Site validation pack

NIHR Sheffield Clinical Research Facility

Sheffield CRF

Generated 6 Oct 2026, 10:34 · ID 60

AI inferred

Last verified: 16/04/2026

Instructions for reviewers

Review each field against your knowledge of this site. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
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Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	32 of 44 reviewable fields are cited to a source (73%) · 2 with no source yet · 10 searched — not published · 9 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and organisation

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Site name Required	NIHR Sheffield Clinical Research Facility	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Introductory paragraph “The NIHR Sheffield Clinical Research Facility (CRF) is situated in the centre of Sheffield” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities Full site name in seed matches the NIHR Sheffield Clinical Research Facility branding in this sentence.	Response for Site nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Short name Recommended	Sheffield CRF	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Body text “The NIHR Sheffield Clinical Research Facility (CRF) is situated in the centre of Sheffield” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities Short label Sheffield CRF taken from the (CRF) acronym in this sentence.	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Organisation Required	Sheffield Teaching Hospitals NHS Foundation Trust / University of Sheffield	Field-cited	NIHR Sheffield BRC — Collaborating facilities (NIHR Sheffield CRF) https://www.sheffieldbrc.nihr.ac.uk/about-us/collaborating-facilities/nihr-clinical-research-facility Section: Footer — Sheffield BRC hosting statement “hosted by Sheffield Teaching Hospitals NHS Foundation Trust in partnership with The University of Sheffield.” Page: https://www.sheffieldbrc.nihr.ac.uk/about-us/collaborating-facilities/nihr-clinical-research-facility Seed organisation string combines this hosting partnership with the CRF's Sheffield Teaching Hospitals campus context.	Response for OrganisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Site type Recommended	CRF	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Body text “The NIHR Sheffield Clinical Research Facility (CRF)” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities Public-facing entity is the NIHR Clinical Research Facility; site_type=crf per data-dictionary precedence (standalone CRF).	Response for Site typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://www.sheffield.crf.nihr.ac.uk/	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Canonical “https://www.sheffield.crf.nihr.ac.uk/” Page: https://www.sheffield.crf.nihr.ac.uk/	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Description Required	The NIHR Sheffield Clinical Research Facility (CRF) operates at the Royal Hallamshire Hospital and Northern General Hospital, providing dedicated space for commercial and academic clinical research including experimental medicine, overnight stays, and multi-disciplinary research nursing support across specialties relevant to mental health feasibility (including assessment rooms and dementia-friendly environments).	Field-cited	NIHR Sheffield BRC — Collaborating facilities (NIHR Sheffield CRF) https://www.sheffieldbrc.nihr.ac.uk/about-us/collaborating-facilities/nihr-clinical-research-facility Section: About “experienced in undertaking all types of commercial and academic sponsored clinical research” Page: https://www.sheffieldbrc.nihr.ac.uk/about-us/collaborating-facilities/nihr-clinical-research-facility Second source line for the commercial/academic clause in seed description text. NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Introductory paragraph “The Royal Hallamshire Hospital (RHH) and Northern General Hospital (NGH) CRFs provide a safe and welcoming environment for delivering clinical research studies. The NIHR Sheffield CRF supports adult research studies across a diverse range of health conditions.” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities Supplemented with commercial/academic and overnight context from Sheffield BRC page (quote: experienced in undertaking all types of commercial and academic sponsored clinical research; sheffieldbrc_collaborating_crf_2026-04-16.html); dementia-friendly reception (quote: Dementia-friendly reception area; sheffield_crf_rhh_2026-04-16.html).	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active site Recommended	Yes	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Operational context “delivering clinical research studies” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities Site content describes active delivery; active=TRUE.	Response for Active siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Location and scope

Field	Current value	Evidence	Source evidence	Response	Notes / correction
UK region Recommended	Yorkshire and the Humber	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Body text “situated in the centre of Sheffield” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities Sheffield maps to Yorkshire and the Humber in docs/data-dictionary.md UK Regions list.	Response for UK regionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Country Recommended	England	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Address block “Sheffield” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities/royal-hallamshire-hospital England for NHS England site; display_name on geocode JSON confirms England.	Response for CountryAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
City Recommended	Sheffield	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Address block “Sheffield” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities/royal-hallamshire-hospital	Response for CityAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Latitude Recommended	53.3786824	Field-cited	OpenStreetMap Nominatim — geocoding API response (Royal Hallamshire Hospital) https://nominatim.openstreetmap.org/ Section: API JSON “"lat":"53.3786824"” Page: https://nominatim.openstreetmap.org/ Coordinates taken from Nominatim search result for Royal Hallamshire Hospital, S10 2JF; stored as DECIMAL per schema.	Response for LatitudeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Longitude Recommended	-1.4931593	Field-cited	OpenStreetMap Nominatim — geocoding API response (Royal Hallamshire Hospital) https://nominatim.openstreetmap.org/ Section: API JSON “"lon":"-1.4931593"” Page: https://nominatim.openstreetmap.org/ Paired with latitude from the same Nominatim result.	Response for LongitudeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catchment population Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: CRF is not a population catchment organisation; no catchment figure on accessed CRF or BRC pages.	Response for Catchment populationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Contacts and leadership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Contact name Recommended	RHH CRF Reception Team	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Useful information “Our friendly RHH CRF Reception Team can be contacted on 0114 271 3339.” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities/royal-hallamshire-hospital Stored as RHH CRF Reception Team for telephone-first enquiries.	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no single primary contact email for the whole CRF on the accessed home/our facilities/RHH pages; partial emails appear only in tour-request context on the same page.	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Principal investigator Recommended	Professor Chris Newman	Field-cited	NIHR Sheffield BRC — Collaborating facilities (NIHR Sheffield CRF) https://www.sheffieldbrc.nihr.ac.uk/about-us/collaborating-facilities/nihr-clinical-research-facility Section: Team “Professor Chris Newman Director of the NIHR Sheffield Clinical Research Facility” Page: https://www.sheffieldbrc.nihr.ac.uk/about-us/collaborating-facilities/nihr-clinical-research-facility	Response for Principal investigatorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
PI email Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Director email not listed on accessed Sheffield BRC collaborating facilities page or CRF landing pages in this batch.	Response for PI emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
NHS trust partner Recommended	Sheffield Teaching Hospitals NHS Foundation Trust	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Body text “Sheffield Teaching Hospitals NHS Foundation Trust's central campus” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities/royal-hallamshire-hospital Normalised to full trust name Sheffield Teaching Hospitals NHS Foundation Trust.	Response for NHS trust partnerAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Infrastructure

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Pharmacy facilities Recommended	No	Not published	Searched — not published UNSOURCEABLE as TRUE: accessed CRF pages describe a sample handling laboratory but do not state IMP storage/dispensing per NHS SPS pharmacy criteria; set FALSE.	Response for Pharmacy facilitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Dedicated research facility Recommended	Yes	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Facilities list “Our facilities at NIHR Sheffield CRF at RHH The NIHR Sheffield Clinical Research Facility (CRF) located at the Royal Hallamshire Hospital (RHH) site offers:” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities/royal-hallamshire-hospital Dedicated CRF floor space with listed clinical research rooms.	Response for Dedicated research facilityAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
CRF bed count Recommended	6	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Facilities list “2 single bedrooms a fully equipped 4 bedded bay area with nurses' station” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities/royal-hallamshire-hospital Integer 6 sums two single bedrooms plus four bay beds at RHH CRF; other site (NGH) not added to avoid double-counting without published NGH bed list.	Response for CRF bed countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
EDC experience Recommended	No	Not published	Searched — not published UNSOURCEABLE as TRUE: no Epic/EDC statement in downloaded CRF HTML; left FALSE per schema default.	Response for EDC experienceAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GCP certified Recommended	No	Not published	Searched — not published UNSOURCEABLE as TRUE: no explicit ICH-GCP training statement on accessed facility pages; left FALSE.	Response for GCP certifiedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
NIHR CRN partner Recommended	Yes	Field-cited	NIHR Sheffield BRC — Collaborating facilities (NIHR Sheffield CRF) https://www.sheffieldbrc.nihr.ac.uk/about-us/collaborating-facilities/nihr-clinical-research-facility Section: About “The Clinical Research Facility (CRF) is funded by the NIHR to accelerate the delivery of experimental medicine clinical research” Page: https://www.sheffieldbrc.nihr.ac.uk/about-us/collaborating-facilities/nihr-clinical-research-facility NIHR-funded NHS-facing CRF integrated with NIHR research delivery ecosystem; is_nihr_crn_partner=TRUE.	Response for NIHR CRN partnerAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Operational capacity

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Research staff count Recommended	78	Field-cited	NIHR Sheffield BRC — Collaborating facilities (NIHR Sheffield CRF) https://www.sheffieldbrc.nihr.ac.uk/about-us/collaborating-facilities/nihr-clinical-research-facility Section: Team “Over 78 members of staff work at the Sheffield Clinical Research Facility full-time” Page: https://www.sheffieldbrc.nihr.ac.uk/about-us/collaborating-facilities/nihr-clinical-research-facility	Response for Research staff countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Annual MH trial count Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Sheffield BRC page gives ~150 experimental medicine studies (all specialties), not a mental-health-only annual throughput figure.	Response for Annual MH trial countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active competing studies Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no current competing MH studies count on accessed facility pages.	Response for Active competing studiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Typical monthly recruitment rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no monthly recruitment throughput statistic on accessed facility pages.	Response for Typical monthly recruitment rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
R&D approval timeline (days) Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no Trust R&D turnaround figure on accessed CRF pages.	Response for R&D approval timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Capabilities

Research capabilities available at this site.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Capability: Neuropsychological assessment Recommended	Cognitive Testing · Neuropsychological assessment · Three consultation rooms plus en-suite investigation and treatment rooms supporting structured assessments (including mental health–relevant visits per site copy). · Available	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Facilities list “3 consultation rooms” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities/royal-hallamshire-hospital Linked to neuropsychological / structured assessment capability; dementia-friendly reception context on same page supports MH-relevant visits.	Response for Capability: Neuropsychological assessmentAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Overnight facility Recommended	Specialist Facilities · Overnight facility · Royal Hallamshire CRF includes 2 single bedrooms and a 4-bedded bay with nurses' station for overnight and longer stays. · Available	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Facilities list “2 single bedrooms a fully equipped 4 bedded bay area with nurses' station” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities/royal-hallamshire-hospital	Response for Capability: Overnight facilityAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Biobank (blood/tissue) Recommended	Biobanking · Biobank (blood/tissue) · On-site sample handling laboratory at the Royal Hallamshire Hospital CRF site. · Available	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: Facilities list “an on-site sample handling laboratory” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities/royal-hallamshire-hospital	Response for Capability: Biobank (blood/tissue)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Clinical Research Facility (CRF) Recommended	Specialist Facilities · Clinical Research Facility (CRF) · NIHR Clinical Research Facility across Royal Hallamshire Hospital (O floor) and Northern General Hospital (Centre for Biomedical Research) delivering experimental medicine and clinical trials. · Available	Field-cited	NIHR Sheffield Clinical Research Facility — Official Website https://www.sheffield.crf.nihr.ac.uk/ Section: RHH and NGH “The Royal Hallamshire Hospital (RHH) and Northern General Hospital (NGH) CRFs provide a safe and welcoming environment for delivering clinical research studies.” Page: https://www.sheffield.crf.nihr.ac.uk/about-us/our-facilities	Response for Capability: Clinical Research Facility (CRF)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis experience

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis experience: Schizophrenia Recommended	Schizophrenia · Psychotic Disorders · Some · prev trials: 1	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 export “filter.overallStatus=COMPLETED” Page: https://clinicaltrials.gov/ Query term Sheffield Teaching Hospitals AND (schizophrenia OR psychosis OR psychotic); deduped count 1 total, 0 with completion year >=2016; experience_level=some.	Response for Diagnosis experience: SchizophreniaAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Major depressive disorder Recommended	Major depressive disorder · Mood Disorders · Extensive · prev trials: 32	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 export “filter.overallStatus=COMPLETED” Page: https://clinicaltrials.gov/ Query term Sheffield Teaching Hospitals AND depression; counted completion year >=2016 => 32; extensive (>=5).	Response for Diagnosis experience: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Generalised anxiety disorder Recommended	Generalised anxiety disorder · Anxiety Disorders · Extensive · prev trials: 32	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 export “filter.overallStatus=COMPLETED” Page: https://clinicaltrials.gov/ Query term Sheffield Teaching Hospitals AND anxiety; completion year >=2016 => 32; likely overlap with depression Boolean hits.	Response for Diagnosis experience: Generalised anxiety disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: PTSD Recommended	PTSD · Trauma-Related · Moderate · prev trials: 3	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 export “filter.overallStatus=COMPLETED” Page: https://clinicaltrials.gov/ Query term Sheffield Teaching Hospitals AND PTSD; count 3 => moderate.	Response for Diagnosis experience: PTSDAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Eating disorders (anorexia) Recommended	Eating disorders (anorexia) · Eating Disorders · Extensive · prev trials: 11	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 export “filter.overallStatus=COMPLETED” Page: https://clinicaltrials.gov/ Query term Sheffield Teaching Hospitals AND (eating disorder OR anorexia OR bulimia); completion year >=2016 => 11 => extensive.	Response for Diagnosis experience: Eating disorders (anorexia)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Substance use disorders Recommended	Substance use disorders · Substance Use · Extensive · prev trials: 10	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 export “filter.overallStatus=COMPLETED” Page: https://clinicaltrials.gov/ Query term Sheffield Teaching Hospitals AND (substance OR alcohol OR opioid); completion year >=2016 => 10 => extensive.	Response for Diagnosis experience: Substance use disordersAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Personality disorders (BPD) Recommended	Personality disorders (BPD) · Personality Disorders · Moderate · prev trials: 2	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 export “filter.overallStatus=COMPLETED” Page: https://clinicaltrials.gov/ Query term Sheffield Teaching Hospitals AND (borderline personality OR personality disorder); completion year >=2016 => 2 => moderate.	Response for Diagnosis experience: Personality disorders (BPD)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Dementia / neurodegeneration Recommended	Dementia / neurodegeneration · Neurodegenerative · Moderate · prev trials: 4	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 export “filter.overallStatus=COMPLETED” Page: https://clinicaltrials.gov/ Query term Sheffield Teaching Hospitals AND dementia; completion year >=2016 => 4 => moderate.	Response for Diagnosis experience: Dementia / neurodegenerationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Sleep disorders / insomnia Recommended	Sleep disorders / insomnia · Sleep Disorders · Extensive · prev trials: 19	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Section: API v2 export “filter.overallStatus=COMPLETED” Page: https://clinicaltrials.gov/ Query term Sheffield Teaching Hospitals AND (sleep OR insomnia); completion year >=2016 => 19 => extensive.	Response for Diagnosis experience: Sleep disorders / insomniaAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Linked cohorts

Cohorts hosted at or linked to this site.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked cohorts Optional	No value held	No source yet	No citation linked to this field yet.	Response for Linked cohortsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	ai_inferred	Internal	Internal catalogue field	—	—
Last verified Recommended	16 Apr 2026	Internal	Internal catalogue field	—	—
Data source Recommended	Populated Apr 2026 from NIHR Sheffield CRF pages (home, our facilities, Royal Hallamshire Hospital), Sheffield BRC collaborating facilities page (staff and study counts, PI), OpenStreetMap Nominatim geocode for Royal Hallamshire Hospital (S10 2JF), ClinicalTrials.gov API v2 completed-study Boolean queries for Sheffield Teaching Hospitals, and ISRCTN XML API search smoke-check.	Internal	Internal catalogue field	—	—