Cohort validation pack
NBR-MH
NIHR BioResource for Mental Health
Generated 6 Oct 2026, 10:36 · ID 37
Last verified: 16/04/2026
Instructions for reviewers
- Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
- Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
- Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.
Overview
91
Total fields
58
Field-cited
0
Whole-record source only
4
AI-inferred, no source yet
24
Searched — not published
26
No value held
28
Needs review
Source coverage
Summary of how well fields in this pack are linked to evidence.
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Field-level source coverage Optional | 58 of 86 reviewable fields are cited to a source (67%) · 4 with no source yet · 24 searched — not published · 26 with no value held | Computed | No citation linked to this field yet. | No response selected | No notes |
Identity and ownership
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Short name Required | NBR-MH | Field-cited |
| No response selected | No notes |
Full name Required | NIHR BioResource for Mental Health | Field-cited |
| No response selected | No notes |
Managing organisation Recommended | NIHR BioResource | Field-cited |
| No response selected | No notes |
Primary site Recommended | NIHR Maudsley Biomedical Research Centre (site #1) | Field-cited |
| No response selected | No notes |
Website URL Recommended | https://www.bioresource.nihr.ac.uk/centres-programmes/mental-health-bioresource/ | Field-cited |
| No response selected | No notes |
Catalogue of Mental Health Measures URL Recommended | No value held | No source yet | No citation linked to this field yet. | No response selected | No notes |
Contact name Recommended | No value held | Not published |
| No response selected | No notes |
Contact email Recommended | No value held | Not published |
| No response selected | No notes |
Summary and status
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Description Required | UK umbrella for the NIHR Mental Health BioResource: GLAD (depression/anxiety), EDGI (eating disorders), SMILE (severe mental illness), plus related initiatives described on the BioResource mental health programme page. Participants join consented panels with questionnaires and saliva/blood samples for genetic research and can be recontacted for further ethically approved studies. | Field-cited |
| No response selected | No notes |
Total N Required | 104,000 | Field-cited |
| No response selected | No notes |
Total N qualifier Recommended | approximate | Field-cited |
| No response selected | No notes |
Year established Recommended | 2018 | Field-cited |
| No response selected | No notes |
Active cohort Recommended | Yes | Field-cited |
| No response selected | No notes |
Ongoing recruitment Recommended | Yes | Field-cited |
| No response selected | No notes |
Refreshed cohort Recommended | Yes | Field-cited |
| No response selected | No notes |
Recontact success rate Recommended | No value held | Not published |
| No response selected | No notes |
Retention rate Recommended | No value held | Not published |
| No response selected | No notes |
Published references Recommended | doi:10.1016/j.brat.2019.103503 | Field-cited |
| No response selected | No notes |
Notes Recommended | total_n≈104k sums GLAD (91,000+ consented) + EDGI (13,000 consented, figures as of June 2024 on the Mental Health BioResource page); SMILE targets up to 2,000 participants with SMI separately (not added into total_n to avoid double-counting). `group_label=group_2`: dictionary typical band for consent 3 + characterisation 2–3 + data availability 2–3 matches this umbrella (GLAD is also named under group_2 examples); BioResource for Mental Health additionally appears as a group_1 example — borderline call documented here per assignment rule. | Field-cited |
| No response selected | No notes |
3D cohort mapping
Consent, characterisation, and data availability axes used on the cohort map.
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Consent level (axis) Required | 3 — Broad consent (recontactable for future studies) | Field-cited |
| No response selected | No notes |
Characterisation depth (axis) Required | 2 — Standardised MH instruments | Field-cited |
| No response selected | No notes |
Data availability (axis) Required | 3 — Adds biological specimens/molecular data | Field-cited |
| No response selected | No notes |
Cohort map group (derived) Recommended | Group 3 | Internal | Internal catalogue field | — | — |
Population type Recommended | Network / umbrella | Not published |
| No response selected | No notes |
Industry engagement status Recommended | Established access process | Not published |
| No response selected | No notes |
Parent cohort / programme Recommended | No value held | No source yet | No citation linked to this field yet. | No response selected | No notes |
TWiCs eligible Recommended | No | Field-cited |
| No response selected | No notes |
Data modalities
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Questionnaire / interview Recommended | Yes | Field-cited |
| No response selected | No notes |
Cognitive testing Recommended | No | Field-cited |
| No response selected | No notes |
Physical measures Recommended | No | Field-cited |
| No response selected | No notes |
Biosamples Recommended | Yes | Field-cited |
| No response selected | No notes |
Genomic data Recommended | Yes | Field-cited |
| No response selected | No notes |
Omics Recommended | No | Field-cited |
| No response selected | No notes |
Imaging Recommended | No | Field-cited |
| No response selected | No notes |
Wearable / sensor Recommended | No | Field-cited |
| No response selected | No notes |
Digital phenotyping Recommended | No | Field-cited |
| No response selected | No notes |
Linked health records Recommended | No | Field-cited |
| No response selected | No notes |
Biosample types Recommended | saliva, blood | Field-cited |
| No response selected | No notes |
Genotyping platform Recommended | No value held | Not published |
| No response selected | No notes |
Imaging modalities Recommended | No value held | Not published | No response selected | No notes | |
Mental health measures Recommended | No value held | Not published |
| No response selected | No notes |
Data subcategories
Structured modality and subcategory rows used alongside the high-level data-type flags.
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Data modality: Blood sample Recommended Confirm this row is correctly typed as a category marker, named instrument/interview, biospecimen type, assay/data product, imaging modality, sensor stream, or linked-record type; add missing named instruments/sample types where known. | available · biosamples · biospecimen type · parent: Biospecimen collection · SMILE BioResource asks volunteers for blood or saliva samples | Field-cited |
| No response selected | No notes |
Data modality: Saliva sample Recommended Confirm this row is correctly typed as a category marker, named instrument/interview, biospecimen type, assay/data product, imaging modality, sensor stream, or linked-record type; add missing named instruments/sample types where known. | available · biosamples · biospecimen type · parent: Biospecimen collection · GLAD saliva sample kits | Field-cited |
| No response selected | No notes |
Data modality: Biospecimen collection Recommended Confirm this row is correctly typed as a category marker, named instrument/interview, biospecimen type, assay/data product, imaging modality, sensor stream, or linked-record type; add missing named instruments/sample types where known. | available · biosamples · category marker · Saliva and blood samples across programme components | Field-cited |
| No response selected | No notes |
Data modality: Genotyping array Recommended Confirm this row is correctly typed as a category marker, named instrument/interview, biospecimen type, assay/data product, imaging modality, sensor stream, or linked-record type; add missing named instruments/sample types where known. | available on application · genomics · derived genomic data · Genetic data available through NIHR BioResource governance | Field-cited |
| No response selected | No notes |
Data modality: Questionnaire / interview data Recommended Confirm this row is correctly typed as a category marker, named instrument/interview, biospecimen type, assay/data product, imaging modality, sensor stream, or linked-record type; add missing named instruments/sample types where known. | available · questionnaires · category marker · Mental Health BioResource questionnaire capture | Field-cited |
| No response selected | No notes |
Consent and use permissions
Specific use permissions separate from the 3D consent-level axis.
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Consent/use: Biosample research use Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ. | permitted · biosample use · local operational permission · Participants with samples · Participants provide saliva or blood samples for genetic research. | Field-cited |
| No response selected | No notes |
Consent/use: Industry / commercial research considered Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ. | permitted · commercial use · local operational permission · Consented participants · NIHR BioResource home page states support for industry researchers. | Field-cited |
| No response selected | No notes |
Consent/use: Data sharing permitted Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ. | restricted · data sharing · local operational permission · Approved researchers · Access to participant panels and data is managed by NIHR BioResource governance. | Field-cited |
| No response selected | No notes |
Consent/use: Ethics approval required Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ. | restricted · governance · duo modifier · Commercial users · Use remains subject to BioResource governance and access approval. | Field-cited |
| No response selected | No notes |
Consent/use: Participant recontact permitted Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ. | permitted · recontact · local operational permission · Consented participants · Mental Health BioResource is explicitly re-contactable. | Field-cited |
| No response selected | No notes |
Consent/use: Health / medical / biomedical research use Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ. | permitted · research use · duo permission · DUO:0000002 · Consented participants · NIHR BioResource supports academic and clinical researchers. | Field-cited |
| No response selected | No notes |
Consent/use: Approach for trials permitted Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ. | restricted · trial approach · local operational permission · Consented participants · Recontact by genotype or phenotype supports study approach; specific trials still require approval and consent. | Field-cited |
| No response selected | No notes |
Access pathways
One or more routes by which researchers can request or analyse data.
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Access pathway: Collaboration required Recommended Confirm route, access level, environment type, DAC review, collaboration, data sharing agreement, output checking, platform, timeline, cost, URL, and whether multiple routes are possible. | available on application · access level: custodian review · environment: other · collaboration required · data sharing agreement required · NIHR BioResource · https://www.bioresource.nihr.ac.uk/ · NIHR BioResource supports researcher access to consented participant panels and associated data. | Field-cited |
| No response selected | No notes |
Access pathway: Data custodian enquiry Recommended Confirm route, access level, environment type, DAC review, collaboration, data sharing agreement, output checking, platform, timeline, cost, URL, and whether multiple routes are possible. | available on application · access level: custodian review · environment: other · data sharing agreement required · NIHR BioResource · https://www.bioresource.nihr.ac.uk/centres-programmes/mental-health-bioresource/ · Public pages identify the programme and recontactable resource; specific data access route needs custodian confirmation. | Field-cited |
| No response selected | No notes |
Within-cohort coverage
Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Within-cohort coverage metrics Recommended Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total. | No value held | No source yet | No citation linked to this field yet. | No response selected | No notes |
Linkage and access
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
NHS linkage Recommended | No | Field-cited |
| No response selected | No notes |
GP linkage Recommended | No | Field-cited |
| No response selected | No notes |
Death registry linkage Recommended | No | Field-cited |
| No response selected | No notes |
Education linkage Recommended | No | Field-cited |
| No response selected | No notes |
Data access mechanism Recommended | No value held | Not published |
| No response selected | No notes |
TRE platform Recommended | No value held | Not published |
| No response selected | No notes |
Data dictionary URL Recommended | No value held | Not published |
| No response selected | No notes |
Data access timeline (days) Recommended | No value held | Not published |
| No response selected | No notes |
Data access cost Recommended | No value held | Not published |
| No response selected | No notes |
Participant profile and dates
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Age distribution Recommended | No value held | Not published |
| No response selected | No notes |
Sex distribution Recommended | No value held | Not published |
| No response selected | No notes |
Ethnicity distribution Recommended | No value held | Not published |
| No response selected | No notes |
Smoking status distribution Recommended | No value held | No source yet | No citation linked to this field yet. | No response selected | No notes |
Median age Recommended | No value held | Not published |
| No response selected | No notes |
Percent female Recommended | No value held | Not published |
| No response selected | No notes |
Percent non-white Recommended | No value held | Not published |
| No response selected | No notes |
Geographic coverage Recommended | national | Field-cited |
| No response selected | No notes |
Follow-up duration Recommended | No value held | Not published |
| No response selected | No notes |
Last data collection date Recommended | No value held | Not published |
| No response selected | No notes |
Recruitment start date Recommended | No value held | Not published |
| No response selected | No notes |
Recruitment end date Recommended | No value held | Not published |
| No response selected | No notes |
Diagnosis areas
Mental health diagnosis areas represented in this cohort.
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Diagnosis area: Schizophrenia Recommended Confirm this diagnosis area applies and estimated N if shown. | Schizophrenia · Psychotic Disorders | Field-cited |
| No response selected | No notes |
Diagnosis area: First-episode psychosis Recommended Confirm this diagnosis area applies and estimated N if shown. | First-episode psychosis · Psychotic Disorders | Field-cited |
| No response selected | No notes |
Diagnosis area: Schizoaffective disorder Recommended Confirm this diagnosis area applies and estimated N if shown. | Schizoaffective disorder · Psychotic Disorders | Field-cited |
| No response selected | No notes |
Diagnosis area: Bipolar disorder Recommended Confirm this diagnosis area applies and estimated N if shown. | Bipolar disorder · Mood Disorders | Field-cited |
| No response selected | No notes |
Diagnosis area: Major depressive disorder Recommended Confirm this diagnosis area applies and estimated N if shown. | Major depressive disorder · Mood Disorders | Field-cited |
| No response selected | No notes |
Diagnosis area: Generalised anxiety disorder Recommended Confirm this diagnosis area applies and estimated N if shown. | Generalised anxiety disorder · Anxiety Disorders | Field-cited |
| No response selected | No notes |
Diagnosis area: Eating disorders (anorexia) Recommended Confirm this diagnosis area applies and estimated N if shown. | Eating disorders (anorexia) · Eating Disorders | Field-cited |
| No response selected | No notes |
Diagnosis area: Eating disorders (bulimia) Recommended Confirm this diagnosis area applies and estimated N if shown. | Eating disorders (bulimia) · Eating Disorders | Field-cited |
| No response selected | No notes |
Linked sites
Sites contributing participants or data to this cohort.
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Linked site: NIHR Maudsley Biomedical Research Centre Recommended | NIHR Maudsley Biomedical Research Centre · London | Field-cited |
| No response selected | No notes |
Linked site: NIHR Oxford Health Biomedical Research Centre Recommended | NIHR Oxford Health Biomedical Research Centre · South East England | Field-cited |
| No response selected | No notes |
Verification metadata
Internal catalogue status — for reference only.
| Field | Current value | Evidence | Source evidence | Response | Notes / correction |
|---|---|---|---|---|---|
Verification status Recommended | unverified | Internal | Internal catalogue field | — | — |
Last verified Recommended | 16 Apr 2026 | Internal | Internal catalogue field | — | — |
Data source Recommended | Verified Apr 2026 from NIHR BioResource Mental Health programme page, SMILE BioResource programme page, NIHR BioResource home page, GLAD About page, NIHR Maudsley BRC GLAD impact story, ClinicalTrials.gov API (Genetic Links to Anxiety and Depression query), ISRCTN XML API (NIHR BioResource mental health query), HDR UK Innovation Gateway search HTML, Elsevier DOI redirect capture for GLAD protocol DOI, Google Scholar results HTML, Dementias Platform UK homepage HTML, docs/data-dictionary.md + docs/data-population-plan.md excerpts on disk. A targeted DPUK cohort-directory keyword search previously returned HTTP 22 (no separate file saved). | Internal | Internal catalogue field | — | — |