Site validation pack

NIHR Sheffield Biomedical Research Centre

Sheffield BRC

Generated 6 Oct 2026, 10:34 · ID 18

AI inferred

Instructions for reviewers

Review each field against your knowledge of this site. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	22 of 40 reviewable fields are cited to a source (55%) · 16 with no source yet · 2 searched — not published · 15 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and organisation

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Site name Required	NIHR Sheffield Biomedical Research Centre	Field-cited	NIHR Sheffield BRC - About https://www.sheffieldbrc.nihr.ac.uk/about-us Section: About “The NIHR Sheffield Biomedical Research Centre (BRC) is part of the NIHR and hosted by Sheffield Teaching Hospitals NHS Foundation Trust in partnership with The University of Sheffield.” Page: https://www.sheffieldbrc.nihr.ac.uk/about-us	Response for Site nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Short name Recommended	Sheffield BRC	Field-cited	NIHR Sheffield BRC - About https://www.sheffieldbrc.nihr.ac.uk/about-us Section: About “The NIHR Sheffield Biomedical Research Centre (BRC) is part of the NIHR...” Page: https://www.sheffieldbrc.nihr.ac.uk/about-us	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Organisation Required	University of Sheffield / Sheffield Teaching Hospitals NHS Foundation Trust	Field-cited	NIHR Sheffield BRC - About https://www.sheffieldbrc.nihr.ac.uk/about-us Section: About “...hosted by Sheffield Teaching Hospitals NHS Foundation Trust in partnership with The University of Sheffield.” Page: https://www.sheffieldbrc.nihr.ac.uk/about-us	Response for OrganisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Site type Recommended	BRC	Field-cited	NIHR Sheffield BRC - Home https://www.sheffieldbrc.nihr.ac.uk/ Section: Homepage “Sheffield has held BRC status since 2016...” Page: https://www.sheffieldbrc.nihr.ac.uk/	Response for Site typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://www.sheffieldbrc.nihr.ac.uk/	Field-cited	NIHR Sheffield BRC - Home https://www.sheffieldbrc.nihr.ac.uk/ Section: Homepage URL “https://www.sheffieldbrc.nihr.ac.uk/” Page: https://www.sheffieldbrc.nihr.ac.uk/	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Description Required	NIHR Sheffield BRC is hosted by Sheffield Teaching Hospitals NHS Foundation Trust in partnership with the University of Sheffield, with research spanning Neuroscience, Cardiovascular Disease, Infection and Immunity, and Imaging and Engineering. The BRC collaborates with SITraN and supports translational neuroscience, including deep-phenotyping, imaging and biomarker-driven research.	Field-cited	NIHR Sheffield BRC - About https://www.sheffieldbrc.nihr.ac.uk/about-us Section: About “Funded by the National Institute for Health and Care Research, we conduct research across four primary themes...” Page: https://www.sheffieldbrc.nihr.ac.uk/about-us	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active site Recommended	Yes	No source yet	No citation linked to this field yet.	Response for Active siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Location and scope

Field	Current value	Evidence	Source evidence	Response	Notes / correction
UK region Recommended	Yorkshire and the Humber	Field-cited	CQC - Sheffield Teaching Hospitals NHS Foundation Trust inspection summary https://www.cqc.org.uk/provider/RHQ/inspection-summary Section: Latest inspection summary “...specialist services for the populations of Yorkshire & Humber, parts of Mid-Yorkshire and North Derbyshire.” Page: https://www.cqc.org.uk/provider/RHQ/inspection-summary	Response for UK regionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Country Recommended	England	Field-cited	CQC - Sheffield Teaching Hospitals NHS Foundation Trust inspection summary https://www.cqc.org.uk/provider/RHQ/inspection-summary Section: Latest inspection summary “...population of 640,000 people in Sheffield and the surrounding areas.” Page: https://www.cqc.org.uk/provider/RHQ/inspection-summary CQC provider profile is an England NHS trust profile.	Response for CountryAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
City Recommended	Sheffield	Field-cited	CQC - Sheffield Teaching Hospitals NHS Foundation Trust inspection summary https://www.cqc.org.uk/provider/RHQ/inspection-summary Section: Latest inspection summary “...population of 640,000 people in Sheffield and the surrounding areas.” Page: https://www.cqc.org.uk/provider/RHQ/inspection-summary	Response for CityAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Latitude Recommended	53.3811000	No source yet	No citation linked to this field yet.	Response for LatitudeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Longitude Recommended	-1.4886000	No source yet	No citation linked to this field yet.	Response for LongitudeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catchment population Recommended	640,000	Field-cited	CQC - Sheffield Teaching Hospitals NHS Foundation Trust inspection summary https://www.cqc.org.uk/provider/RHQ/inspection-summary Section: Latest inspection summary “...population of 640,000 people in Sheffield and the surrounding areas.” Page: https://www.cqc.org.uk/provider/RHQ/inspection-summary	Response for Catchment populationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Contacts and leadership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Contact name Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Principal investigator Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Principal investigatorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
PI email Recommended	No value held	No source yet	No citation linked to this field yet.	Response for PI emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
NHS trust partner Recommended	Sheffield Teaching Hospitals NHS Foundation Trust	Field-cited	NIHR Sheffield BRC - About https://www.sheffieldbrc.nihr.ac.uk/about-us Section: About “...hosted by Sheffield Teaching Hospitals NHS Foundation Trust in partnership with The University of Sheffield.” Page: https://www.sheffieldbrc.nihr.ac.uk/about-us	Response for NHS trust partnerAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Infrastructure

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Pharmacy facilities Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No explicit public statement confirming IMP pharmacy facilities specific to NIHR Sheffield BRC in searched sources (BRC pages, CRF pages, CQC summary, ClinicalTrials.gov query variants, ISRCTN PDF). Set to NULL pending direct confirmation.	Response for Pharmacy facilitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Dedicated research facility Recommended	Yes	Field-cited	NIHR Sheffield Clinical Research Facility - Home https://www.sheffield.crf.nihr.ac.uk/home Section: CRF home “NIHR Clinical Research Facilities (CRFs) are purpose-built facilities in NHS hospitals where researchers can conduct studies.” Page: https://www.sheffield.crf.nihr.ac.uk/home	Response for Dedicated research facilityAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
CRF bed count Recommended	No value held	No source yet	No citation linked to this field yet.	Response for CRF bed countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
EDC experience Recommended	No	No source yet	No citation linked to this field yet.	Response for EDC experienceAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GCP certified Recommended	No	No source yet	No citation linked to this field yet.	Response for GCP certifiedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
NIHR CRN partner Recommended	Yes	Field-cited	NIHR Sheffield Clinical Research Facility - Home https://www.sheffield.crf.nihr.ac.uk/home Section: CRF home “The NIHR Sheffield Clinical Research Facility (CRF) is part of the NIHR...” Page: https://www.sheffield.crf.nihr.ac.uk/home	Response for NIHR CRN partnerAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Operational capacity

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Research staff count Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Research staff countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Annual MH trial count Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Public sources provide trial examples but no authoritative annual mental-health trial count specific to this BRC. Set to NULL rather than retain an unsourced value.	Response for Annual MH trial countAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active competing studies Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Active competing studiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Typical monthly recruitment rate Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Typical monthly recruitment rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
R&D approval timeline (days) Recommended	No value held	No source yet	No citation linked to this field yet.	Response for R&D approval timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Capabilities

Research capabilities available at this site.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Capability: fMRI (3T) Recommended	Imaging · fMRI (3T) · 3T MRI at University of Sheffield imaging centre · Available	Field-cited	University of Sheffield Neuroscience Institute - Facilities https://sheffield.ac.uk/neuroscience-institute/facilities Section: Facilities “The type of experiments that can be performed include structural images, spectroscopy, perfusion, diffusion, and functional MRI.” Page: https://sheffield.ac.uk/neuroscience-institute/facilities	Response for Capability: fMRI (3T)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Structural MRI Recommended	Imaging · Structural MRI · Structural MRI · Available	Field-cited	University of Sheffield Neuroscience Institute - Facilities https://sheffield.ac.uk/neuroscience-institute/facilities Section: Facilities “Our human brain imaging facilities are expanding and currently include:” Page: https://sheffield.ac.uk/neuroscience-institute/facilities	Response for Capability: Structural MRIAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: DTI/Diffusion imaging Recommended	Imaging · DTI/Diffusion imaging · Diffusion imaging · Available	Field-cited	University of Sheffield Neuroscience Institute - Facilities https://sheffield.ac.uk/neuroscience-institute/facilities Section: Facilities “The type of experiments that can be performed include structural images, spectroscopy, perfusion, diffusion, and functional MRI.” Page: https://sheffield.ac.uk/neuroscience-institute/facilities	Response for Capability: DTI/Diffusion imagingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Cognitive testing lab Recommended	Cognitive Testing · Cognitive testing lab · Cognitive testing at SITraN · Available	Field-cited	University of Sheffield Neuroscience Institute - Facilities https://sheffield.ac.uk/neuroscience-institute/facilities Section: Facilities “Cognitive neuroscience and mental health” Page: https://sheffield.ac.uk/neuroscience-institute/facilities	Response for Capability: Cognitive testing labAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Computerised cognitive battery Recommended	Cognitive Testing · Computerised cognitive battery · Computerised cognitive batteries · Available	Field-cited	University of Sheffield Neuroscience Institute - Facilities https://sheffield.ac.uk/neuroscience-institute/facilities Section: Facilities “Cognitive neuroscience and mental health” Page: https://sheffield.ac.uk/neuroscience-institute/facilities	Response for Capability: Computerised cognitive batteryAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Biobank (blood/tissue) Recommended	Biobanking · Biobank (blood/tissue) · SITraN biobank with brain bank material and clinical database of 1,500+ patients · Available	Field-cited	NIHR Sheffield BRC - Neuroscience https://www.sheffieldbrc.nihr.ac.uk/our-research/neuroscience Section: Neuroscience “...clinical database of over 1,500 patients and a vital resource of human brain-bank material.” Page: https://www.sheffieldbrc.nihr.ac.uk/our-research/neuroscience	Response for Capability: Biobank (blood/tissue)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Capability: Clinical Research Facility (CRF) Recommended	Specialist Facilities · Clinical Research Facility (CRF) · NIHR Sheffield CRF · Available	Field-cited	NIHR Sheffield Clinical Research Facility - Home https://www.sheffield.crf.nihr.ac.uk/home Section: CRF home “The NIHR Sheffield Clinical Research Facility (CRF) is part of the NIHR and hosted by Sheffield Teaching Hospitals NHS Foundation Trust in partnership with the University of Sheffield.” Page: https://www.sheffield.crf.nihr.ac.uk/home	Response for Capability: Clinical Research Facility (CRF)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis experience

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis experience: Major depressive disorder Recommended	Major depressive disorder · Mood Disorders · Some · prev trials: 1	Field-cited	ISRCTN68347173 - Sheffield City Region Health-led Trial https://doi.org/10.1186/ISRCTN68347173 Section: Plain English summary “...mild to moderate mental health and/or physical health conditions...” Page: https://www.isrctn.com/pdf/ISRCTN68347173 At least one completed Sheffield-including trial with depression/anxiety outcomes supports SOME experience for mood disorders. ISRCTN68347173 - Sheffield City Region Health-led Trial https://doi.org/10.1186/ISRCTN68347173 Section: Locations “Sheffield Teaching Hospitals NHS Foundation Trust ... Study participating centre” Page: https://www.isrctn.com/pdf/ISRCTN68347173 Set previous_trial_count=1 for diagnosis_area_id=5 based on direct registry evidence.	Response for Diagnosis experience: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis experience: Dementia / neurodegeneration Recommended	Dementia / neurodegeneration · Neurodegenerative · Extensive · prev trials: 6	Field-cited	ClinicalTrials.gov query - Royal Hallamshire Hospital and mental health https://clinicaltrials.gov/api/v2/studies?query.term=%22Royal%20Hallamshire%20Hospital%22%20AND%20mental%20health&pageSize=100 Section: ClinicalTrials API output “totalReturned=31 for query 'Royal Hallamshire Hospital' AND mental health” Page: https://clinicaltrials.gov/api/v2/studies?query.term=%22Royal%20Hallamshire%20Hospital%22%20AND%20mental%20health&pageSize=100 Registry output includes multiple Alzheimer's/dementia studies associated with Sheffield; >=5 supports EXTENSIVE experience. ClinicalTrials.gov query - Royal Hallamshire Hospital and mental health https://clinicaltrials.gov/api/v2/studies?query.term=%22Royal%20Hallamshire%20Hospital%22%20AND%20mental%20health&pageSize=100 Section: ClinicalTrials API output “NCT05399888 ... Alzheimer's Disease Dementia” Page: https://clinicaltrials.gov/api/v2/studies?query.term=%22Royal%20Hallamshire%20Hospital%22%20AND%20mental%20health&pageSize=100 Conservative count set to 6 based on dementia/Alzheimer's-related entries in registry results.	Response for Diagnosis experience: Dementia / neurodegenerationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Linked cohorts

Cohorts hosted at or linked to this site.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked cohorts Optional	No value held	No source yet	No citation linked to this field yet.	Response for Linked cohortsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	ai_inferred	Internal	Internal catalogue field	—	—
Last verified Recommended	No value held	Internal	Internal catalogue field	—	—
Data source Recommended	No value held	Internal	Internal catalogue field	—	—