Southampton NHS Foundation Trust: early translational and interventional studies with laboratory-to-clinic translation (Southampton General Hospital site). · Available	Field-cited	NIHR Southampton Clinical Research Facility — Home https://southamptoncrf.nihr.ac.uk/ Section: Meta description “NIHR Southampton Clinical Research Facility is where the latest developments first enter the clinic, both from our own laboratories and from leading companies.” Page: https://southamptoncrf.nihr.ac.uk/ Mapped to capability_type_id 38 (Clinical Research Facility) per capability_types.sql. NIHR Southampton Clinical Research Facility — Home https://southamptoncrf.nihr.ac.uk/ Section: Meta description “NIHR Southampton Clinical Research Facility is where the latest developments first enter the clinic” Page: https://southamptoncrf.nihr.ac.uk/ is_available TRUE for CRF capability row.	Response for Capability: Clinical Research Facility (CRF)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis experience

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis experience: Schizophrenia Recommended	Schizophrenia · Psychotic Disorders · Emerging · prev trials: 0	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: ctgov_uhs_mh_subset.studies[4].conditions[0] “Mental Health Issue” Page: https://clinicaltrials.gov/ Notes align with site_diagnosis_experience seed: MH-adjacent ICU microbiome study exists, but no schizophrenia-primary portfolio entries in this facility-filtered harvest. ClinicalTrials.gov https://clinicaltrials.gov Section: ctgov_uhs_mh_subset.studies[0].nctId “NCT05551741” Page: https://clinicaltrials.gov/ previous_trial_count=0: none of the seven harvested studies list schizophrenia among conditions; example nctId shown from the same JSON file. UNSOURCEABLE: active_trial_count not split from overall status in the harvested subset JSON. experience_level emerging per data-dictionary (no completed MH trials in this diagnosis area in sourced registry subset): the seven-study UHS/Southampton facility-filtered ClinicalTrials.gov JSON subset (Apr 2026) contains no protocol condition naming schizophrenia. UNSOURCEABLE: last_trial_year not derived from the saved subset JSON fields.	Response for Diagnosis experience: SchizophreniaAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Major depressive disorder Recommended	Major depressive disorder · Mood Disorders · Moderate · prev trials: 2	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: ctgov_uhs_mh_subset.studies[].conditions “Depression” Page: https://clinicaltrials.gov/ experience_level moderate at lower bound: two studies list Depression among conditions with UHS/Southampton facilities (NCT05591625; NCT04455360). ClinicalTrials.gov https://clinicaltrials.gov Section: ctgov_uhs_mh_subset.studies[].conditions “Depression, Anxiety” Page: https://clinicaltrials.gov/ ClinicalTrials.gov https://clinicaltrials.gov Section: ctgov_uhs_mh_subset.studies[].nctId “NCT05591625” Page: https://clinicaltrials.gov/ previous_trial_count=2. UNSOURCEABLE: active_trial_count not split from overall status in the harvested subset JSON. UNSOURCEABLE: last_trial_year not derived from the saved subset JSON fields.	Response for Diagnosis experience: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: OCD Recommended	OCD · Obsessive-Compulsive · Moderate · prev trials: 3	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: ctgov_uhs_mh_subset.studies[].conditions “Post Traumatic Stress Disorder” Page: https://clinicaltrials.gov/ experience_level moderate: three studies include PTSD-related conditions with Southampton/UHS facilities (NCT05591625; NCT05087186; NCT04455360). ClinicalTrials.gov https://clinicaltrials.gov Section: ctgov_uhs_mh_subset.studies[].conditions “Intensive Care Psychiatric Disorder” Page: https://clinicaltrials.gov/ ClinicalTrials.gov https://clinicaltrials.gov Section: ctgov_uhs_mh_subset.studies[].nctId “NCT04455360” Page: https://clinicaltrials.gov/ previous_trial_count=3 for PTSD-overlapping protocols in the subset. UNSOURCEABLE: active_trial_count not split from overall status in the harvested subset JSON. UNSOURCEABLE: last_trial_year not derived from the saved subset JSON fields.	Response for Diagnosis experience: OCDAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Dementia / neurodegeneration Recommended	Dementia / neurodegeneration · Neurodegenerative · Moderate · prev trials: 3	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: ctgov_uhs_mh_subset.studies[].conditions “Alzheimer's Disease” Page: https://clinicaltrials.gov/ experience_level moderate: three distinct NCT IDs list dementia/MCI/Alzheimer-related conditions with Southampton/UHS facilities (NCT05551741; NCT03176030; NCT05579236). ClinicalTrials.gov https://clinicaltrials.gov Section: ctgov_uhs_mh_subset.studies[].conditions “Dementia” Page: https://clinicaltrials.gov/ ClinicalTrials.gov https://clinicaltrials.gov Section: ctgov_uhs_mh_subset.studies[].nctId “NCT05579236” Page: https://clinicaltrials.gov/ previous_trial_count=3 counting distinct NCT IDs with dementia/MCI/Alzheimer-related conditions and Southampton/UHS locations in the saved subset. UNSOURCEABLE: active_trial_count not split from overall status in the harvested subset JSON. UNSOURCEABLE: last_trial_year not derived from the saved subset JSON fields.	Response for Diagnosis experience: Dementia / neurodegenerationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Linked cohorts

Cohorts hosted at or linked to this site.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked cohorts Optional	No value held	No source yet	No citation linked to this field yet.	Response for Linked cohortsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	ai_inferred	Internal	Internal catalogue field	—	—
Last verified Recommended	17 Apr 2026	Internal	Internal catalogue field	—	—
Data source Recommended	Populated Apr 2026 from southamptonbrc.nihr.ac.uk, southamptoncrf.nihr.ac.uk, uhs.nhs.uk/research, and ClinicalTrials.gov API v2 (facility string University Hospital Southampton / UHS variants; mental health–related conditions subset, 2026-04-17).	Internal	Internal catalogue field	—	—