Cohort validation pack

LBC1936

Lothian Birth Cohort 1936

Generated 6 Oct 2026, 10:36 · ID 74

AI inferred

Last verified: 16/04/2026

Instructions for reviewers

Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Summary of how well fields in this pack are linked to evidence.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	41 of 69 reviewable fields are cited to a source (59%) · 6 with no source yet · 22 searched — not published · 21 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and ownership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Short name Required	LBC1936	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “LBC1936; N = 1091” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml DIGIT short label LBC1936 matches the abbreviated cohort name used in the cohort profile abstract alongside LBC1921.	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Full name Required	Lothian Birth Cohort 1936	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “1936 (LBC1936; N = 1091)” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml DIGIT full_name is the public expansion Lothian Birth Cohort 1936, consistent with the LBC1936 label in the indexed abstract text (the journal title also references the 1921 and 1936 cohorts together).	Response for Full nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Managing organisation Recommended	University of Edinburgh (Centre for Clinical Brain Sciences / CCBS)	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “University of Edinburgh-based Lothian Birth Cohorts” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml CCBS / ageing-centre stewardship is implied by Edinburgh-based cohort description; DIGIT row names CCBS as the contemporary research home for LBC1936.	Response for Managing organisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Primary site Recommended	University of Edinburgh (site #12)	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Author metadata (PMC HTML) “Department of Psychology, University of Edinburgh” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/ primary_site_id=12 maps to the University of Edinburgh DIGIT site row as the lead institution hosting the LBC1936 programme.	Response for Primary siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://doi.org/10.1093/ije/dyr197	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: PubMed XML ArticleId “10.1093/ije/dyr197” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Cohort website_url set to https://doi.org/10.1093/ije/dyr197 (canonical cohort profile); DOI string copied from the PubMed XML ELocationId element; dedicated .ed.ac.uk cohort homepage was not reliably retrievable in this population environment.	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catalogue of Mental Health Measures URL Recommended	https://www.cataloguementalhealth.ac.uk/LBC1936	Field-cited	Catalogue of Mental Health Measures https://www.cataloguementalhealth.ac.uk Section: Official sitemap study URL “https://www.cataloguementalhealth.ac.uk/LBC1936” Page: https://www.cataloguementalhealth.ac.uk/LBC1936	Response for Catalogue of Mental Health Measures URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact name Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no single named cohort operations contact is asserted in the reviewed PubMed abstract or BMC protocol sections.	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no public mailbox for data access is quoted in the reviewed sources.	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Summary and status

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Description Required	Regional ageing cohort of 1091 community-dwelling survivors of the June 1947 Scottish Mental Survey living in the Lothian (chiefly Edinburgh) area, recruited from 2004 with repeated waves into older age. Childhood Moray House Test scores at age ~11 are linked to late-life cognitive, medical, personality (including IPIP), and psycho-social assessments; blood DNA and biomarkers; and (in later programme phases) detailed structural brain MRI, with cohort profile papers describing ongoing follow-up and broad phenotype coverage.	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: PubMed XML abstract “As they have childhood intelligence test scores, the cohorts' data have been used to search for determinants of lifetime cognitive changes, and also cognitive change within old age.” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml DIGIT description paraphrases the PubMed abstract and BMC design paper; verbatim childhood-IQ linkage quote is taken from the PubMed XML abstract.	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N Required	1,091	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Recruitment results “In total, 1091 individuals became participants in the Lothian Birth Cohort 1936 study and completed the tests and questionnaires” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/ Corroborates the recruited analytic sample size used in the later cohort profile. NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “LBC1936; N = 1091” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml	Response for Total NAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N qualifier Recommended	No value held	Not published	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 NULL: 1091 is an enumerated completed-participant total in primary sources, not an approximate/target figure requiring a data-dictionary qualifier.	Response for Total N qualifierAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Year established Recommended	2004	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Recruitment timing “Between June 2004 and November 2006, 3686 invitations were sent out” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/ year_established=2004 aligns with the first invitation wave start month in the design paper.	Response for Year establishedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active cohort Recommended	Yes	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “are being seen at 76 years” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Ongoing follow-up waves described in cohort profile update → is_active=TRUE.	Response for Active cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ongoing recruitment Recommended	No	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “are being seen at 76 years” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml ongoing_recruitment=FALSE: later waves are follow-up of an enumerated recruited cohort rather than open population recruitment.	Response for Ongoing recruitmentAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Refreshed cohort Recommended	Yes	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “examined at mean ages of 70 and 73 years, and are being seen at 76 years” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml	Response for Refreshed cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recontact success rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: headline recontact response percentage not extracted from reviewed sources in this pass.	Response for Recontact success rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Retention rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: single retention percentage not quoted in the PubMed abstract or BMC recruitment paragraphs used here.	Response for Retention rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Published references Recommended	doi:10.1093/ije/dyr197, doi:10.1186/1471-2318-7-28	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: BMC HTML citation “doi:10.1186/1471-2318-7-28” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/ Secondary published_references provenance row for the open-access design and methods paper DOI. Europe PMC API — IJE dyr197 metadata https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI:10.1093/ije/dyr197&format=json Section: Europe PMC lite JSON “"doi":"10.1093/ije/dyr197"” Page: https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=DOI:10.1093/ije/dyr197&format=json Array includes cohort profile DOI plus BMC design paper DOI as secondary canonical protocol reference.	Response for Published referencesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Notes Recommended	Baseline design and examination battery (including HADS and DNA sampling) are described in the 2007 BMC Geriatrics open-access protocol paper; cohort profile update with MRI and genotyping context is in the 2012 International Journal of Epidemiology cohort profile.	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Recruitment + measurements “1091 individuals became participants ... completed the tests and questionnaires” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/	Response for NotesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

3D cohort mapping

Consent, characterisation, and data availability axes used on the cohort map.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent level (axis) Required	3 — Broad consent (recontactable for future studies)	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Introduction to the LBC1936 study and consent “Ethics permission for the study protocol was granted by the Multi-Centre Research Ethics Committee for Scotland.” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/ Participants are identifiable community volunteers completing repeated research visits and linked records (see IJE note on routine data sources). No study-wide interventional randomisation-ready consent described → consent_level=3 per data-dictionary.md.	Response for Consent level (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Characterisation depth (axis) Required	4 — Deep phenotyping, refreshed	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “Both cohorts have a wide range of variables: genome-wide genotyping, demographics, psycho-social and lifestyle factors, cognitive functions, medical history and examination, and biomarkers (from blood and urine). The LBC1936 participants also have a detailed structural magnetic resonance imaging (MRI) brain scan.” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Multi-domain phenotyping with research-grade imaging and bioscience plus repeated waves supports characterisation_depth=4 (deep phenotyping with refresh) per data-dictionary.md.	Response for Characterisation depth (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data availability (axis) Required	4 — Multi-modal	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “Both cohorts have a wide range of variables: genome-wide genotyping, demographics, psycho-social and lifestyle factors, cognitive functions, medical history and examination, and biomarkers (from blood and urine). The LBC1936 participants also have a detailed structural magnetic resonance imaging (MRI) brain scan.” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml DERIVED per data-dictionary.md: hasResearch=TRUE (questionnaires/cognitive/medical history); hasBiological=TRUE (blood/urine biomarkers + genotyping); hasAdvanced=TRUE (structural MRI) → data_availability=4 without requiring administrative record linkage flags.	Response for Data availability (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cohort map group (derived) Recommended	Group 1	Internal	Internal catalogue field	—	—
Population type Recommended	General population	Not published	DIGIT Cohort Portfolio Review — population type and engagement classification (Aug 2026) Classified general_population in the DIGIT cohort portfolio review (Aug 2026). Community-dwelling survivors of the 1947 Scottish Mental Survey; population sample.	Response for Population typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Industry engagement status Recommended	Unknown	Not published	Searched — not published UNSOURCEABLE: industry engagement status is an organisational property of the custodian and is not publicly documented; default 'unknown' pending a cohort-owner meeting.	Response for Industry engagement statusAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Parent cohort / programme Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Parent cohort / programmeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TWiCs eligible Recommended	No	Not published	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml FALSE: consent_level=3 and no study-wide interventional randomisation-ready consent described in reviewed text.	Response for TWiCs eligibleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data modalities

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Questionnaire / interview Recommended	Yes	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: LBC1936 Study Questionnaire sections “LBC1936 Study Questionnaire Section 1” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/	Response for Questionnaire / interviewAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cognitive testing Recommended	Yes	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Cognitive tests “Cognitive tests” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/ Includes repeated Moray House ability testing and extensive neuropsychological battery described around this heading.	Response for Cognitive testingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Physical measures Recommended	Yes	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Physical examination and interview “height; weight; corrected and uncorrected visual acuity” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/	Response for Physical measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosamples Recommended	Yes	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Blood samples “They provided blood samples for DNA extraction and testing and other biomarker analyses.” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/	Response for BiosamplesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genomic data Recommended	Yes	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “genome-wide genotyping” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml	Response for Genomic dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Omics Recommended	No	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “biomarkers (from blood and urine)” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml FALSE per DIGIT boundary used elsewhere: biochemistry and targeted blood assays are captured under biosamples/genomics; named multi-omics platforms (transcriptomics/proteomics) are not asserted in the abstract text.	Response for OmicsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging Recommended	Yes	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “detailed structural magnetic resonance imaging (MRI) brain scan” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml	Response for ImagingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Wearable / sensor Recommended	No	Not published	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml FALSE: reviewed IJE abstract and BMC design headings do not describe continuous wearable device phenotyping for LBC1936.	Response for Wearable / sensorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Digital phenotyping Recommended	No	Not published	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml FALSE: no app- or device-stream digital phenotyping module is described in the reviewed PubMed abstract or BMC design sections.	Response for Digital phenotypingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked health records Recommended	No	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: PubMed XML abstract “medical history and examination, and biomarkers (from blood and urine). The LBC1936 participants also have a detailed structural magnetic resonance imaging (MRI) brain scan.” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml FALSE conservative: PubMed-indexed abstract text used here does not explicitly assert administrative NHS record linkage as a packaged resource (Table footnotes in the full PDF may add detail; not cited in this pass).	Response for Linked health recordsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosample types Recommended	blood, urine	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “biomarkers (from blood and urine)” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml	Response for Biosample typesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genotyping platform Recommended	No value held	Not published	Searched — not published UNSOURCEABLE in this pass: IJE text asserts genome-wide genotyping but does not name a specific array vendor/chip in the Europe PMC lite JSON payload reviewed.	Response for Genotyping platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging modalities Recommended	structural_mri	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “detailed structural magnetic resonance imaging (MRI) brain scan” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml ARRAY stores structural_mri as the modality explicitly named for LBC1936.	Response for Imaging modalitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Mental health measures Recommended	Hospital Anxiety and Depression Scale (HADS), International Personality Item Pool (IPIP)	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: BMC section heading “Hospital Anxiety Depression Scale” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/ HADS supports depression and anxiety diagnosis-area mapping; IPIP is evidenced by questionnaire section headings in the same protocol paper HTML.	Response for Mental health measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data subcategories

Structured modality and subcategory rows used alongside the high-level data-type flags.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Data subcategories Recommended List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.	No value held	No source yet	No citation linked to this field yet.	Response for Data subcategoriesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Data subcategories

Recommended

List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Consent and use permissions

Specific use permissions separate from the 3D consent-level axis.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent and use permissions Recommended Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.	No value held	No source yet	No citation linked to this field yet.	Response for Consent and use permissionsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Consent and use permissions

Recommended

Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Access pathways

One or more routes by which researchers can request or analyse data.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Access pathways Recommended Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.	No value held	No source yet	No citation linked to this field yet.	Response for Access pathwaysAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Access pathways

Recommended

Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Within-cohort coverage

Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Within-cohort coverage metrics Recommended Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.	No value held	No source yet	No citation linked to this field yet.	Response for Within-cohort coverage metricsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Within-cohort coverage metrics

Recommended

Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Linkage and access

Field	Current value	Evidence	Source evidence	Response	Notes / correction
NHS linkage Recommended	No	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: PubMed XML abstract “medical history and examination” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml FALSE: abstract medical history wording is not explicit SMR/NHS administrative linkage for research extracts.	Response for NHS linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GP linkage Recommended	No	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: PubMed XML abstract “medical history and examination” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml FALSE: GP record linkage not named in the PubMed-indexed abstract text reviewed.	Response for GP linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Death registry linkage Recommended	No	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: PubMed XML abstract “follow-up of the University of Edinburgh-based Lothian Birth Cohorts” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml FALSE conservative: civil registration / mortality linkage not explicitly asserted in the PubMed abstract XML reviewed here.	Response for Death registry linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Education linkage Recommended	No	Not published	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml FALSE: education administrative linkage is not asserted in the reviewed IJE abstract note or BMC recruitment sections.	Response for Education linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access mechanism Recommended	collaboration	Not published	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml collaboration: mature Edinburgh-led programme datasets typically require academic collaboration / governed access; no open bulk download asserted in reviewed sources.	Response for Data access mechanismAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TRE platform Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: safe haven / TRE product name for curated LBC1936 analysis datasets is not named in the reviewed PubMed abstract or BMC design paper HTML.	Response for TRE platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data dictionary URL Recommended	https://doi.org/10.1093/ije/dyr197	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: DOI “10.1093/ije/dyr197” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Uses cohort profile DOI as the canonical published variable overview entry point.	Response for Data dictionary URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access timeline (days) Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: turnaround not stated in reviewed sources.	Response for Data access timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access cost Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: costs not stated in reviewed sources.	Response for Data access costAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Participant profile and dates

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Age distribution Recommended	older_adults_wave1_mean_age_70: 1	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “recruited for these cohorts at mean ages of 79 (LBC1921) and 70 (LBC1936)” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml JSON placeholder encodes dominant late-life baseline band for DIGIT filters; not a full histogram.	Response for Age distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Sex distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE in reviewed open snapshots: Table 1 sex counts for LBC1936 wave 1 are not extracted into the Europe PMC lite JSON or the BMC HTML excerpts used for this pass.	Response for Sex distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ethnicity distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: cohort profile abstract and BMC design sections reviewed do not provide a publishable ethnicity JSON breakdown for DIGIT.	Response for Ethnicity distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Smoking status distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Smoking status distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Median age Recommended	70.0	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “mean ages of 79 (LBC1921) and 70 (LBC1936)” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml median_age=70.0 aligns to the wave-1 mean age wording for LBC1936 in the cohort profile abstract.	Response for Median ageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent female Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: sex percentages not present in the Europe PMC lite JSON payload; full IJE Table 1 not machine-extracted here.	Response for Percent femaleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent non-white Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: ethnicity percentages not present in reviewed sources for this pass.	Response for Percent non-whiteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	regional	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “University of Edinburgh-based Lothian Birth Cohorts” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml geographic_coverage=regional: Edinburgh/Lothian recruitment frame (not UK-wide).	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Follow-up duration Recommended	20+ years (2004–present; waves at mean ages ~70, 73 and later follow-up per cohort profile)	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: Abstract “examined at mean ages of 70 and 73 years, and are being seen at 76 years” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml	Response for Follow-up durationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Last data collection date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE as a single DATE: multiple waves through late life; cohort profile lists several mean-age waves rather than one closure date.	Response for Last data collection dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment start date Recommended	1 Jun 2004	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Recruitment timing “Between June 2004 and November 2006” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/ recruitment_start_date anchored to first invitation wave month.	Response for Recruitment start dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment end date Recommended	No value held	Not published	NULL: programme continued enrichment and later waves beyond the initial 2004–2006 mailing window described for first-pass invitations.	Response for Recruitment end dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis areas

Mental health diagnosis areas represented in this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis area: Major depressive disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Major depressive disorder · Mood Disorders · est. n=1,091	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Hospital Anxiety Depression Scale “Hospital Anxiety Depression Scale” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/ HADS includes depression items supporting mapping to Major depressive disorder (diagnosis_area_id=5). NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: PubMed XML abstract “1936 (LBC1936; N = 1091)” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml estimated_n uses recruited cohort size as upper-bound exposure for mood phenotyping in the full sample.	Response for Diagnosis area: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Generalised anxiety disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Generalised anxiety disorder · Anxiety Disorders · est. n=1,091	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Hospital Anxiety Depression Scale “Hospital Anxiety Depression Scale” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/ HADS includes anxiety items supporting mapping to Generalised anxiety disorder (diagnosis_area_id=8). NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: PubMed XML abstract “1936 (LBC1936; N = 1091)” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml estimated_n uses recruited cohort size as upper-bound exposure for anxiety phenotyping in the full sample.	Response for Diagnosis area: Generalised anxiety disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Dementia / neurodegeneration Recommended Confirm this diagnosis area applies and estimated N if shown.	Dementia / neurodegeneration · Neurodegenerative · est. n=1,091	Field-cited	NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: PubMed XML abstract “1936 (LBC1936; N = 1091)” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml estimated_n uses recruited cohort size as the analysed ageing/MRI sample frame. NCBI E-utilities — PubMed XML (PMID 22253310) https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Section: PubMed XML abstract “Both samples have an emphasis on the ageing of cognitive functions as outcomes.” Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml Structural MRI sentence in the same abstract supports neuroimaging-led cognitive ageing / neurodegeneration research uses (diagnosis_area_id=20).	Response for Diagnosis area: Dementia / neurodegenerationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Diagnosis area: Major depressive disorder

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Major depressive disorder · Mood Disorders · est. n=1,091

Field-cited

Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics)
https://doi.org/10.1186/1471-2318-7-28
Section: Hospital Anxiety Depression Scale
“Hospital Anxiety Depression Scale”
Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/
HADS includes depression items supporting mapping to Major depressive disorder (diagnosis_area_id=5).
NCBI E-utilities — PubMed XML (PMID 22253310)
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml
Section: PubMed XML abstract
“1936 (LBC1936; N = 1091)”
Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml
estimated_n uses recruited cohort size as upper-bound exposure for mood phenotyping in the full sample.

AccurateNeeds correctionNot sureDoes not apply

Diagnosis area: Generalised anxiety disorder

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Generalised anxiety disorder · Anxiety Disorders · est. n=1,091

Field-cited

Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics)
https://doi.org/10.1186/1471-2318-7-28
Section: Hospital Anxiety Depression Scale
“Hospital Anxiety Depression Scale”
Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/
HADS includes anxiety items supporting mapping to Generalised anxiety disorder (diagnosis_area_id=8).
NCBI E-utilities — PubMed XML (PMID 22253310)
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml
Section: PubMed XML abstract
“1936 (LBC1936; N = 1091)”
Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml
estimated_n uses recruited cohort size as upper-bound exposure for anxiety phenotyping in the full sample.

AccurateNeeds correctionNot sureDoes not apply

Diagnosis area: Dementia / neurodegeneration

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Dementia / neurodegeneration · Neurodegenerative · est. n=1,091

Field-cited

NCBI E-utilities — PubMed XML (PMID 22253310)
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml
Section: PubMed XML abstract
“1936 (LBC1936; N = 1091)”
Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml
estimated_n uses recruited cohort size as the analysed ageing/MRI sample frame.
NCBI E-utilities — PubMed XML (PMID 22253310)
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml
Section: PubMed XML abstract
“Both samples have an emphasis on the ageing of cognitive functions as outcomes.”
Page: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=22253310&retmode=xml
Structural MRI sentence in the same abstract supports neuroimaging-led cognitive ageing / neurodegeneration research uses (diagnosis_area_id=20).

AccurateNeeds correctionNot sureDoes not apply

Linked sites

Sites contributing participants or data to this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked site: University of Edinburgh Recommended	University of Edinburgh · Scotland	Field-cited	Deary et al. 2007 — The Lothian Birth Cohort 1936: design and recruitment (BMC Geriatrics) https://doi.org/10.1186/1471-2318-7-28 Section: Author metadata “Department of Psychology, University of Edinburgh” Page: https://pmc.ncbi.nlm.nih.gov/articles/PMC2222601/ cohort_sites row (74,12) links LBC1936 to the University of Edinburgh site record. NULL: local_n not used; national/regional denominator is total_n on cohort row.	Response for Linked site: University of EdinburghAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	ai_inferred	Internal	Internal catalogue field	—	—
Last verified Recommended	16 Apr 2026	Internal	Internal catalogue field	—	—
Data source Recommended	Populated Apr 2026 from Deary et al. (Int J Epidemiol 2012, DOI 10.1093/ije/dyr197; Europe PMC metadata JSON), Deary et al. (BMC Geriatrics 2007, DOI 10.1186/1471-2318-7-28; PMC2222601 HTML snapshot), and docs/data-dictionary.md scoring ladders.	Internal	Internal catalogue field	—	—