Cohort validation pack

UK-REACH

United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers

Generated 6 Oct 2026, 10:36 · ID 68

AI inferred

Last verified: 16/04/2026

Instructions for reviewers

Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Summary of how well fields in this pack are linked to evidence.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	48 of 73 reviewable fields are cited to a source (66%) · 7 with no source yet · 18 searched — not published · 16 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and ownership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Short name Required	UK-REACH	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Title “Cohort Profile: The United Kingdom Research study into Ethnicity and COVID-19 outcomes in Healthcare workers (UK-REACH)”	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Full name Required	United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Title “The United Kingdom Research study into Ethnicity and COVID-19 outcomes in Healthcare workers (UK-REACH)”	Response for Full nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Managing organisation Recommended	University of Leicester / UK-REACH Study Collaborative	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: UK-REACH Collaborative group “Manish Pareek (Chief investigator), Laura Gray (University of Leicester), Laura Nellums (University of Nottingham), Anna L Guyatt (University of Leicester), Catherine John (University of Leicester), I Chris McManus (University College London), Katherine Woolf (University College London), Ibrahim Akubakar (University College London), Amit Gupta (Oxford University Hospitals), Keith R Abrams (University of York), Martin D Tobin (University of Leicester), Louise Wain (University of Leicester), Sue Carr (University Hospital Leicester), Edward Dove (University of Edinburgh), Kamlesh Khunti (University of Leicester), David Ford (University of Swansea), Robert Free (University of Leicester).” managing_organisation summarises coordinating university plus collaborative branding as published.	Response for Managing organisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Primary site Recommended	NIHR Leicester Biomedical Research Centre (site #64)	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Corresponding author + affiliations “Corresponding author. Department of Infection and HIV Medicine, Leicester Royal Infirmary, Leicester, LE1 5WW, UK. E-mail: manish.pareek@leicester.ac.uk” primary_site_id=64 maps to NIHR Leicester Biomedical Research Centre in this database (University Hospitals of Leicester / University of Leicester partnership), aligning with Leicester lead centre and NIHR BRC support cited in funding.	Response for Primary siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://www.uk-reach.org/	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Who is in the cohort? “Interested participants were directed to the cohort website (https://www.uk-reach.org)”	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catalogue of Mental Health Measures URL Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Catalogue of Mental Health Measures URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact name Recommended	Professor Manish Pareek (Chief Investigator)	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Can I get hold of the data? “Interested researchers are encouraged to contact the study management team and principal investigator Professor Manish Pareek via uk-reach@leicester.ac.uk.”	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	uk-reach@leicester.ac.uk	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Can I get hold of the data? “uk-reach@leicester.ac.uk”	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Summary and status

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Description Required	UK-wide prospective occupational cohort of healthcare and ancillary workers (baseline recruitment December 2020–February 2021) examining ethnicity-related differences in SARS-CoV-2/COVID-19 outcomes, workplace exposures, wellbeing and long-term sequelae. Data collection combines remote online questionnaires (baseline and follow-up waves), optional saliva collection for DNA, qualitative work packages and longitudinal linkage to electronic healthcare records (up to 25 years from consent).	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Why was the cohort set up? + Key Features “UK-REACH is a UK-wide prospective cohort established in November 2020 in response to the COVID-19 pandemic.” Description synthesises Key Features (qualitative and quantitative data; recruitment via regulators/trusts) and aims paragraph on clinical outcomes, roles, wellbeing, and EHR linkage duration.	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N Required	17,891	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Who is in the cohort? “In total, 17 891 HCWs from across the UK have been recruited into the study.”	Response for Total NAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N qualifier Recommended	No value held	Field-cited	DIGIT — data-dictionary.md excerpt (Cohort Groups table) Section: Total N Qualifiers “\| `approximate` \| Approximate \| The figure is an estimate, not an exact count. \| Use when the source gives a round number or uses "approximately", "around", "~". \|” Page: https://github.com/DIGIT-MHG/digit-capabilities-db/blob/main/docs/data-dictionary.md UNSOURCEABLE: cohort profile gives an enumerated recruited total (17 891) without DIGIT qualifier keywords; no `exact` enum exists in the Total N Qualifiers table on file → total_n_qualifier NULL.	Response for Total N qualifierAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Year established Recommended	2020	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Why was the cohort set up? “UK-REACH is a UK-wide prospective cohort established in November 2020 in response to the COVID-19 pandemic.” year_established=2020 from establishment month.	Response for Year establishedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active cohort Recommended	Yes	Field-cited	UK-REACH study website (homepage) https://www.uk-reach.org/ Section: OpenGraph meta “The United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers” Live public website title/description (2026-04-16 snapshot) indicates maintained programme presence → is_active=TRUE.	Response for Active cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ongoing recruitment Recommended	No	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Who is in the cohort? “continued until 28 February 2021.” Primary baseline recruitment window closed Feb 2021 → ongoing_recruitment=FALSE (follow-ups continue but new baseline intake closed).	Response for Ongoing recruitmentAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Refreshed cohort Recommended	Yes	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: How often have they been followed up? “Additional follow-up surveys have been planned for every 6 months until 2025, with questions based upon similar topics to those already used and additional questions to provide insight into novel research questions.” Periodic questionnaire waves to maintain currency → is_refreshed=TRUE per data-dictionary refreshed cohort definition.	Response for Refreshed cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recontact success rate Recommended	No value held	Not published	UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: no single recontact success metric published in sources on file; NULL.	Response for Recontact success rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Retention rate Recommended	No value held	Not published	UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: follow-up questionnaire response rates reported but not equivalent to a single cohort retention_rate field without harmonisation guidance; NULL.	Response for Retention rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Published references Recommended	10.1093/ije/dyac171, 10.1136/bmjopen-2021-050647	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Header + References “doi: 10.1093/ije/dyac171” Array includes cohort profile DOI; second DOI 10.1136/bmjopen-2021-050647 sourced separately (protocol HTML snapshot). UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 Section: HTML head metadata “<meta name="citation_doi" content="10.1136/bmjopen-2021-050647">” Second published_references element is the BMJ Open protocol DOI; verbatim meta tag substring from downloaded PMC HTML snapshot.	Response for Published referencesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Notes Recommended	Trial registration ISRCTN11811602 (reported in cohort profile). Chief investigator and coordinating centre: University of Leicester / Leicester Royal Infirmary (correspondence address in publication).	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Ethics approval “Trial ID: ISRCTN11811602.” Notes combine ISRCTN line with chief investigator attribution from Collaborative group block in same source file. Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 “anxiety, depression and post-traumatic stress.” Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 “post-traumatic stress disorder checklist—civilian version (PCL-C)” Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 “\| Long COVID \|” Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 “\| Physical and mental health, wellbeing \|”	Response for NotesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

3D cohort mapping

Consent, characterisation, and data availability axes used on the cohort map.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent level (axis) Required	3 — Broad consent (recontactable for future studies)	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Who is in the cohort? “Interested participants were directed to the cohort website (https://www.uk-reach.org) where they were able to provide contact details along with informed electronic consent, including permission to link to electronic healthcare records (EHRs) and to share pseudonymized research data with external researchers and to consent to participation in prize draws.” Step1 identifiable participants (account + consent) = YES. Step2 S251-only access without consent = NO. Step3 recontact/further data collection via questionnaires and optional DNA kit invites = YES broad future research participation. Step4 specific interventional randomisation consent (TWiCs-level) not described as primary design → Level 3 broad/recontactable observational cohort.	Response for Consent level (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Characterisation depth (axis) Required	3 — Multi-domain MH characterisation	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: What has been measured? “In brief, questions included information about physical and mental wellbeing based upon the General Practice physical activity questionnaire (GPPAQ), EQ-5D and the post-traumatic stress disorder checklist—civilian version (PCL-C).” Validated MH instruments (PCL-C, EQ-5D) plus additional domains (physical activity GPPAQ; trait/state psychological measures per same section) → characterisation_depth=3 multi-domain without research-grade diagnostic interview schedule (SCID/MINI) as primary phenotype.	Response for Characterisation depth (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data availability (axis) Required	3 — Adds biological specimens/molecular data	Not published	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 DERIVED per data-dictionary.md: hasResearch = questionnaire OR cognitive OR physical_measures OR linked_health_records → TRUE (questionnaire + physical + linked). hasBiological = biosamples OR genomic OR omics → TRUE (saliva DNA consent). hasAdvanced = imaging OR wearable OR digital phenotyping → FALSE. Therefore data_availability=3.	Response for Data availability (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cohort map group (derived) Recommended	Group 2	Internal	Internal catalogue field	—	—
Population type Recommended	Occupational	Not published	DIGIT Cohort Portfolio Review — population type and engagement classification (Aug 2026) Classified occupational in the DIGIT cohort portfolio review (Aug 2026). Occupational cohort of healthcare and ancillary workers recruited during COVID-19.	Response for Population typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Industry engagement status Recommended	Unknown	Not published	Searched — not published UNSOURCEABLE: industry engagement status is an organisational property of the custodian and is not publicly documented; default 'unknown' pending a cohort-owner meeting.	Response for Industry engagement statusAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Parent cohort / programme Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Parent cohort / programmeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TWiCs eligible Recommended	No	Not published	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 FALSE: consent_level=3 observational cohort without documented within-cohort randomisation platform for TWiCs.	Response for TWiCs eligibleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data modalities

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Questionnaire / interview Recommended	Yes	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Key Features “Online questionnaires include information on demographics, COVID-19 exposures at work and home, redeployment in the workforce due to COVID-19, mental health measures, workforce attrition and opinions on COVID-19 vaccines, with baseline (n = 15 119), 6 (n = 5632) and 12-month follow-up (n = 6535) data captured.”	Response for Questionnaire / interviewAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cognitive testing Recommended	No	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: What has been measured? “Trait and psychological measures were measured using questions from the Understanding Society cohort questionnaires, a brief version of Levenson's Locus of Control Scale and fatalism questions from Shen et al.” No named neuropsychological cognitive test battery (e.g. CANTAB) is listed; trait/psychological self-report scales are not scored as has_cognitive_data=TRUE under conservative DIGIT flag use → FALSE.	Response for Cognitive testingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Physical measures Recommended	Yes	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: What has been measured? “questions included information about physical and mental wellbeing based upon the General Practice physical activity questionnaire (GPPAQ), EQ-5D and the post-traumatic stress disorder checklist—civilian version (PCL-C).” GPPAQ and EQ-5D capture physical activity / health-related quality of life domains → has_physical_measures=TRUE.	Response for Physical measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosamples Recommended	Yes	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: How often have they been followed up? “Between 18 October and 26 November 2021, participants were invited to provide consent to be sent a saliva sample kit to collect DNA data (n = 3976, response rate = 22.2% of consented participants). The samples were stored at the UK Biocentre (Milton Keynes, UK) after initial processing.”	Response for BiosamplesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genomic data Recommended	Yes	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Key Features “consent to obtain genomic sequencing data collected via saliva”	Response for Genomic dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Omics Recommended	No	Not published	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 FALSE: cohort profile describes DNA via saliva; no metabolomics/proteomics/transcriptomics platform asserted in cited sections → conservative FALSE.	Response for OmicsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging Recommended	No	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: How often have they been followed up? “As UK-REACH is a UK-wide cohort study, no physical examinations of participants take place, with all interactions with participants conducted remotely via e-mail.” Remote-only design without imaging modules described → has_imaging_data=FALSE.	Response for ImagingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Wearable / sensor Recommended	No	Not published	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 FALSE: no wearable device data stream described in Key Features / methods excerpts reviewed.	Response for Wearable / sensorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Digital phenotyping Recommended	No	Not published	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 FALSE: passive digital phenotyping (continuous device telemetry) not described; online questionnaires alone do not meet DIGIT advanced digital phenotyping boundary used elsewhere → FALSE.	Response for Digital phenotypingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked health records Recommended	Yes	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Key Features “Data available include linked healthcare records for 25 years from the date of consent”	Response for Linked health recordsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosample types Recommended	saliva	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: How often have they been followed up? “participants were invited to provide consent to be sent a saliva sample kit to collect DNA data”	Response for Biosample typesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genotyping platform Recommended	No value held	Not published	UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: genotyping array / sequencing platform not named in cohort profile excerpts on file; NULL.	Response for Genotyping platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging modalities Recommended	No value held	Not published	UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 NULL: has_imaging_data=FALSE → imaging_modalities NULL.	Response for Imaging modalitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Mental health measures Recommended	PCL-C, EQ-5D, GPPAQ	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: What has been measured? “General Practice physical activity questionnaire (GPPAQ), EQ-5D and the post-traumatic stress disorder checklist—civilian version (PCL-C).”	Response for Mental health measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data subcategories

Structured modality and subcategory rows used alongside the high-level data-type flags.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Data subcategories Recommended List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.	No value held	No source yet	No citation linked to this field yet.	Response for Data subcategoriesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Data subcategories

Recommended

List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Consent and use permissions

Specific use permissions separate from the 3D consent-level axis.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent and use permissions Recommended Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.	No value held	No source yet	No citation linked to this field yet.	Response for Consent and use permissionsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Consent and use permissions

Recommended

Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Access pathways

One or more routes by which researchers can request or analyse data.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Access pathways Recommended Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.	No value held	No source yet	No citation linked to this field yet.	Response for Access pathwaysAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Access pathways

Recommended

Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Within-cohort coverage

Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Within-cohort coverage metrics Recommended Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.	No value held	No source yet	No citation linked to this field yet.	Response for Within-cohort coverage metricsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Within-cohort coverage metrics

Recommended

Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Linkage and access

Field	Current value	Evidence	Source evidence	Response	Notes / correction
NHS linkage Recommended	Yes	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: What has been measured? “participants gave permission to use data from their EHRs for a period of 25 years from the date of consent” UK NHS electronic healthcare records context in cohort profile → has_nhs_linkage=TRUE for hospital-centred NHS care records (conservative interpretation).	Response for NHS linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GP linkage Recommended	No	Not published	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 FALSE: cohort profile text reviewed for this pass does not explicitly assert primary-care GP record linkage as a separate stream; NHS EHR permission described generically → conservative FALSE for has_gp_linkage.	Response for GP linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Death registry linkage Recommended	No	Not published	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 FALSE: no ONS mortality / death registry linkage named in excerpts used for this population pass.	Response for Death registry linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Education linkage Recommended	No	Not published	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 FALSE: no education/DfE linkage named in excerpts used for this population pass.	Response for Education linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access mechanism Recommended	collaboration	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Can I get hold of the data? “Applications to access the resource will be assessed for consistency with the data access policy by the Scientific Committee” Governed application / collaboration pathway → data_access_mechanism=collaboration.	Response for Data access mechanismAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TRE platform Recommended	No value held	Not published	UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: funding mentions BREATHE/HDR UK partnership but cohort profile does not name a single applicant-facing TRE product for UK-REACH extracts; NULL.	Response for TRE platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data dictionary URL Recommended	https://www.uk-reach.org/data-dictionary	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: What has been measured? “additional information on the questions asked, response options and question sources can be found in the UK-REACH data dictionary (https://www.uk-reach.org/data-dictionary).”	Response for Data dictionary URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access timeline (days) Recommended	No value held	Not published	UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: no median application-to-access days cited in sources on file; NULL.	Response for Data access timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access cost Recommended	No value held	Not published	UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: no fee schedule captured in sources on file; NULL.	Response for Data access costAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Participant profile and dates

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Age distribution Recommended	65+: 0.03; <25: 0.03; 25-34: 0.23; 35-44: 0.25; 45-54: 0.27; 55-64: 0.18	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Table 3 “\| <25 \| 3 \| 6 \|” JSON keys encode Table 3 age band percentages for UK-REACH cohort column (full table transcribed in cohort INSERT).	Response for Age distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Sex distribution Recommended	male: 0.246; female: 0.752; prefer_not_to_answer: 0.001; prefer_alternative_term: 0.001	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Table 3 — Sex (%) “\| Male \| 24.6 \| 23 \|” Sex JSON uses Table 3 UK-REACH cohort male/female percentages plus small prefer-not rows as in table.	Response for Sex distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ethnicity distribution Recommended	asian: 0.172; black: 0.039; mixed: 0.037; other: 0.019; white: 0.611; prefer_not_or_missing: 0.123	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Table 3 — Ethnicity (%) “\| White \| 61.1 \| 77.9 \|” Ethnicity JSON transcribes Table 3 UK-REACH cohort ethnicity percentages including prefer-not/Not available row.	Response for Ethnicity distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Smoking status distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Smoking status distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Median age Recommended	44.0	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Key Features “aged 16–89 years (mean age: 44)” median_age field populated with published mean age 44.0 as central tendency proxy where median not reported separately.	Response for Median ageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent female Recommended	75.20	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Table 3 — Sex (%) “\| Female \| 75.2 \| 77 \|” Uses UK-REACH cohort column female percentage.	Response for Percent femaleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent non-white Recommended	26.70	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Key Features “26.7% of the UK-REACH cohort reporting a non-White ethnicity compared with 22.3% of the NHS workforce.”	Response for Percent non-whiteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	national	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Key Features “A total of 17 891 HCWs aged 16–89 years (mean age: 44) have been recruited from across the UK via all major healthcare regulators” UK-wide recruitment → geographic_coverage=national.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Follow-up duration Recommended	Planned questionnaire waves every 6 months to 2025 (per cohort profile); EHR linkage up to 25 years from consent	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: How often have they been followed up? + Why was the cohort set up? “Additional follow-up surveys have been planned for every 6 months until 2025” Combined with Key Features sentence on 25-year healthcare record linkage window from consent.	Response for Follow-up durationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Last data collection date Recommended	No value held	Not published	UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: no single last_data_collection_date published for all streams; NULL.	Response for Last data collection dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment start date Recommended	4 Dec 2020	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Who is in the cohort? “Recruitment to the cohort began on 4 December 2020 and continued until 28 February 2021.”	Response for Recruitment start dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment end date Recommended	28 Feb 2021	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Who is in the cohort? “continued until 28 February 2021.”	Response for Recruitment end dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis areas

Mental health diagnosis areas represented in this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis area: Major depressive disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Major depressive disorder · Mood Disorders	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 “anxiety, depression and post-traumatic stress.” Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Why was the cohort set up? “poor mental health outcomes such as anxiety, depression and post-traumatic stress.” Major depressive disorder area (id 5) included as depression outcome family explicitly referenced in cohort rationale. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: NULL. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: NULL.	Response for Diagnosis area: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: PTSD Recommended Confirm this diagnosis area applies and estimated N if shown.	PTSD · Trauma-Related	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 “post-traumatic stress disorder checklist—civilian version (PCL-C)” Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 “post-traumatic stress disorder checklist—civilian version (PCL-C)” PTSD diagnosis area (id 12) linked because PCL-C is named in questionnaire battery. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: no diagnosis-specific case counts published; estimated_n NULL. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: prevalence_rate NULL without diagnosis-specific numerators.	Response for Diagnosis area: PTSDAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Transdiagnostic (anxiety-depression) Recommended Confirm this diagnosis area applies and estimated N if shown.	Transdiagnostic (anxiety-depression) · Transdiagnostic	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 “\| Physical and mental health, wellbeing \|” Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Table 4 “\| Physical and mental health, wellbeing \|” Transdiagnostic anxiety–depression (id 32) used as umbrella for repeated wellbeing / mental health questionnaire domains without disease-register ascertainment. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: NULL. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: NULL.	Response for Diagnosis area: Transdiagnostic (anxiety-depression)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Long COVID neuropsychiatric Recommended Confirm this diagnosis area applies and estimated N if shown.	Long COVID neuropsychiatric · Other	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 “\| Long COVID \|” Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Table 4 “\| Long COVID \|” Long COVID neuropsychiatric diagnosis area (id 33) linked from follow-up questionnaire topic row. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: NULL. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: NULL.	Response for Diagnosis area: Long COVID neuropsychiatricAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Linked sites

Sites contributing participants or data to this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked site: NIHR Nottingham Biomedical Research Centre Recommended	NIHR Nottingham Biomedical Research Centre · East Midlands	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: UK-REACH Collaborative group “Laura Nellums (University of Nottingham)” Site 10 = NIHR Nottingham BRC as named university collaborator. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: NULL.	Response for Linked site: NIHR Nottingham Biomedical Research CentreAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked site: NIHR Leicester Biomedical Research Centre Recommended	NIHR Leicester Biomedical Research Centre · East Midlands	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: Corresponding author “Department of Infection and HIV Medicine, Leicester Royal Infirmary, Leicester, LE1 5WW, UK. E-mail: manish.pareek@leicester.ac.uk” Site 64 = NIHR Leicester BRC host geography for coordinating team. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: no Leicester-only participant count in sources on file; local_n NULL.	Response for Linked site: NIHR Leicester Biomedical Research CentreAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked site: NIHR University College London Hospitals Biomedical Research Centre Recommended	NIHR University College London Hospitals Biomedical Research Centre · London	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: UK-REACH Collaborative group “I Chris McManus (University College London), Katherine Woolf (University College London), Ibrahim Akubakar (University College London)” Site 5 = NIHR UCLH BRC / UCL partnership locus named on collaborative author list. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: NULL.	Response for Linked site: NIHR University College London Hospitals Biomedical Research CentreAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked site: NIHR Oxford Health Biomedical Research Centre Recommended	NIHR Oxford Health Biomedical Research Centre · South East England	Field-cited	Cohort Profile: UK-REACH (Int J Epidemiol 2023; PMC9452183) https://doi.org/10.1093/ije/dyac171 Section: UK-REACH Collaborative group “Amit Gupta (Oxford University Hospitals)” Site 2 = NIHR Oxford Health BRC / Oxford Health NHS FT footprint as closest seeded Oxford mental-health research infrastructure anchor for named Oxford collaborator. UK-REACH prospective longitudinal cohort protocol (BMJ Open 2021; PMC8450967) https://doi.org/10.1136/bmjopen-2021-050647 UNSOURCEABLE: NULL.	Response for Linked site: NIHR Oxford Health Biomedical Research CentreAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	ai_inferred	Internal	Internal catalogue field	—	—
Last verified Recommended	16 Apr 2026	Internal	Internal catalogue field	—	—
Data source Recommended	Populated Apr 2026 from Bryant et al. 2023 Int J Epidemiol cohort profile (PMC9452183; doi:10.1093/ije/dyac171), Woolf et al. 2021 BMJ Open protocol (doi:10.1136/bmjopen-2021-050647), and UK-REACH website (https://www.uk-reach.org/).	Internal	Internal catalogue field	—	—