Cohort validation pack

IMAGEN

IMAGEN Study

Generated 6 Oct 2026, 10:36 · ID 87

AI inferred

Last verified: 09/08/2026

Instructions for reviewers

Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Summary of how well fields in this pack are linked to evidence.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	13 of 70 reviewable fields are cited to a source (19%) · 52 with no source yet · 5 searched — not published · 28 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and ownership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Short name Required	IMAGEN	Field-cited	Catalogue of Mental Health Measures — study index entry: IMAGEN https://www.cataloguementalhealth.ac.uk/search Section: Study index “IMAGEN” Page: https://www.cataloguementalhealth.ac.uk/search	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Full name Required	IMAGEN Study	No source yet	No citation linked to this field yet.	Response for Full nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Managing organisation Recommended	IMAGEN Consortium (UK arm: King's College London, IoPPN)	Field-cited	Schumann et al. — The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology, Molecular Psychiatry 2010 https://doi.org/10.1038/mp.2010.4 Section: Author affiliations Page: https://doi.org/10.1038/mp.2010.4 Multi-country IMAGEN consortium coordinated from the Institute of Psychiatry (now IoPPN), King's College London; DIGIT row anchors the UK arm at the IoPPN.	Response for Managing organisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Primary site Recommended	Institute of Psychiatry, Psychology & Neuroscience (site #13)	Field-cited	Schumann et al. — The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology, Molecular Psychiatry 2010 https://doi.org/10.1038/mp.2010.4 Section: Author affiliations Page: https://doi.org/10.1038/mp.2010.4 London recruitment and coordination run from the IoPPN (site id 13).	Response for Primary siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://imagen-europe.com/	Field-cited	IMAGEN Consortium — Official Website https://imagen-europe.com/ Page: https://imagen-europe.com/ Consortium website; page content not machine-readable at population time (access blocked), URL recorded from public listings.	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catalogue of Mental Health Measures URL Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Catalogue of Mental Health Measures URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact name Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Summary and status

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Description Required	European longitudinal imaging-genetics cohort following around 2,000 young people and their parents from age 14, combining structural and functional neuroimaging, genome-wide genotyping, cognitive and behavioural assessment, and mental health measures across repeated follow-up waves into adulthood. London is one of the founding recruitment sites alongside Nottingham and centres in Ireland, France, and Germany.	Field-cited	Catalogue of Mental Health Measures — study index entry: IMAGEN https://www.cataloguementalhealth.ac.uk/search Section: Study index “The IMAGEN Study is a large-scale longitudinal study that has been following 2,000 young people and their parents from the age of 14. The study combines brain imaging, genetics and psychiatry to look at adolescent brain development and behaviour.” Page: https://www.cataloguementalhealth.ac.uk/search	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N Required	2,000	Field-cited	Catalogue of Mental Health Measures — study index entry: IMAGEN https://www.cataloguementalhealth.ac.uk/search Section: Study index “Sample size at recruitment: 2,000” Page: https://www.cataloguementalhealth.ac.uk/search	Response for Total NAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N qualifier Recommended	approximate	No source yet	No citation linked to this field yet.	Response for Total N qualifierAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Year established Recommended	2007	Field-cited	Catalogue of Mental Health Measures — study index entry: IMAGEN https://www.cataloguementalhealth.ac.uk/search Section: Study index “Start year: 2007” Page: https://www.cataloguementalhealth.ac.uk/search	Response for Year establishedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active cohort Recommended	Yes	No source yet	No citation linked to this field yet.	Response for Active cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ongoing recruitment Recommended	No	No source yet	No citation linked to this field yet.	Response for Ongoing recruitmentAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Refreshed cohort Recommended	Yes	No source yet	No citation linked to this field yet.	Response for Refreshed cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recontact success rate Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Recontact success rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Retention rate Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Retention rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Published references Recommended	10.1038/mp.2010.4	No source yet	No citation linked to this field yet.	Response for Published referencesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Notes Recommended	Multi-country consortium cohort; the DIGIT row reflects the UK arm anchored at the IoPPN. Repeated waves (ages 14, 16, 19, 22+) justify is_refreshed. Widely used for biomarker and target-validation research including industry collaborations via the consortium.	No source yet	No citation linked to this field yet.	Response for NotesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

3D cohort mapping

Consent, characterisation, and data availability axes used on the cohort map.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent level (axis) Required	3 — Broad consent (recontactable for future studies)	Not published	Schumann et al. — The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology, Molecular Psychiatry 2010 https://doi.org/10.1038/mp.2010.4 Score 3: actively consented research participants followed across waves with recontact for follow-up assessments (broad research consent, recontactable).	Response for Consent level (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Characterisation depth (axis) Required	3 — Multi-domain MH characterisation	Not published	Schumann et al. — The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology, Molecular Psychiatry 2010 https://doi.org/10.1038/mp.2010.4 Score 3: multi-domain research characterisation (DAWBA-based psychiatric assessment, cognition, behaviour) beyond standardised instruments alone; not scored 4 because refresh cycles are wave-based rather than continuous deep phenotyping.	Response for Characterisation depth (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data availability (axis) Required	4 — Multi-modal	Not published	Schumann et al. — The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology, Molecular Psychiatry 2010 https://doi.org/10.1038/mp.2010.4 Score 4: multi-modal — questionnaires, cognition, DNA/genotyping, and structural/functional MRI; auto-derived from the data type flags (imaging + genomic + biosamples).	Response for Data availability (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cohort map group (derived) Recommended	Group 1	Internal	Internal catalogue field	—	—
Population type Recommended	General population	Not published	Catalogue of Mental Health Measures — study index entry: IMAGEN https://www.cataloguementalhealth.ac.uk/search general_population: recruited from schools/community at age 14 without health-based entry criteria; deep phenotype does not change the sampling frame.	Response for Population typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Industry engagement status Recommended	Unknown	Not published	Searched — not published UNSOURCEABLE: consortium collaborations with industry exist in the literature but no public statement of an access process for commercial studies; default unknown pending an owner conversation.	Response for Industry engagement statusAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Parent cohort / programme Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Parent cohort / programmeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TWiCs eligible Recommended	No	No source yet	No citation linked to this field yet.	Response for TWiCs eligibleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data modalities

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Questionnaire / interview Recommended	Yes	No source yet	No citation linked to this field yet.	Response for Questionnaire / interviewAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cognitive testing Recommended	Yes	No source yet	No citation linked to this field yet.	Response for Cognitive testingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Physical measures Recommended	No	No source yet	No citation linked to this field yet.	Response for Physical measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosamples Recommended	Yes	No source yet	No citation linked to this field yet.	Response for BiosamplesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genomic data Recommended	Yes	No source yet	No citation linked to this field yet.	Response for Genomic dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Omics Recommended	No	No source yet	No citation linked to this field yet.	Response for OmicsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging Recommended	Yes	No source yet	No citation linked to this field yet.	Response for ImagingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Wearable / sensor Recommended	No	No source yet	No citation linked to this field yet.	Response for Wearable / sensorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Digital phenotyping Recommended	No	No source yet	No citation linked to this field yet.	Response for Digital phenotypingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked health records Recommended	No	No source yet	No citation linked to this field yet.	Response for Linked health recordsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosample types Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Biosample typesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genotyping platform Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Genotyping platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging modalities Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Imaging modalitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Mental health measures Recommended	Development and Well-Being Assessment (DAWBA), Strengths and Difficulties Questionnaire (SDQ)	Field-cited	Schumann et al. — The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology, Molecular Psychiatry 2010 https://doi.org/10.1038/mp.2010.4 Section: Methods Page: https://doi.org/10.1038/mp.2010.4 DAWBA and SDQ are core instruments in the IMAGEN assessment battery.	Response for Mental health measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data subcategories

Structured modality and subcategory rows used alongside the high-level data-type flags.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Data subcategories Recommended List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.	No value held	No source yet	No citation linked to this field yet.	Response for Data subcategoriesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Data subcategories

Recommended

List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Consent and use permissions

Specific use permissions separate from the 3D consent-level axis.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent and use permissions Recommended Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.	No value held	No source yet	No citation linked to this field yet.	Response for Consent and use permissionsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Consent and use permissions

Recommended

Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Access pathways

One or more routes by which researchers can request or analyse data.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Access pathways Recommended Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.	No value held	No source yet	No citation linked to this field yet.	Response for Access pathwaysAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Access pathways

Recommended

Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Within-cohort coverage

Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Within-cohort coverage metrics Recommended Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.	No value held	No source yet	No citation linked to this field yet.	Response for Within-cohort coverage metricsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Within-cohort coverage metrics

Recommended

Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Linkage and access

Field	Current value	Evidence	Source evidence	Response	Notes / correction
NHS linkage Recommended	No	No source yet	No citation linked to this field yet.	Response for NHS linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GP linkage Recommended	No	No source yet	No citation linked to this field yet.	Response for GP linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Death registry linkage Recommended	No	No source yet	No citation linked to this field yet.	Response for Death registry linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Education linkage Recommended	No	No source yet	No citation linked to this field yet.	Response for Education linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access mechanism Recommended	collaboration	Field-cited	Catalogue of Mental Health Measures — study index entry: IMAGEN https://www.cataloguementalhealth.ac.uk/search Section: Study index “Data access: Contact study team” Page: https://www.cataloguementalhealth.ac.uk/search Mapped to collaboration: access via consortium application and collaboration.	Response for Data access mechanismAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TRE platform Recommended	No value held	No source yet	No citation linked to this field yet.	Response for TRE platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data dictionary URL Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Data dictionary URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access timeline (days) Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Data access timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access cost Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Data access costAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Participant profile and dates

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Age distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Age distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Sex distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Sex distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ethnicity distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Ethnicity distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Smoking status distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Smoking status distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Median age Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Median ageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent female Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Percent femaleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent non-white Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Percent non-whiteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	multi_site	No source yet	No citation linked to this field yet.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Follow-up duration Recommended	Age 14 baseline (2007-2010) with follow-up waves at ages 16, 19, and 22+	No source yet	No citation linked to this field yet.	Response for Follow-up durationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Last data collection date Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Last data collection dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment start date Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Recruitment start dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment end date Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Recruitment end dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis areas

Mental health diagnosis areas represented in this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis area: Major depressive disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Major depressive disorder · Mood Disorders	Field-cited	Schumann et al. — The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology, Molecular Psychiatry 2010 https://doi.org/10.1038/mp.2010.4 Page: https://doi.org/10.1038/mp.2010.4 Depression among core longitudinal mental health outcomes; area-level N not published.	Response for Diagnosis area: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Generalised anxiety disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Generalised anxiety disorder · Anxiety Disorders	Field-cited	Schumann et al. — The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology, Molecular Psychiatry 2010 https://doi.org/10.1038/mp.2010.4 Page: https://doi.org/10.1038/mp.2010.4 Anxiety phenotypes assessed via DAWBA-based measures; area-level N not published.	Response for Diagnosis area: Generalised anxiety disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: ADHD Recommended Confirm this diagnosis area applies and estimated N if shown.	ADHD · Neurodevelopmental	Field-cited	Schumann et al. — The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology, Molecular Psychiatry 2010 https://doi.org/10.1038/mp.2010.4 Page: https://doi.org/10.1038/mp.2010.4 ADHD symptom phenotypes assessed in the behavioural battery; area-level N not published.	Response for Diagnosis area: ADHDAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Substance use disorders Recommended Confirm this diagnosis area applies and estimated N if shown.	Substance use disorders · Substance Use	Field-cited	Schumann et al. — The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology, Molecular Psychiatry 2010 https://doi.org/10.1038/mp.2010.4 Page: https://doi.org/10.1038/mp.2010.4 Substance use / reinforcement-related behaviour is a central study theme; area-level N not published.	Response for Diagnosis area: Substance use disordersAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Linked sites

Sites contributing participants or data to this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked sites Optional	No value held	No source yet	No citation linked to this field yet.	Response for Linked sitesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	ai_inferred	Internal	Internal catalogue field	—	—
Last verified Recommended	9 Aug 2026	Internal	Internal catalogue field	—	—
Data source Recommended	Populated Aug 2026 from Schumann et al. 2010 Molecular Psychiatry (design, measures, sites), the IMAGEN consortium website, and the Catalogue of Mental Health Measures study index entry (N, start year, coverage, access route). Pending verification with the KCL IMAGEN team.	Internal	Internal catalogue field	—	—