Seed data — not verified. Approximate data from public sources, not yet confirmed by cohort leads or site reps.

Why?
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Cohort validation pack

NSHD

MRC National Survey of Health and Development

Generated 6 Oct 2026, 10:36 · ID 75

AI inferred

Last verified: 16/04/2026

Instructions for reviewers

  • Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
  • Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
  • Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

74

Total fields

40

Field-cited

0

Whole-record source only

7

AI-inferred, no source yet

22

Searched — not published

18

No value held

29

Needs review

Source coverage

Summary of how well fields in this pack are linked to evidence.

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction
Field-level source coverage

Optional

40 of 69 reviewable fields are cited to a source (58%) · 7 with no source yet · 22 searched — not published · 18 with no value heldComputed

No citation linked to this field yet.

Response for Field-level source coverage

Identity and ownership

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction
Short name

Required

NSHDField-cited
Response for Short name
Full name

Required

MRC National Survey of Health and DevelopmentField-cited
Response for Full name
Managing organisation

Recommended

MRC Unit for Lifelong Health and Ageing, University College LondonField-cited
Response for Managing organisation
Primary site

Recommended

No value heldNot published
  • Searched — not published

    UNSOURCEABLE as sites.id: NSHD is led by the MRC Unit for Lifelong Health and Ageing at UCL but there is no matching dedicated site row in db/seed/sites/ for that unit; cohort is national rather than a single trial site.

Response for Primary site
Website URL

Recommended

https://nshd.mrc.ac.uk/Field-cited
  • NSHD — public website (MRC/UCL)

    https://nshd.mrc.ac.uk/

    Section: Additional information / Website

    “nshd.mrc.ac.uk”
Response for Website URL
Catalogue of Mental Health Measures URL

Recommended

https://www.cataloguementalhealth.ac.uk/NSHDField-cited
  • Catalogue of Mental Health Measures

    https://www.cataloguementalhealth.ac.uk

    Section: Official sitemap study URL

    “https://www.cataloguementalhealth.ac.uk/NSHD”

    Page: https://www.cataloguementalhealth.ac.uk/NSHD

Response for Catalogue of Mental Health Measures URL
Contact name

Recommended

No value heldNot published
  • Searched — not published

    UNSOURCEABLE: footer lists email/phone but not a named contact person in the downloaded homepage HTML.

Response for Contact name
Contact email

Recommended

mrclha.enquiries@ucl.ac.ukField-cited
Response for Contact email

Summary and status

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction
Description

Required

Ongoing national birth cohort of 5,362 singleton births sampled from all births in England, Scotland and Wales in one week of March 1946, with repeated postal and face-to-face data collections across the life course covering physical, cognitive and mental health. The study maintains a large variable archive (Skylark/Condor documentation) and hosts neuroscience imaging work including the Insight 46 sub-study described on the public website.Field-cited
  • Skylark — NSHD Data Sharing wiki (UCL)

    https://skylark.ucl.ac.uk/NSHD/
    “The Medical Research Council (MRC) National Survey of Health of Development (NSHD) is an ongoing cohort study involving 5,362 men and women born in England, Scotland and Wales, who have been followed up since their birth in March 1946. Over the 70+ year follow-up, study participants have provided information about their health and life circumstances, and taken part in a wide range of tests of their physical, cognitive and mental health”
Response for Description
Total N

Required

5,362Field-cited
Response for Total N
Total N qualifier

Recommended

at_birthField-cited
Response for Total N qualifier
Year established

Recommended

1946Field-cited
Response for Year established
Active cohort

Recommended

YesField-cited
Response for Active cohort
Ongoing recruitment

Recommended

NoField-cited
Response for Ongoing recruitment
Refreshed cohort

Recommended

YesField-cited
  • Kuh et al. — The MRC National Survey of Health and Development reaches age 70 (Eur J Epidemiol 2016)

    https://doi.org/10.1007/s10654-016-0217-8
    “a third (32%) had participated in all 23 previous data collections”
Response for Refreshed cohort

Recontact success rate

Recommended

No value heldNot published
  • Searched — not published

    UNSOURCEABLE: sources report wave participation rates but not a cohort-level recontact success rate field as defined in the data dictionary.

Response for Recontact success rate

Retention rate

Recommended

49.38Field-cited
Response for Retention rate

Published references

Recommended

doi:10.1007/s10654-016-0217-8Field-cited
Response for Published references
Notes

Recommended

Also known as the 1946 Birth Cohort (per Catalogue of Mental Health Measures). Sample is not augmented; representativeness is limited to single, native-born individuals born to married mothers still resident in England, Wales or Scotland per catalogue sample description.Field-cited
Response for Notes

3D cohort mapping

Consent, characterisation, and data availability axes used on the cohort map.

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction
Consent level (axis)

Required

3 — Broad consent (recontactable for future studies)Field-cited
  • Skylark — NSHD Data Sharing wiki (UCL)

    https://skylark.ucl.ac.uk/NSHD/
    “The study members right to privacy, and the ethical conduct of all researchers accessing the data, must be guaranteed.”
Response for Consent level (axis)
Characterisation depth (axis)

Required

3 — Multi-domain MH characterisationField-cited
  • Catalogue of Mental Health Measures — NSHD study profile

    https://www.cataloguementalhealth.ac.uk/?content=study&studyid=NSHD
    “During their childhood, the main aim of the NSHD was to investigate how the environment at home and at school affected physical and mental development and educational attainment. During adulthood, the main aim was to investigate how childhood health and development and lifetime social circumstances affected their adult health and function and how these change with age.”
Response for Characterisation depth (axis)
Data availability (axis)

Required

4 — Multi-modalField-cited
  • Skylark — NSHD Data Sharing wiki (UCL)

    https://skylark.ucl.ac.uk/NSHD/
    “Insight 46 neuroscience sub-study”
Response for Data availability (axis)
Cohort map group (derived)

Recommended

Group 1Internal

Internal catalogue field

——
Population type

Recommended

General populationNot published
  • DIGIT Cohort Portfolio Review — population type and engagement classification (Aug 2026)

Response for Population type
Industry engagement status

Recommended

UnknownNot published
  • Searched — not published

    UNSOURCEABLE: industry engagement status is an organisational property of the custodian and is not publicly documented; default 'unknown' pending a cohort-owner meeting.

Response for Industry engagement status
Parent cohort / programme

Recommended

No value heldNo source yet

No citation linked to this field yet.

Response for Parent cohort / programme
TWiCs eligible

Recommended

NoNot published
Response for TWiCs eligible

Data modalities

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction
Questionnaire / interview

Recommended

YesField-cited
  • Kuh et al. — The MRC National Survey of Health and Development reaches age 70 (Eur J Epidemiol 2016)

    https://doi.org/10.1007/s10654-016-0217-8

    Section: Abstract

    “We report the participation patterns for a postal questionnaire and home visit at 68–69 years of study members in the MRC National Survey of Health and Development”
Response for Questionnaire / interview
Cognitive testing

Recommended

YesField-cited
Response for Cognitive testing
Physical measures

Recommended

YesField-cited
  • Kuh et al. — The MRC National Survey of Health and Development reaches age 70 (Eur J Epidemiol 2016)

    https://doi.org/10.1007/s10654-016-0217-8
    “bone density imaging”
Response for Physical measures
Biosamples

Recommended

YesField-cited
Response for Biosamples
Genomic data

Recommended

YesField-cited
Response for Genomic data
Omics

Recommended

NoNot published
  • Searched — not published

    UNSOURCEABLE TRUE/FALSE: sources confirm genetics and blood biochemistry but do not explicitly document separate proteomics/metabolomics/transcriptomics/epigenomics archives accessible to external researchers; set FALSE conservatively.

Response for Omics
Imaging

Recommended

YesField-cited
Response for Imaging
Wearable / sensor

Recommended

NoNot published
  • Searched — not published

    UNSOURCEABLE TRUE: no wearable/accelerometry modality described in the downloaded HTML/XML sources used.

Response for Wearable / sensor
Digital phenotyping

Recommended

NoNot published
  • Searched — not published

    UNSOURCEABLE TRUE: Related themes mention Digital technology and social media but the downloaded catalogue text does not confirm passive digital phenotyping datasets; set FALSE per conservative rule.

Response for Digital phenotyping
Linked health records

Recommended

YesField-cited
Response for Linked health records
Biosample types

Recommended

blood, DNAField-cited
Response for Biosample types
Genotyping platform

Recommended

No value heldNot published
  • Searched — not published

    UNSOURCEABLE: catalogue confirms genetic data collected but does not name array/chip or sequencing platform in the downloaded HTML.

Response for Genotyping platform
Imaging modalities

Recommended

structural_mriField-cited
  • NSHD — public website (MRC/UCL)

    https://nshd.mrc.ac.uk/
    “brain scan”
Response for Imaging modalities
Mental health measures

Recommended

Pittsburgh Fatigability ScaleField-cited
  • Kuh et al. — The MRC National Survey of Health and Development reaches age 70 (Eur J Epidemiol 2016)

    https://doi.org/10.1007/s10654-016-0217-8

    Section: Acknowledgements

    “We also thank Dr Nancy W Glynn and Dr Adam Santanasto of the University of Pittsburgh for their advice in using the Pittsburgh Fatigability Scale.”
Response for Mental health measures

Data subcategories

Structured modality and subcategory rows used alongside the high-level data-type flags.

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction

Data subcategories

Recommended

List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.

No value heldNo source yet

No citation linked to this field yet.

Response for Data subcategories

Consent and use permissions

Specific use permissions separate from the 3D consent-level axis.

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction

Consent and use permissions

Recommended

Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.

No value heldNo source yet

No citation linked to this field yet.

Response for Consent and use permissions

Access pathways

One or more routes by which researchers can request or analyse data.

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction

Access pathways

Recommended

Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.

No value heldNo source yet

No citation linked to this field yet.

Response for Access pathways

Within-cohort coverage

Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction

Within-cohort coverage metrics

Recommended

Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.

No value heldNo source yet

No citation linked to this field yet.

Response for Within-cohort coverage metrics

Linkage and access

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction
NHS linkage

Recommended

NoNot published
  • Searched — not published

    UNSOURCEABLE TRUE: catalogue confirms administrative health linkage but the checkbox text does not explicitly name NHS hospital (HES) records; left FALSE.

Response for NHS linkage
GP linkage

Recommended

NoNot published
  • Searched — not published

    UNSOURCEABLE TRUE: no GP-record linkage called out in the downloaded sources used.

Response for GP linkage
Death registry linkage

Recommended

NoNot published
  • Searched — not published

    UNSOURCEABLE TRUE: death registry linkage not described in the downloaded sources used.

Response for Death registry linkage
Education linkage

Recommended

NoNot published
  • Searched — not published

    UNSOURCEABLE TRUE: education administrative linkage not described in the downloaded sources used (education appears as a research theme, not linkage).

Response for Education linkage
Data access mechanism

Recommended

direct_applicationField-cited
  • Skylark — NSHD Data Sharing wiki (UCL)

    https://skylark.ucl.ac.uk/NSHD/
    “If you wish to apply for NSHD data, please complete the data sharing form”
Response for Data access mechanism
TRE platform

Recommended

No value heldNot published
  • Searched — not published

    UNSOURCEABLE: NSHD uses Condor/Showcase/Skylark infrastructure per Skylark page, which is not one of the exemplar TRE/SDE labels in the data dictionary examples.

Response for TRE platform
Data dictionary URL

Recommended

https://skylark.ucl.ac.uk/NSHD/Field-cited
  • Skylark — NSHD Data Sharing wiki (UCL)

    https://skylark.ucl.ac.uk/NSHD/
    “Skylark contains data access information”
Response for Data dictionary URL
Data access timeline (days)

Recommended

No value heldNot published
  • Searched — not published

    UNSOURCEABLE: no typical turnaround days stated in downloaded pages.

Response for Data access timeline (days)
Data access cost

Recommended

No value heldNot published
  • Searched — not published

    UNSOURCEABLE: no fee schedule captured in downloaded pages.

Response for Data access cost

Participant profile and dates

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction
Age distribution

Recommended

birth_cohort_1946: 1Not published
Response for Age distribution
Sex distribution

Recommended

No value heldNot published
  • Searched — not published

    UNSOURCEABLE JSON: catalogue lists Sex as All without male/female percentages in the downloaded study profile HTML.

Response for Sex distribution
Ethnicity distribution

Recommended

No value heldNot published
  • Searched — not published

    UNSOURCEABLE JSON: no ethnicity percentage table in the downloaded pages; catalogue notes representativeness limits for immigrants rather than reporting ethnicity splits.

Response for Ethnicity distribution
Smoking status distribution

Recommended

No value heldNo source yet

No citation linked to this field yet.

Response for Smoking status distribution
Median age

Recommended

80.0Field-cited
  • NSHD — public website (MRC/UCL)

    https://nshd.mrc.ac.uk/
    “Happy 80th Birthday”
Response for Median age
Percent female

Recommended

No value heldNot published
  • Searched — not published

    UNSOURCEABLE: catalogue sample card lists Sex as All without a female percentage in the downloaded HTML.

Response for Percent female
Percent non-white

Recommended

No value heldNot published
  • Searched — not published

    UNSOURCEABLE: no non-white percentage in downloaded sources.

Response for Percent non-white
Geographic coverage

Recommended

nationalField-cited
Response for Geographic coverage
Follow-up duration

Recommended

70+ years (1946–present)Field-cited
Response for Follow-up duration
Last data collection date

Recommended

31 Dec 2016Field-cited
Response for Last data collection date
Recruitment start date

Recommended

1 Mar 1946Field-cited
Response for Recruitment start date
Recruitment end date

Recommended

8 Mar 1946Field-cited
Response for Recruitment end date

Diagnosis areas

Mental health diagnosis areas represented in this cohort.

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction
Diagnosis area: Major depressive disorder

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Major depressive disorder · Mood DisordersField-cited
  • Catalogue of Mental Health Measures — NSHD study profile

    https://www.cataloguementalhealth.ac.uk/?content=study&studyid=NSHD
    “During adulthood, the main aim was to investigate how childhood health and development and lifetime social circumstances affected their adult health and function”
Response for Diagnosis area: Major depressive disorder
Diagnosis area: Generalised anxiety disorder

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Generalised anxiety disorder · Anxiety DisordersField-cited
  • Catalogue of Mental Health Measures — NSHD study profile

    https://www.cataloguementalhealth.ac.uk/?content=study&studyid=NSHD
    “During adulthood, the main aim was to investigate how childhood health and development and lifetime social circumstances affected their adult health and function”
Response for Diagnosis area: Generalised anxiety disorder
Diagnosis area: Dementia / neurodegeneration

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Dementia / neurodegeneration · NeurodegenerativeField-cited
  • NSHD — public website (MRC/UCL)

    https://nshd.mrc.ac.uk/

    Section: Neuroimaging clinical study

    “detecting brain changes that might help predict who is at greater risk of developing dementia and Alzheimer's disease”
Response for Diagnosis area: Dementia / neurodegeneration

Linked sites

Sites contributing participants or data to this cohort.

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction
Linked sites

Optional

No value heldNo source yet

No citation linked to this field yet.

Response for Linked sites

Verification metadata

Internal catalogue status — for reference only.

FieldCurrent valueEvidenceSource evidenceResponseNotes / correction
Verification status

Recommended

ai_inferredInternal

Internal catalogue field

——
Last verified

Recommended

16 Apr 2026Internal

Internal catalogue field

——
Data source

Recommended

Populated Apr 2026 from Skylark NSHD wiki (https://skylark.ucl.ac.uk/NSHD/), NSHD public website (https://nshd.mrc.ac.uk/), Catalogue of Mental Health Measures NSHD study page, and Kuh et al. 2016 Eur J Epidemiol open-access full text (PMC5206260 XML via Europe PMC).Internal

Internal catalogue field

——