Site validation pack

NIHR Manchester Clinical Research Facility

Manchester CRF

Generated 6 Oct 2026, 10:35 · ID 61

AI inferred

Last verified: 16/04/2026

Instructions for reviewers

Review each field against your knowledge of this site. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
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Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	28 of 41 reviewable fields are cited to a source (68%) · 2 with no source yet · 11 searched — not published · 10 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and organisation

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Site name Required	NIHR Manchester Clinical Research Facility	Field-cited	NIHR Manchester Clinical Research Facility — Home https://manchestercrf.nihr.ac.uk/ Section: Footer “The NIHR Manchester Clinical Research Facility (CRF) is the largest and most comprehensive NIHR CRF in the UK, enabling cutting-edge clinical research across a diverse range of clinical areas.” Page: https://manchestercrf.nihr.ac.uk/	Response for Site nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Short name Recommended	Manchester CRF	Field-cited	NIHR Manchester Clinical Research Facility — About https://manchestercrf.nihr.ac.uk/about/ Section: About — heading “Manchester Clinical Research Facility (CRF) is the largest and most comprehensive NIHR CRF in the UK.” Page: https://manchestercrf.nihr.ac.uk/about/ Short label Manchester CRF taken from the (CRF) parenthetical in this heading.	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Organisation Required	Manchester University NHS Foundation Trust	Field-cited	NIHR Manchester Clinical Research Facility — About https://manchestercrf.nihr.ac.uk/about/ Section: Our role in the GM Research and Innovation community “We are hosted by Manchester University NHS Foundation Trust, one of the largest acute Trusts in the UK.” Page: https://manchestercrf.nihr.ac.uk/about/	Response for OrganisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Site type Recommended	CRF	Field-cited	NIHR Manchester Clinical Research Facility — About https://manchestercrf.nihr.ac.uk/about/ Section: About — heading “Manchester Clinical Research Facility (CRF) is the largest and most comprehensive NIHR CRF in the UK.” Page: https://manchestercrf.nihr.ac.uk/about/ Public entity is an NIHR Clinical Research Facility; site_type=crf per data dictionary.	Response for Site typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://manchestercrf.nihr.ac.uk/	Field-cited	NIHR Manchester Clinical Research Facility — Home https://manchestercrf.nihr.ac.uk/ Section: Canonical link “https://manchestercrf.nihr.ac.uk/” Page: https://manchestercrf.nihr.ac.uk/	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Description Required	Largest and most comprehensive NIHR Clinical Research Facility in the UK, hosted by Manchester University NHS Foundation Trust and operating across six NHS teaching hospital sites across Greater Manchester with more than 50 research beds, 24/7 inpatient and outpatient research services (including children), and Phase I-II experimental medicine capacity.	Field-cited	NIHR Manchester Clinical Research Facility — Home https://manchestercrf.nihr.ac.uk/ Section: Footer + About “The NIHR Manchester Clinical Research Facility (CRF) is the largest and most comprehensive NIHR CRF in the UK, enabling cutting-edge clinical research across a diverse range of clinical areas.” Page: https://manchestercrf.nihr.ac.uk/ Combined with About page statements on six NHS sites, >50 beds, and 24/7 services to form the seed description text.	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active site Recommended	Yes	Field-cited	NIHR Manchester Clinical Research Facility — Home https://manchestercrf.nihr.ac.uk/ Section: Home — news-style content / site maintenance “NIHR Manchester Clinical Research Facility Annual Report 24-25” Page: https://manchestercrf.nihr.ac.uk/ Active NIHR site with current content and dated annual reporting; active=TRUE.	Response for Active siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Location and scope

Field	Current value	Evidence	Source evidence	Response	Notes / correction
UK region Recommended	North West England	Field-cited	NIHR Manchester Clinical Research Facility — About https://manchestercrf.nihr.ac.uk/about/ Section: About “We operate in six world-class facilities based at NHS teaching hospitals across Greater Manchester (GM):” Page: https://manchestercrf.nihr.ac.uk/about/ Greater Manchester maps to controlled vocabulary North West England.	Response for UK regionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Country Recommended	England	Field-cited	NIHR Manchester Clinical Research Facility — About https://manchestercrf.nihr.ac.uk/about/ Section: About “We are hosted by Manchester University NHS Foundation Trust, one of the largest acute Trusts in the UK.” Page: https://manchestercrf.nihr.ac.uk/about/ England for NHS NIHR facility.	Response for CountryAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
City Recommended	Manchester	Field-cited	NIHR Manchester Clinical Research Facility — About https://manchestercrf.nihr.ac.uk/about/ Section: About — hospital list “Manchester Royal Infirmary” Page: https://manchestercrf.nihr.ac.uk/about/ Primary city label Manchester from named Manchester hospitals / GM city region.	Response for CityAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Latitude Recommended	53.4624520	Field-cited	Office for National Statistics Postcode Directory (via Postcodes.io) — M13 9WL https://api.postcodes.io/postcodes/M13%209WL Section: result.latitude “53.462452” Page: https://api.postcodes.io/postcodes/M13%209WL ONS centroid for M13 9WL; Postcodes.io 2026-05-12.	Response for LatitudeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Longitude Recommended	-2.2277090	Field-cited	Office for National Statistics Postcode Directory (via Postcodes.io) — M13 9WL https://api.postcodes.io/postcodes/M13%209WL Section: result.longitude “-2.227709” Page: https://api.postcodes.io/postcodes/M13%209WL Paired longitude from same Postcodes.io lookup (M13 9WL).	Response for LongitudeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catchment population Recommended	2,800,000	Field-cited	NIHR Manchester Clinical Research Facility — About https://manchestercrf.nihr.ac.uk/about/ Section: Our role in the GM Research and Innovation community “Health Innovation Manchester (HInM), the system that brings together the Greater Manchester City Region's civic authorities, industry, universities and NHS organisations to work collaborative on improving the lives of its 2.8 million population.” Page: https://manchestercrf.nihr.ac.uk/about/ Used 2.8 million Greater Manchester city-region population as catchment_population (approximate public geography figure).	Response for Catchment populationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Contacts and leadership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Contact name Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Header lists email/phone only; no named primary contact field populated.	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	rsm-mcrf@mft.nhs.uk	Field-cited	NIHR Manchester Clinical Research Facility — Home https://manchestercrf.nihr.ac.uk/ Section: Header contact “rsm-mcrf@mft.nhs.uk” Page: https://manchestercrf.nihr.ac.uk/	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Principal investigator Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No lead PI for the CRF stated on reviewed home/about/facilities pages.	Response for Principal investigatorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
PI email Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No PI email on reviewed Manchester CRF overview pages.	Response for PI emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
NHS trust partner Recommended	Manchester University NHS Foundation Trust	Field-cited	NIHR Manchester Clinical Research Facility — About https://manchestercrf.nihr.ac.uk/about/ Section: Hosting statement “We are hosted by Manchester University NHS Foundation Trust, one of the largest acute Trusts in the UK.” Page: https://manchestercrf.nihr.ac.uk/about/	Response for NHS trust partnerAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Infrastructure

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Pharmacy facilities Recommended	No	Not published	Searched — not published UNSOURCEABLE as TRUE: Reviewed Manchester CRF home, about, and facilities HTML downloads; no explicit on-site pharmacy/dispensary statement for the CRF comparable to other verified site records. Conservative default FALSE.	Response for Pharmacy facilitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Dedicated research facility Recommended	Yes	Field-cited	NIHR Manchester Clinical Research Facility — About https://manchestercrf.nihr.ac.uk/about/ Section: About “Our Manchester CRF approach to clinical research facilities provides dedicated buildings, equipment, and laboratories for experimental research.” Page: https://manchestercrf.nihr.ac.uk/about/	Response for Dedicated research facilityAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
CRF bed count Recommended	51	Field-cited	NIHR Manchester Clinical Research Facility — About https://manchestercrf.nihr.ac.uk/about/ Section: About “We provide 24-hour, 7-day inpatient and outpatient research services, including those for children and infants, with more than 50 research beds and over 20 outpatient consultation rooms across GM.” Page: https://manchestercrf.nihr.ac.uk/about/ Integer set to 51 as the smallest whole number consistent with 'more than 50'.	Response for CRF bed countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
EDC experience Recommended	No	Not published	Searched — not published UNSOURCEABLE as TRUE: No Epic/EDC/ePRO statement found in downloaded Manchester CRF pages; conservative default FALSE.	Response for EDC experienceAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GCP certified Recommended	No	Not published	Searched — not published UNSOURCEABLE as TRUE: No explicit ICH-GCP certification statement for the CRF on downloaded pages; default FALSE.	Response for GCP certifiedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
NIHR CRN partner Recommended	Yes	Field-cited	NIHR Manchester Clinical Research Facility — Home https://manchestercrf.nihr.ac.uk/ Section: Footer “The NIHR Manchester Clinical Research Facility (CRF) is the largest and most comprehensive NIHR CRF in the UK” Page: https://manchestercrf.nihr.ac.uk/ NIHR Clinical Research Facility is part of NIHR research infrastructure; is_nihr_crn_partner=TRUE.	Response for NIHR CRN partnerAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Operational capacity

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Research staff count Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No numeric research staffing count on downloaded Manchester CRF pages.	Response for Research staff countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Annual MH trial count Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No annual mental-health trial throughput figure on facility pages; registry queries support diagnosis experience rows but not an annual site total.	Response for Annual MH trial countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active competing studies Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No current competing-studies count on downloaded Manchester CRF pages.	Response for Active competing studiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Typical monthly recruitment rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No monthly recruitment rate on downloaded Manchester CRF pages.	Response for Typical monthly recruitment rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
R&D approval timeline (days) Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No R&D approval timeline in days on downloaded Manchester CRF pages.	Response for R&D approval timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Capabilities

Research capabilities available at this site.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Capability: Structural MRI Recommended	Imaging · Structural MRI · MRI Scanner listed under Manchester CRF at Manchester Royal Infirmary (adult and paediatric studies). · Available	Field-cited	NIHR Manchester Clinical Research Facility — Facilities https://manchestercrf.nihr.ac.uk/facilities/ Section: Manchester CRF at Manchester Royal Infirmary (MRI) “MRI Scanner” Page: https://manchestercrf.nihr.ac.uk/facilities/	Response for Capability: Structural MRIAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Overnight facility Recommended	Specialist Facilities · Overnight facility · Outpatient, day-case and overnight ward areas (e.g. Christie site); 24-hour 7-day inpatient and outpatient research services across GM. · Available	Field-cited	NIHR Manchester Clinical Research Facility — Facilities https://manchestercrf.nihr.ac.uk/facilities/ Section: Manchester CRF at The Christie Hospital “Outpatient, day-case and overnight ward areas, supporting patient recruitment, screening assessments and delivery of all phases of complex oncology studies including complex immunotherapy and Immune Effector Cell/CAR-T therapy.” Page: https://manchestercrf.nihr.ac.uk/facilities/ Overnight ward capability; combined with About page 24/7 inpatient/outpatient services.	Response for Capability: Overnight facilityAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Point-of-care testing (POCT) Recommended	Biomarkers · Point-of-care testing (POCT) · Point-of-care equipment throughout Manchester CRF at MRI. · Available	Field-cited	NIHR Manchester Clinical Research Facility — Facilities https://manchestercrf.nihr.ac.uk/facilities/ Section: Manchester CRF at Manchester Royal Infirmary (MRI) “Point-of-care equipment throughout” Page: https://manchestercrf.nihr.ac.uk/facilities/	Response for Capability: Point-of-care testing (POCT)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Clinical Research Facility (CRF) Recommended	Specialist Facilities · Clinical Research Facility (CRF) · NIHR Clinical Research Facility operating across six NHS teaching hospital sites in Greater Manchester with more than 50 research beds and consolidated experimental medicine assets. · Available	Field-cited	NIHR Manchester Clinical Research Facility — About https://manchestercrf.nihr.ac.uk/about/ Section: About — facilities list + beds “We operate in six world-class facilities based at NHS teaching hospitals across Greater Manchester (GM):” Page: https://manchestercrf.nihr.ac.uk/about/	Response for Capability: Clinical Research Facility (CRF)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Phase 1 unit Recommended	Trial Methodology · Phase 1 unit · Phase I and II complex and high-intensity clinical research studies at Manchester Royal Infirmary CRF. · Available	Field-cited	NIHR Manchester Clinical Research Facility — Facilities https://manchestercrf.nihr.ac.uk/facilities/ Section: Manchester CRF at Manchester Royal Infirmary (MRI) “particularly Phase I and II complex and high-intensity clinical research studies” Page: https://manchestercrf.nihr.ac.uk/facilities/	Response for Capability: Phase 1 unitAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis experience

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis experience: Major depressive disorder Recommended	Major depressive disorder · Mood Disorders · Extensive · prev trials: 6	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 studies export “overallStatus” Page: https://clinicaltrials.gov/ Query: Manchester University NHS Foundation Trust AND (Schizophrenia OR Depression OR Bipolar OR Anxiety OR Psychosis OR Mental Health OR PTSD OR OCD). Location filter on study text for Manchester-area tokens. Deduped studies to one primary MH bucket per NCTId; Major depressive disorder family count=6 completed-classified studies => experience_level extensive (>=5). previous_trial_count=6. Export saved locally.	Response for Diagnosis experience: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Treatment-resistant depression Recommended	Treatment-resistant depression · Mood Disorders · Moderate · prev trials: 2	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 studies export Page: https://clinicaltrials.gov/ Treatment-resistant depression keyword family count=2 => moderate (2-4).	Response for Diagnosis experience: Treatment-resistant depressionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Post-partum depression Recommended	Post-partum depression · Mood Disorders · Some · prev trials: 1	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 studies export Page: https://clinicaltrials.gov/ Perinatal/postpartum keyword family count=1 => some.	Response for Diagnosis experience: Post-partum depressionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Generalised anxiety disorder Recommended	Generalised anxiety disorder · Anxiety Disorders · Moderate · prev trials: 2	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 studies export Page: https://clinicaltrials.gov/ Generalised anxiety / GAD keyword family count=2 => moderate.	Response for Diagnosis experience: Generalised anxiety disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Social anxiety disorder Recommended	Social anxiety disorder · Anxiety Disorders · Some · prev trials: 1	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 studies export Page: https://clinicaltrials.gov/ Social anxiety keyword family count=1 => some.	Response for Diagnosis experience: Social anxiety disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Linked cohorts

Cohorts hosted at or linked to this site.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked cohorts Optional	No value held	No source yet	No citation linked to this field yet.	Response for Linked cohortsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	ai_inferred	Internal	Internal catalogue field	—	—
Last verified Recommended	16 Apr 2026	Internal	Internal catalogue field	—	—
Data source Recommended	Populated Apr 2026 from manchestercrf.nihr.ac.uk (home, about, facilities pages) and ClinicalTrials.gov API v2 export (query: Manchester University NHS Foundation Trust × mental health-related conditions, 2026-04-16).	Internal	Internal catalogue field	—	—