Cohort validation pack

SEP-MD

Social and Economic Predictors of the Severe Mental Disorders

Generated 6 Oct 2026, 10:35 · ID 85

AI inferred

Last verified: 09/08/2026

Instructions for reviewers

Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Summary of how well fields in this pack are linked to evidence.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	10 of 69 reviewable fields are cited to a source (14%) · 53 with no source yet · 6 searched — not published · 32 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and ownership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Short name Required	SEP-MD	Field-cited	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Section: Study index “Social and Economic Predictors of the Severe Mental Disorders (SEP-MD) Study” Page: https://www.cataloguementalhealth.ac.uk/search	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Full name Required	Social and Economic Predictors of the Severe Mental Disorders	Field-cited	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Section: Study index “Social and Economic Predictors of the Severe Mental Disorders (SEP-MD) Study” Page: https://www.cataloguementalhealth.ac.uk/search	Response for Full nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Managing organisation Recommended	King's College London / South London and Maudsley NHS Foundation Trust	Field-cited	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Section: Study index “South London and Maudsley Trust patients” Page: https://www.cataloguementalhealth.ac.uk/search SLaM-record-based study run with King's College London researchers; recorded jointly pending confirmation of the lead institution.	Response for Managing organisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Primary site Recommended	NIHR Maudsley Biomedical Research Centre (site #1)	No source yet	No citation linked to this field yet.	Response for Primary siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no dedicated public study website identified at population time; CMHM index is the discovery source.	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catalogue of Mental Health Measures URL Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Catalogue of Mental Health Measures URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact name Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Summary and status

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Description Required	Linked cohort connecting 2011 Census records with de-identified electronic health records for around 20,000 South London and Maudsley patients who are experiencing or have experienced a severe mental health condition. Built to study how neighbourhood and individual social and economic factors influence mortality, in-patient admissions, and long-term worklessness in severe mental illness.	Field-cited	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Section: Study index “SEP-MD links census data with electronic health records for 20,000 South London and Maudsley Trust patients who are experiencing or have experienced a severe mental health condition.” Page: https://www.cataloguementalhealth.ac.uk/search	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N Required	19,808	Field-cited	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Section: Study index “Sample size at recruitment: 19,808” Page: https://www.cataloguementalhealth.ac.uk/search	Response for Total NAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N qualifier Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Total N qualifierAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Year established Recommended	2018	Field-cited	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Section: Study index “Start year: 2018” Page: https://www.cataloguementalhealth.ac.uk/search	Response for Year establishedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active cohort Recommended	Yes	No source yet	No citation linked to this field yet.	Response for Active cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ongoing recruitment Recommended	No	No source yet	No citation linked to this field yet.	Response for Ongoing recruitmentAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Refreshed cohort Recommended	No	No source yet	No citation linked to this field yet.	Response for Refreshed cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recontact success rate Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Recontact success rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Retention rate Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Retention rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Published references Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Published referencesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Notes Recommended	Records-based data resource, not a recontactable participant cohort: analyses run on de-identified census-linked EHR data under research governance. Feasibility value for severe-mental-illness study planning (social determinants, service-use outcomes) rather than patient supply.	No source yet	No citation linked to this field yet.	Response for NotesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

3D cohort mapping

Consent, characterisation, and data availability axes used on the cohort map.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent level (axis) Required	2 — Section 251 / CAG (pseudonymised, no individual consent)	Not published	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Score 2: de-identified census-EHR linkage under research governance without individual research consent, matching the CRIS SLaM precedent (cohort 22) in the consent decision tree (records-based, no consent to contact).	Response for Consent level (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Characterisation depth (axis) Required	1 — Routine EHR	Not published	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Score 1: characterisation comes from routine clinical records and census sociodemographics, not standardised research instruments.	Response for Characterisation depth (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data availability (axis) Required	2 — Records + research data	Not published	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Score 1: clinical/administrative records only; auto-derived from has_linked_health_records with no research, biological, or multi-modal layers.	Response for Data availability (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cohort map group (derived) Recommended	Group 4	Internal	Internal catalogue field	—	—
Population type Recommended	Data resource	Not published	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search data_resource: clinical (SMI) population held as a de-identified linked records asset, not a recontactable recruited cohort.	Response for Population typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Industry engagement status Recommended	Unknown	Not published	Searched — not published UNSOURCEABLE: engagement status is an organisational property of the custodian, not publicly documented; default unknown pending an owner conversation.	Response for Industry engagement statusAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Parent cohort / programme Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Parent cohort / programmeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TWiCs eligible Recommended	No	No source yet	No citation linked to this field yet.	Response for TWiCs eligibleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data modalities

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Questionnaire / interview Recommended	No	No source yet	No citation linked to this field yet.	Response for Questionnaire / interviewAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cognitive testing Recommended	No	No source yet	No citation linked to this field yet.	Response for Cognitive testingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Physical measures Recommended	No	No source yet	No citation linked to this field yet.	Response for Physical measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosamples Recommended	No	No source yet	No citation linked to this field yet.	Response for BiosamplesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genomic data Recommended	No	No source yet	No citation linked to this field yet.	Response for Genomic dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Omics Recommended	No	No source yet	No citation linked to this field yet.	Response for OmicsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging Recommended	No	No source yet	No citation linked to this field yet.	Response for ImagingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Wearable / sensor Recommended	No	No source yet	No citation linked to this field yet.	Response for Wearable / sensorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Digital phenotyping Recommended	No	No source yet	No citation linked to this field yet.	Response for Digital phenotypingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked health records Recommended	Yes	No source yet	No citation linked to this field yet.	Response for Linked health recordsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosample types Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Biosample typesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genotyping platform Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Genotyping platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging modalities Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Imaging modalitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Mental health measures Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Mental health measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data subcategories

Structured modality and subcategory rows used alongside the high-level data-type flags.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Data subcategories Recommended List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.	No value held	No source yet	No citation linked to this field yet.	Response for Data subcategoriesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Data subcategories

Recommended

List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Consent and use permissions

Specific use permissions separate from the 3D consent-level axis.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent and use permissions Recommended Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.	No value held	No source yet	No citation linked to this field yet.	Response for Consent and use permissionsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Consent and use permissions

Recommended

Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Access pathways

One or more routes by which researchers can request or analyse data.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Access pathways Recommended Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.	No value held	No source yet	No citation linked to this field yet.	Response for Access pathwaysAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Access pathways

Recommended

Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Within-cohort coverage

Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Within-cohort coverage metrics Recommended Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.	No value held	No source yet	No citation linked to this field yet.	Response for Within-cohort coverage metricsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Within-cohort coverage metrics

Recommended

Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Linkage and access

Field	Current value	Evidence	Source evidence	Response	Notes / correction
NHS linkage Recommended	Yes	No source yet	No citation linked to this field yet.	Response for NHS linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GP linkage Recommended	No	No source yet	No citation linked to this field yet.	Response for GP linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Death registry linkage Recommended	Yes	No source yet	No citation linked to this field yet.	Response for Death registry linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Education linkage Recommended	No	No source yet	No citation linked to this field yet.	Response for Education linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access mechanism Recommended	collaboration	Field-cited	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Section: Study index “Data access: Contact study team” Page: https://www.cataloguementalhealth.ac.uk/search Mapped to collaboration: access requires working with the study team under SLaM/CRIS research governance.	Response for Data access mechanismAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TRE platform Recommended	No value held	No source yet	No citation linked to this field yet.	Response for TRE platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data dictionary URL Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Data dictionary URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access timeline (days) Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Data access timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access cost Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Data access costAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Participant profile and dates

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Age distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Age distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Sex distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Sex distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ethnicity distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Ethnicity distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Smoking status distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Smoking status distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Median age Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Median ageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent female Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Percent femaleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent non-white Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Percent non-whiteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	regional	No source yet	No citation linked to this field yet.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Follow-up duration Recommended	Census 2011 baseline with ongoing EHR follow-up	No source yet	No citation linked to this field yet.	Response for Follow-up durationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Last data collection date Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Last data collection dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment start date Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Recruitment start dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment end date Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Recruitment end dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis areas

Mental health diagnosis areas represented in this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis area: Schizophrenia Recommended Confirm this diagnosis area applies and estimated N if shown.	Schizophrenia · Psychotic Disorders	Field-cited	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Section: Study index “patients who are experiencing or have experienced a severe mental health condition” Page: https://www.cataloguementalhealth.ac.uk/search Schizophrenia is a core severe mental disorder in the cohort definition; diagnosis-specific N not published.	Response for Diagnosis area: SchizophreniaAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Bipolar disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Bipolar disorder · Mood Disorders	Field-cited	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Section: Study index “severe mental health condition” Page: https://www.cataloguementalhealth.ac.uk/search Bipolar disorder within the severe mental disorders definition; diagnosis-specific N not published.	Response for Diagnosis area: Bipolar disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Major depressive disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Major depressive disorder · Mood Disorders	Field-cited	Catalogue of Mental Health Measures — study index entry: SEP-MD https://www.cataloguementalhealth.ac.uk/search Section: Study index “severe mental health condition” Page: https://www.cataloguementalhealth.ac.uk/search Severe depression within the SMI definition; diagnosis-specific N not published.	Response for Diagnosis area: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Diagnosis area: Schizophrenia

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Schizophrenia · Psychotic Disorders

Field-cited

Catalogue of Mental Health Measures — study index entry: SEP-MD
https://www.cataloguementalhealth.ac.uk/search
Section: Study index
“patients who are experiencing or have experienced a severe mental health condition”
Page: https://www.cataloguementalhealth.ac.uk/search
Schizophrenia is a core severe mental disorder in the cohort definition; diagnosis-specific N not published.

AccurateNeeds correctionNot sureDoes not apply

Diagnosis area: Bipolar disorder

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Bipolar disorder · Mood Disorders

Field-cited

Catalogue of Mental Health Measures — study index entry: SEP-MD
https://www.cataloguementalhealth.ac.uk/search
Section: Study index
“severe mental health condition”
Page: https://www.cataloguementalhealth.ac.uk/search
Bipolar disorder within the severe mental disorders definition; diagnosis-specific N not published.

AccurateNeeds correctionNot sureDoes not apply

Diagnosis area: Major depressive disorder

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Major depressive disorder · Mood Disorders

Field-cited

Catalogue of Mental Health Measures — study index entry: SEP-MD
https://www.cataloguementalhealth.ac.uk/search
Section: Study index
“severe mental health condition”
Page: https://www.cataloguementalhealth.ac.uk/search
Severe depression within the SMI definition; diagnosis-specific N not published.

AccurateNeeds correctionNot sureDoes not apply

Linked sites

Sites contributing participants or data to this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked sites Optional	No value held	No source yet	No citation linked to this field yet.	Response for Linked sitesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	ai_inferred	Internal	Internal catalogue field	—	—
Last verified Recommended	9 Aug 2026	Internal	Internal catalogue field	—	—
Data source Recommended	Populated Aug 2026 from the Catalogue of Mental Health Measures study index entry for SEP-MD (design, N, coverage, access route) and docs/data-dictionary.md scoring rules. Pending verification against a published cohort profile and the study team.	Internal	Internal catalogue field	—	—