Cohort validation pack

UK LLC

UK Longitudinal Linkage Collaboration (UK LLC)

Generated 6 Oct 2026, 10:37 · ID 66

AI inferred

Last verified: 16/04/2026

Instructions for reviewers

Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Summary of how well fields in this pack are linked to evidence.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	50 of 74 reviewable fields are cited to a source (68%) · 7 with no source yet · 17 searched — not published · 22 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and ownership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Short name Required	UK LLC	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “UK Longitudinal Linkage Collaboration University of Bristol” Page: https://ukllc.ac.uk/about-us Public acronym UK LLC is used as the short cohort name; footer text includes the spelled-out collaboration name.	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Full name Required	UK Longitudinal Linkage Collaboration (UK LLC)	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “UK Longitudinal Linkage Collaboration (UK LLC): The National Trusted Research Environment for Longitudinal Research” Page: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11931487/fullTextXML	Response for Full nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Managing organisation Recommended	University of Bristol and University of Edinburgh (UK LLC consortium, with UCL, SeRP UK, Swansea University, University of Leicester, City St George's University of London and Population Research UK)	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “UK LLC is run by the Universities of Bristol and Edinburgh, in partnership with UCL, SeRP UK, Swansea University, City St George’s, University of London, University of Leicester and Population Research UK.” Page: https://ukllc.ac.uk/about-us	Response for Managing organisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Primary site Recommended	NIHR Bristol Biomedical Research Centre (site #8)	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “We are led by the Universities of ” Page: https://ukllc.ac.uk/about-us primary_site_id=8 (NIHR Bristol BRC / University of Bristol partnership) because Bristol is named first among the lead universities.	Response for Primary siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://ukllc.ac.uk/	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “https://ukllc.ac.uk/” Page: https://ukllc.ac.uk/about-us	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catalogue of Mental Health Measures URL Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Catalogue of Mental Health Measures URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact name Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: public pages route enquiries via applications portal and access email rather than naming a single accountable contact in captured HTML.	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	access@ukllc.ac.uk	Field-cited	UK LLC — Researcher application portal https://apply.ukllc.ac.uk/ “access@ukllc.ac.uk” Page: https://apply.ukllc.ac.uk/	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Summary and status

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Description Required	UK LLC is the national Trusted Research Environment (TRE) for longitudinal research in the UK: it links anonymised participant data from 20+ longitudinal population studies (LPS) to NHS and other records within ISO 27001–certified, Digital Economy Act–accredited secure infrastructure hosted on SeRP UK at Swansea University, with trusted third-party linkage processing. Researchers apply through a single governance route to study public-good questions using pooled LPS data systematically linked to diverse health and non-health records.	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 Section: Conclusions “UK LLC enables researchers to interrogate pooled LPS participant data that are systematically linked to diverse records.” UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “At UK LLC, we have established data and governance pipelines to link anonymised Longitudinal Population Study participant data to their health, administrative socio-economic, demographic and place-based data.” Page: https://ukllc.ac.uk/about-us	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N Required	400,000	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “We provide secure access to our Trusted Research Environment containing more than 400,000 participant records from Longitudinal Population Studies (LPS) across the four UK nations.” Page: https://ukllc.ac.uk/about-us total_n set to 400000 (approximate) from the published participant record count.	Response for Total NAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N qualifier Recommended	approximate	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “more than 400,000 participant records” Page: https://ukllc.ac.uk/about-us total_n_qualifier=approximate because the website uses a rounded lower bound wording.	Response for Total N qualifierAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Year established Recommended	2020	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “UK LLC originated in 2020 as part of the COVID-19 Longitudinal Health and Wellbeing National Core Study” Page: https://ukllc.ac.uk/about-us	Response for Year establishedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active cohort Recommended	Yes	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “We provide secure access to our Trusted Research Environment containing more than 400,000 participant records” Page: https://ukllc.ac.uk/about-us is_active=TRUE: live national service language.	Response for Active cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ongoing recruitment Recommended	No	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 Section: Abstract Objectives “UK LLC supports longitudinal research by providing record linkage and TRE services.” ongoing_recruitment=FALSE: entity is an infrastructure/TRE service rather than a single study recruiting participants.	Response for Ongoing recruitmentAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Refreshed cohort Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “for the extract to be refreshed on a timely basis to ensure an optimal resource for researchers” is_refreshed=TRUE: protocol describes timely refresh of linked extracts.	Response for Refreshed cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recontact success rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: not a single-recruitment cohort metric for the TRE infrastructure row.	Response for Recontact success rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Retention rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: retention differs by partner LPS; not expressed as one UK LLC figure.	Response for Retention rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Published references Recommended	10.23889/ijpds.v10i1.2468, 10.23889/ijpds.v7i3.2046	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “10.23889/ijpds.v10i1.2468” published_references includes the 2025 protocol DOI; second DOI 10.23889/ijpds.v7i3.2046 is the earlier UK LLC community paper also cited in programme materials.	Response for Published referencesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Notes Recommended	DIGIT models UK LLC as a national data resource (not a single-recruitment study). Participant counts and modalities depend on which LPS have joined and which linkages permissions allow; figures and flags follow the 2025 IJPDS protocol and the UK LLC public website as of Apr 2026. Commercial/for-profit use is handled separately (see apply.ukllc.ac.uk).	Field-cited	UK LLC — Researcher application portal https://apply.ukllc.ac.uk/ “UK LLC does not currently support for-profit research and we ask any interested commercial users to get in touch via email to access@ukllc.ac.uk before submitting an Expression of Interest.” Page: https://apply.ukllc.ac.uk/ Notes capture commercial access caveat alongside consortium scope from the About page. UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “Our TRE is hosted by Swansea University’s Secure eResearch Platform (SeRP UK)” Page: https://ukllc.ac.uk/about-us	Response for NotesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

3D cohort mapping

Consent, characterisation, and data availability axes used on the cohort map.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent level (axis) Required	3 — Broad consent (recontactable for future studies)	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 Section: Abstract Methods “Researchers can apply to access the TRE via an approach that fulfils the needs of the LPS, the linked data owners and includes a review by public contributors.” Step1: controlled TRE access to person-level linked data for approved projects implies controlled identifiability within the secure environment (YES). Step2: access is framed around LPS permissions and linked data owner requirements rather than unconsented S251-only NHS reuse as the sole basis (NO for forcing Level 2). Step3: LPS participants participate in longitudinal studies for research use with governance including public contributors (YES for broad/research-engaged consent). Step4: no statement that every participant has protocol-specific interventional trial consent within UK LLC itself (NO). -> consent_level=3.	Response for Consent level (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Characterisation depth (axis) Required	3 — Multi-domain MH characterisation	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Specific COVID-19 data collections (questionnaires and assayed biological data)” characterisation_depth=3: pooled LPS include systematic questionnaires and biological/omic measures across domains, combined with linked NHS records, exceeding routine EHR-only (Level 1) and single-scale screening (Level 2); protocol does not establish SCID/MINI/SCAN plus active refresh as a uniform standard for every participant (not Level 4).	Response for Characterisation depth (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data availability (axis) Required	4 — Multi-modal	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “image data (e.g. brain or organ MRIs, DEXA bone density scans, retina images) or wider smart data (e.g. sensor data from wearable devices)” DERIVED: hasResearch TRUE (questionnaires + linked NHS records), hasBiological TRUE (genomic/omic/biosample classes quoted on other rows), hasAdvanced TRUE (imaging + wearable sensor classes quoted here) -> data_availability=4 per data-dictionary.md.	Response for Data availability (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cohort map group (derived) Recommended	Group 4	Internal	Internal catalogue field	—	—
Population type Recommended	Data resource	Not published	DIGIT Cohort Portfolio Review — population type and engagement classification (Aug 2026) Classified data_resource in the DIGIT cohort portfolio review (Aug 2026). National trusted research environment linking longitudinal population studies — infrastructure rather than a recruited cohort.	Response for Population typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Industry engagement status Recommended	Unknown	Not published	Searched — not published UNSOURCEABLE: industry engagement status is an organisational property of the custodian and is not publicly documented; default 'unknown' pending a cohort-owner meeting.	Response for Industry engagement statusAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Parent cohort / programme Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Parent cohort / programmeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TWiCs eligible Recommended	No	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Researchers can apply to access the TRE via an approach that fulfils the needs of the LPS, the linked data owners and includes a review by public contributors.” twics_eligible=FALSE: access is project-governed within a TRE rather than TWiCs-style embedded randomisation for all participants.	Response for TWiCs eligibleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data modalities

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Questionnaire / interview Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Specific COVID-19 data collections (questionnaires and assayed biological data)” TRUE: pooled LPS include questionnaire collections within the TRE data model.	Response for Questionnaire / interviewAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cognitive testing Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “objective physical and cognitive capability and visual health in an ageing population of men and women in Norfolk (EPIC-Norfolk 3). Int J Epidemiol. 2013;43(4):1063-72. 10.1093/ije/dyt086” TRUE: protocol reference list includes cohort profile exemplars with objective cognitive capability measures among participating LPS-linked data classes.	Response for Cognitive testingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Physical measures Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “objective physical and cognitive capability and visual health” TRUE: objective physical capability measures are explicitly exemplified.	Response for Physical measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosamples Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Existing assayed biological information (e.g. blood group type, biomarkers such as serology)” TRUE: assayed biological specimens/information are within scope of hosted LPS-linked data classes.	Response for BiosamplesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genomic data Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Derived genetic, metabolomic, proteomic and epigenetic information” TRUE: derived genetic information is explicitly listed.	Response for Genomic dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Omics Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Derived genetic, metabolomic, proteomic and epigenetic information” TRUE: metabolomic/proteomic/epigenetic derivatives are explicitly listed beyond genomics alone.	Response for OmicsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “image data (e.g. brain or organ MRIs, DEXA bone density scans, retina images)” TRUE: research image modalities are explicitly listed as in-scope de-identified data classes.	Response for ImagingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Wearable / sensor Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “sensor data from wearable devices” TRUE: wearable sensor data are explicitly listed as in-scope smart data.	Response for Wearable / sensorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Digital phenotyping Recommended	No	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “sensor data from wearable devices” FALSE per data-dictionary.md digital phenotyping definition: protocol lists wearable sensor streams but does not evidence passive smartphone metadata phenotyping (GPS/screen-time/call logs) as a distinct hosted class; conservative FALSE.	Response for Digital phenotypingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked health records Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 Section: Abstract Results “participants are linked to their National Health Service (NHS) England, NHS Wales and place-based records” TRUE: systematic NHS record linkage is a core UK LLC outcome.	Response for Linked health recordsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosample types Recommended	No value held	Not published	NULL: assayed biological information is evidenced at the resource level but specific biosample type vocabulary is not enumerated as a fixed array in captured sources.	Response for Biosample typesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genotyping platform Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: genomics exists across partner studies but no single platform string applies to the pooled resource row.	Response for Genotyping platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging modalities Recommended	structural_mri, dexa, retinal	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “brain or organ MRIs, DEXA bone density scans, retina images” imaging_modalities ARRAY maps quoted modality examples to controlled tokens used elsewhere in DIGIT seeds.	Response for Imaging modalitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Mental health measures Recommended	Linked NHS mental health service contacts and community mental health care records (where permissions allow), Validated mental health measures from partner longitudinal studies (study-dependent questionnaires and assessments), Derived phenotypes from linked routine records alongside LPS self-report and clinical measures	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Mental health data about people in contact with community mental health care services” mental_health_measures ARRAY summarises explicit NHS mental health service-linked data classes plus LPS instruments described elsewhere in the protocol.	Response for Mental health measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data subcategories

Structured modality and subcategory rows used alongside the high-level data-type flags.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Data subcategories Recommended List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.	No value held	No source yet	No citation linked to this field yet.	Response for Data subcategoriesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Data subcategories

Recommended

List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Consent and use permissions

Specific use permissions separate from the 3D consent-level axis.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent and use permissions Recommended Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.	No value held	No source yet	No citation linked to this field yet.	Response for Consent and use permissionsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Consent and use permissions

Recommended

Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Access pathways

One or more routes by which researchers can request or analyse data.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Access pathways Recommended Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.	No value held	No source yet	No citation linked to this field yet.	Response for Access pathwaysAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Access pathways

Recommended

Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Within-cohort coverage

Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Within-cohort coverage metrics Recommended Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.	No value held	No source yet	No citation linked to this field yet.	Response for Within-cohort coverage metricsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Within-cohort coverage metrics

Recommended

Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Linkage and access

Field	Current value	Evidence	Source evidence	Response	Notes / correction
NHS linkage Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Secondary care data including hospital inpatients (includes intensive care and maternity), outpatients and accident and emergency records” TRUE: NHS secondary care extracts are explicitly within the linked health data scope.	Response for NHS linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GP linkage Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Primary care data” TRUE: primary care data are explicitly listed among linked NHS-linked classes.	Response for GP linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Death registry linkage Recommended	Yes	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Mortality and cancer registry records” TRUE: mortality registry records are explicitly listed.	Response for Death registry linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Education linkage Recommended	No	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 Section: Abstract Results “with work ongoing to link to NHS Scotland and non-health administrative records, including Department for Work and Pensions and His Majesty’s (HM) Revenue and Customs.” has_education_linkage=FALSE: abstract results name DWP/HMRC as non-health administrative linkage priorities but do not name education/DfE linkage as an implemented UK LLC data class in this snapshot.	Response for Education linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access mechanism Recommended	tre	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Researchers can apply to access the TRE via an approach that fulfils the needs of the LPS, the linked data owners and includes a review by public contributors.” data_access_mechanism=tre.	Response for Data access mechanismAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TRE platform Recommended	UK LLC Trusted Research Environment (SeRP UK; Swansea University hosting)	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “Our TRE is hosted by Swansea University’s Secure eResearch Platform (SeRP UK)” Page: https://ukllc.ac.uk/about-us tre_platform string also reflects UK LLC branding as the national TRE service.	Response for TRE platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data dictionary URL Recommended	https://guidebook.ukllc.ac.uk/docs/welcome.html	Field-cited	HDR UK — UK Longitudinal Linkage Collaboration (organisational overview) https://www.hdruk.ac.uk/organisations/the-uk-longitudinal-linkage-collaboration-uk-llc/ “https://guidebook.ukllc.ac.uk/docs/welcome.html” Page: https://www.hdruk.ac.uk/organisations/the-uk-longitudinal-linkage-collaboration-uk-llc/	Response for Data dictionary URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access timeline (days) Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no single integer turnaround published on reviewed pages.	Response for Data access timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access cost Recommended	Free to access for any ONS-accredited researcher in the UK with a public-good research question (per HDR UK organisational page; commercial enquiries directed to access@ukllc.ac.uk)	Field-cited	HDR UK — UK Longitudinal Linkage Collaboration (organisational overview) https://www.hdruk.ac.uk/organisations/the-uk-longitudinal-linkage-collaboration-uk-llc/ “UK LLC is currently free to access to any ONS accredited researcher in the UK with a research question in the public good.” Page: https://www.hdruk.ac.uk/organisations/the-uk-longitudinal-linkage-collaboration-uk-llc/	Response for Data access costAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Participant profile and dates

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Age distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no single-cohort Table 1 demographics for the pooled TRE resource in captured files.	Response for Age distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Sex distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: as age_distribution.	Response for Sex distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ethnicity distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: as age_distribution.	Response for Ethnicity distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Smoking status distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Smoking status distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Median age Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: pooled multi-LPS TRE; no single median age published on reviewed pages.	Response for Median ageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent female Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: pooled multi-LPS TRE.	Response for Percent femaleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent non-white Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: pooled multi-LPS TRE.	Response for Percent non-whiteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	national	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “participant records from Longitudinal Population Studies (LPS) across the four UK nations” Page: https://ukllc.ac.uk/about-us geographic_coverage=national (four-nation LPS coverage).	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Follow-up duration Recommended	>10 years	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “This includes some of the earliest LPS established, with decades of self-reported and clinical data.” Page: https://ukllc.ac.uk/about-us followup_duration=>10 years captures multi-decade LPS follow-up described publicly.	Response for Follow-up durationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Last data collection date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: rolling linked extracts across many LPS.	Response for Last data collection dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment start date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: not applicable as a single-study open/close recruitment window.	Response for Recruitment start dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment end date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: not applicable as a single-study open/close recruitment window.	Response for Recruitment end dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis areas

Mental health diagnosis areas represented in this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis area: Schizophrenia Recommended Confirm this diagnosis area applies and estimated N if shown.	Schizophrenia · Psychotic Disorders	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Mental health data about people in contact with community mental health care services” Psychotic disorders fall within NHS mental health service contacts linked where permissions allow.	Response for Diagnosis area: SchizophreniaAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Major depressive disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Major depressive disorder · Mood Disorders	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Mental health data about people in contact with community mental health care services” Major depressive disorder is covered within NHS mental health service-linked records plus CMD LPS measures where collected.	Response for Diagnosis area: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Generalised anxiety disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Generalised anxiety disorder · Anxiety Disorders	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “Mental health data about people in contact with community mental health care services” Anxiety disorders are in scope via the same NHS mental health service data class and CMD-focused LPS instruments.	Response for Diagnosis area: Generalised anxiety disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Transdiagnostic (anxiety-depression) Recommended Confirm this diagnosis area applies and estimated N if shown.	Transdiagnostic (anxiety-depression) · Transdiagnostic	Field-cited	Boyd A et al. UK LLC national TRE protocol (IJPDS 2025) — Europe PMC fullTextXML https://doi.org/10.23889/ijpds.v10i1.2468 “UK LLC enables researchers to interrogate pooled LPS participant data that are systematically linked to diverse records.” Transdiagnostic CMD / multi-morbidity analyses are an explicit use case for pooled longitudinal linkage.	Response for Diagnosis area: Transdiagnostic (anxiety-depression)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Linked sites

Sites contributing participants or data to this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked site: NIHR Leicester Biomedical Research Centre Recommended	NIHR Leicester Biomedical Research Centre · East Midlands	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “University of Leicester” Page: https://ukllc.ac.uk/about-us Site 64 (Leicester BRC) matches the University of Leicester / Leicester NHS partnership named as a UK LLC partner.	Response for Linked site: NIHR Leicester Biomedical Research CentreAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked site: NIHR University College London Hospitals Biomedical Research Centre Recommended	NIHR University College London Hospitals Biomedical Research Centre · London	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “in partnership with University College London” Page: https://ukllc.ac.uk/about-us Site 5 (UCLH BRC / UCL partnership) is used as the closest DIGIT site anchor for UCL named as a consortium partner.	Response for Linked site: NIHR University College London Hospitals Biomedical Research CentreAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked site: University of Edinburgh Recommended	University of Edinburgh · Scotland	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “UK LLC is run by the Universities of Bristol and Edinburgh, in partnership with UCL, SeRP UK, Swansea University, City St George’s, University of London, University of Leicester and Population Research UK.” Page: https://ukllc.ac.uk/about-us Site 12 (University of Edinburgh) matches Edinburgh named as co-lead alongside Bristol in the footer governance paragraph.	Response for Linked site: University of EdinburghAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked site: NIHR Bristol Biomedical Research Centre Recommended	NIHR Bristol Biomedical Research Centre · South West England	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “We are led by the Universities of ” Page: https://ukllc.ac.uk/about-us Site 8 (NIHR Bristol BRC / University of Bristol partnership) matches the first-named lead institution.	Response for Linked site: NIHR Bristol Biomedical Research CentreAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked site: Swansea University Recommended	Swansea University · Wales	Field-cited	UK Longitudinal Linkage Collaboration — About us https://ukllc.ac.uk/about-us “Our TRE is hosted by Swansea University’s Secure eResearch Platform (SeRP UK)” Page: https://ukllc.ac.uk/about-us Site 22 (Swansea University) matches the documented SeRP UK hosting organisation.	Response for Linked site: Swansea UniversityAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	ai_inferred	Internal	Internal catalogue field	—	—
Last verified Recommended	16 Apr 2026	Internal	Internal catalogue field	—	—
Data source Recommended	Populated Apr 2026 from ukllc.ac.uk (about us), apply.ukllc.ac.uk, hdruk.ac.uk UK LLC organisational page, Europe PMC full-text XML for Boyd et al. 2025 IJPDS (PMC11931487 / DOI 10.23889/ijpds.v10i1.2468), ClinicalTrials.gov API v2, ISRCTN XML API, in-repo docs/data-dictionary.md and docs/data-population-plan.md snapshots.	Internal	Internal catalogue field	—	—