Cohort validation pack

CPRD

Clinical Practice Research Datalink

Generated 6 Oct 2026, 10:36 · ID 23

Unverified

Instructions for reviewers

Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Summary of how well fields in this pack are linked to evidence.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	36 of 69 reviewable fields are cited to a source (52%) · 9 with no source yet · 24 searched — not published · 30 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and ownership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Short name Required	CPRD	Field-cited	CPRD Official Website https://www.cprd.com/ Section: Site branding “Clinical Practice Research Datalink” Page: https://www.cprd.com/	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Full name Required	Clinical Practice Research Datalink	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Article title “Data Resource Profile: Clinical Practice Research Datalink (CPRD)” Page: https://doi.org/10.1093/ije/dyv098	Response for Full nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Managing organisation Recommended	MHRA / NIHR	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Funding sources “The CPRD is a joint venture from the Medicines and Healthcare Regulatory Agency (MHRA) and the National Institute for Health Research (NIHR).” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/	Response for Managing organisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Primary site Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Primary siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://cprd.com/	Field-cited	CPRD Official Website https://www.cprd.com/ Section: Homepage URL “https://www.cprd.com/” Page: https://www.cprd.com/	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catalogue of Mental Health Measures URL Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Catalogue of Mental Health Measures URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact name Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No named single public contact person for CPRD cohort record across cprd.com, HDRUK pages, and profile paper.	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Generic enquiry contact exists on some CPRD pages but no stable cohort-specific contact_email field asserted in verified snippets.	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Summary and status

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Description Required	UK primary care EHR resource managed by MHRA with NIHR support. CPRD aggregates anonymised longitudinal GP records and supports approved linkage to secondary care and mortality datasets.	Field-cited	CPRD Primary Care OMOP Common Data Model March 2025 https://doi.org/10.48329/52h1-8g32 Section: Summary “The CPRD Primary Care OMOP CDM database contains longitudinal routinely-collected electronic health records (EHR) from UK primary care practices.” Page: https://www.cprd.com/doi/cprd-primary-care-omop-common-data-model-march-2025	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N Required	65,000,000	Field-cited	CPRD Official Website https://www.cprd.com/ Section: Primary care data “CPRD primary care databases contain anonymised Electronic Health Records (EHR) from over 65 million patients across the UK, including over 19 million currently registered (live) patients.” Page: https://www.cprd.com/data/primary-care-data	Response for Total NAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N qualifier Recommended	approximate	Field-cited	CPRD Official Website https://www.cprd.com/ Section: Primary care data “over 65 million patients” Page: https://www.cprd.com/data/primary-care-data Value is a rounded public statement ('over 65 million'), so qualifier=approximate per data-dictionary.	Response for Total N qualifierAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Year established Recommended	1987	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Data resource basics “Established in London in 1987” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/	Response for Year establishedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active cohort Recommended	Yes	Field-cited	CPRD Official Website https://www.cprd.com/ Section: Primary care data “CPRD works with a network of over 2,400 General Practitioner (GP) practices across the UK” Page: https://www.cprd.com/data/primary-care-data Current ongoing GP network confirms active data collection service.	Response for Active cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ongoing recruitment Recommended	No	Not published	Searched — not published UNSOURCEABLE as participant recruitment concept is not directly applicable; CPRD is an operational data service and practice onboarding is continuous.	Response for Ongoing recruitmentAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Refreshed cohort Recommended	Yes	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Frequency of data collection “Data are collected by practices and usually uploaded to the CPRD secure servers on a monthly basis.” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ Monthly uploads and ongoing data accrual satisfy refreshed/renewed definition.	Response for Refreshed cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recontact success rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No cohort-level recontact metric published in searched sources.	Response for Recontact success rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Retention rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No participant retention metric is reported for CPRD as a routine EHR service dataset.	Response for Retention rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Published references Recommended	doi:10.1093/ije/dyv098, doi:10.48329/52h1-8g32	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Citation “doi: 10.1093/ije/dyv098” Page: https://doi.org/10.1093/ije/dyv098 CPRD Primary Care OMOP Common Data Model March 2025 https://doi.org/10.48329/52h1-8g32 Section: Citation “https://doi.org/10.48329/52h1-8g32” Page: https://www.cprd.com/doi/cprd-primary-care-omop-common-data-model-march-2025	Response for Published referencesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Notes Recommended	CPRD data are drawn from UK GP practice systems and are widely used for epidemiology and pharmacoepidemiology. Data access is via CPRD governance and licensing processes.	Field-cited	HDR UK Gateway Collection: Clinical Practice Research Datalink (CPRD) https://www.healthdatagateway.org/en/collection/121 Section: Description “For more than 30 years, research using CPRD data and services has informed clinical guidance and best practice” Page: https://www.healthdatagateway.org/en/collection/121	Response for NotesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

3D cohort mapping

Consent, characterisation, and data availability axes used on the cohort map.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent level (axis) Required	2 — Section 251 / CAG (pseudonymised, no individual consent)	Field-cited	CPRD Data Access (RDG process) https://www.cprd.com/data-access Section: Data access “Access to CPRD data ... is subject to protocol approval via CPRD's Research Data Governance (RDG) Process.” Page: https://www.cprd.com/data-access Step 1: identifiable-at-source ecosystem YES (patient-level longitudinal records under controlled governance). Step 2: no individual research consent pathway described for each study, access is governance-based -> Level 2. Step 3/4 not reached. consent_level=2.	Response for Consent level (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Characterisation depth (axis) Required	1 — Routine EHR	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Abstract “The CPRD primary care database is therefore a rich source of health data for research, including data on demographics, symptoms, tests, diagnoses, therapies ...” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ Step 1 validated MH instruments? NO evidence of research-specific MH instruments as core cohort process (routine EHR coding). Therefore characterisation_depth=1.	Response for Characterisation depth (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data availability (axis) Required	1 — Clinical records only	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Flag derivation “routinely collected electronic health records” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ DERIVED per data-dictionary formula: hasResearch=FALSE; hasBiological=FALSE; hasAdvanced=FALSE; with has_linked_health_records=FALSE (CPRD is itself an EHR source, not a linked research cohort flag). Therefore data_availability=1.	Response for Data availability (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cohort map group (derived) Recommended	Group 4	Internal	Internal catalogue field	—	—
Population type Recommended	Data resource	Not published	DIGIT Cohort Portfolio Review — population type and engagement classification (Aug 2026) Classified data_resource in the DIGIT cohort portfolio review (Aug 2026). Anonymised national primary care records resource.	Response for Population typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Industry engagement status Recommended	Unknown	Not published	Searched — not published UNSOURCEABLE: industry engagement status is an organisational property of the custodian and is not publicly documented; default 'unknown' pending a cohort-owner meeting.	Response for Industry engagement statusAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Parent cohort / programme Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Parent cohort / programmeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TWiCs eligible Recommended	No	Not published	Searched — not published UNSOURCEABLE/derived FALSE: no evidence of active interventional broad participant consent model needed for TWiCs in core CPRD metadata.	Response for TWiCs eligibleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data modalities

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Questionnaire / interview Recommended	No	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Measures “Data from the CPRD ... originate from routine clinical practice” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ No core cohort-level validated research questionnaires collected by design -> FALSE.	Response for Questionnaire / interviewAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cognitive testing Recommended	No	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Measures “demographics, diagnoses, symptoms, signs, prescriptions, referrals, immunisations, behavioural factors, tests” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ No computerised cognitive testing modality listed -> FALSE.	Response for Cognitive testingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Physical measures Recommended	No	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Measures “Numerical data on additional clinical measures (e.g. height, weight, blood pressure, alcohol intake) can also be recorded during consultations.” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ These are routine care records, not dedicated research physical-measure collection in a cohort protocol. Conservative assignment FALSE per data-dictionary true-when rule.	Response for Physical measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosamples Recommended	No	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Abstract “ongoing primary care database of anonymised medical records” Page: https://doi.org/10.1093/ije/dyv098 No biosample bank described for CPRD core dataset -> FALSE.	Response for BiosamplesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genomic data Recommended	No	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Abstract “primary care database of anonymised medical records” Page: https://doi.org/10.1093/ije/dyv098 No cohort-wide genotyping/sequencing data modality declared in CPRD core profile -> FALSE.	Response for Genomic dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Omics Recommended	No	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Abstract “database of anonymised medical records” Page: https://doi.org/10.1093/ije/dyv098 No non-genomic omics layer declared in core CPRD profile -> FALSE.	Response for OmicsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging Recommended	No	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Abstract “rich source of health data ... demographics, symptoms, tests, diagnoses, therapies” Page: https://doi.org/10.1093/ije/dyv098 No research-grade imaging archive listed for core cohort -> FALSE.	Response for ImagingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Wearable / sensor Recommended	No	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Measures “routinely collected electronic health records” Page: https://doi.org/10.1093/ije/dyv098 No wearable device stream listed -> FALSE.	Response for Wearable / sensorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Digital phenotyping Recommended	No	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Measures “routinely recorded onto computers by practice staff” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ Routine coded EHR is not passive smartphone/sensor digital phenotyping per data dictionary -> FALSE.	Response for Digital phenotypingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked health records Recommended	No	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Data type rule application “The CPRD harnesses general practice data and produces a primary care dataset” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ Per data-dictionary FALSE-when rule: CPRD is itself a health-record dataset, not a research cohort linked outward under this boolean. Specific linkages are captured in has_nhs_linkage / has_death_registry_linkage.	Response for Linked health recordsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosample types Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: CPRD core metadata does not declare biosample banking for this cohort record.	Response for Biosample typesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genotyping platform Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no genomic platform field applicable for CPRD core dataset in reviewed pages.	Response for Genotyping platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging modalities Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no imaging modalities declared for CPRD core dataset.	Response for Imaging modalitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Mental health measures Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: CPRD is not centred on a named fixed mental health instrument battery.	Response for Mental health measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data subcategories

Structured modality and subcategory rows used alongside the high-level data-type flags.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Data subcategories Recommended List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.	No value held	No source yet	No citation linked to this field yet.	Response for Data subcategoriesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Data subcategories

Recommended

List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Consent and use permissions

Specific use permissions separate from the 3D consent-level axis.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent and use permissions Recommended Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.	No value held	No source yet	No citation linked to this field yet.	Response for Consent and use permissionsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Consent and use permissions

Recommended

Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Access pathways

One or more routes by which researchers can request or analyse data.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Access pathways Recommended Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.	No value held	No source yet	No citation linked to this field yet.	Response for Access pathwaysAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Access pathways

Recommended

Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Within-cohort coverage

Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Within-cohort coverage metrics Recommended Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.	No value held	No source yet	No citation linked to this field yet.	Response for Within-cohort coverage metricsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Within-cohort coverage metrics

Recommended

Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Linkage and access

Field	Current value	Evidence	Source evidence	Response	Notes / correction
NHS linkage Recommended	Yes	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Data linkage “Established linkages include Hospital Episode Statistics ... and Office for National Statistics (mortality data including causes of death).” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/	Response for NHS linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GP linkage Recommended	No	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Data resource basics “The CPRD harnesses general practice data and produces a primary care dataset” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ Set FALSE: GP data are native to CPRD (not externally linked GP feed) per linkage-field interpretation.	Response for GP linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Death registry linkage Recommended	Yes	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Data linkage “Established linkages include ... Office for National Statistics (mortality data including causes of death).” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/	Response for Death registry linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Education linkage Recommended	No	Not published	Searched — not published UNSOURCEABLE/assumed FALSE: reviewed linkage statements mention HES and mortality; no education linkage explicitly found.	Response for Education linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access mechanism Recommended	direct_application	Field-cited	CPRD Data Access (RDG process) https://www.cprd.com/data-access Section: Data access “Access to CPRD data ... is subject to protocol approval via CPRD's Research Data Governance (RDG) Process.” Page: https://www.cprd.com/data-access Access pathway is an application process to custodian -> direct_application.	Response for Data access mechanismAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TRE platform Recommended	CPRD Safe	Field-cited	CPRD Data Access (RDG process) https://www.cprd.com/data-access Section: Service context “All protocols must be submitted via eRAP.” Page: https://www.cprd.com/research-applications CPRD analysis environment referred to as CPRD Safe in access/pricing documentation; cohort field set to 'CPRD Safe'.	Response for TRE platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data dictionary URL Recommended	https://www.cprd.com/data	Field-cited	CPRD Official Website https://www.cprd.com/ Section: Data section “Data” Page: https://www.cprd.com/data	Response for Data dictionary URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access timeline (days) Recommended	No value held	Not published	Searched — not published UNSOURCEABLE as fixed numeric: CPRD states review feedback target of 4 weeks but full end-to-end access time remains variable.	Response for Data access timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access cost Recommended	From GBP 20,600 (single study licence, excl. VAT)	Field-cited	CPRD Pricing https://www.cprd.com/pricing Section: Single study dataset licence “Tier 2 £20,600 ... Tier 1 £83,850” Page: https://www.cprd.com/pricing Cohort field stores lowest listed single-study entry-point cost text.	Response for Data access costAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Participant profile and dates

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Age distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE for current 2025/2026 CPRD corpus in searched public pages. Historic 2013 age profile exists but not used as current distribution.	Response for Age distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Sex distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE for current 2025/2026 CPRD corpus in searched public pages. Historic representativeness analysis exists in 2015 profile only.	Response for Sex distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ethnicity distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE for current 2025/2026 CPRD corpus in searched public pages.	Response for Ethnicity distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Smoking status distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Smoking status distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Median age Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Current median age not published in the reviewed 2025/2026 source pages.	Response for Median ageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent female Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Current percentage female not published as a single up-to-date value in reviewed 2025/2026 pages.	Response for Percent femaleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent non-white Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Current percentage non-white not published as a single up-to-date value in reviewed public pages.	Response for Percent non-whiteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	national	Field-cited	HDR UK Gateway Collection: Clinical Practice Research Datalink (CPRD) https://www.healthdatagateway.org/en/collection/121 Section: Description “CPRD collects anonymised patient data from a network of GP practices across the UK.” Page: https://www.healthdatagateway.org/en/collection/121 UK-wide network -> national.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Follow-up duration Recommended	No value held	Not published	Searched — not published UNSOURCEABLE as single cohort-wide scalar: public pages provide variable follow-up across patients rather than one canonical duration bucket.	Response for Follow-up durationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Last data collection date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE as cohort-level date field: release pages give dataset coverage windows that vary by version and product.	Response for Last data collection dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment start date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE as participant recruitment date field; CPRD is a continuously operating data service.	Response for Recruitment start dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment end date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE as participant recruitment end date; service remains ongoing.	Response for Recruitment end dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis areas

Mental health diagnosis areas represented in this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis area: Schizophrenia Recommended Confirm this diagnosis area applies and estimated N if shown.	Schizophrenia · Psychotic Disorders	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Measures “clinical events (symptoms, diagnoses)” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ Schizophrenia coverage supported at diagnosis-record level. Existing row retained; estimated_n cleared to NULL due no verifiable count in reviewed source set.	Response for Diagnosis area: SchizophreniaAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Major depressive disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Major depressive disorder · Mood Disorders	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Measures “clinical events (symptoms, diagnoses)” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ Major depressive disorder coverage is plausible in CPRD coded diagnoses. Existing row retained; estimated_n cleared to NULL because no source-supported count in reviewed public materials.	Response for Diagnosis area: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Generalised anxiety disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Generalised anxiety disorder · Anxiety Disorders	Field-cited	Herrett et al. Data Resource Profile: CPRD (IJE 2015) https://doi.org/10.1093/ije/dyv098 Section: Measures “clinical events (symptoms, diagnoses)” Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/ Generalised anxiety disorder coverage supported at diagnosis-record level. Existing row retained; estimated_n cleared to NULL due no verifiable count in public source set.	Response for Diagnosis area: Generalised anxiety disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Diagnosis area: Schizophrenia

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Schizophrenia · Psychotic Disorders

Field-cited

Herrett et al. Data Resource Profile: CPRD (IJE 2015)
https://doi.org/10.1093/ije/dyv098
Section: Measures
“clinical events (symptoms, diagnoses)”
Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/
Schizophrenia coverage supported at diagnosis-record level. Existing row retained; estimated_n cleared to NULL due no verifiable count in reviewed source set.

AccurateNeeds correctionNot sureDoes not apply

Diagnosis area: Major depressive disorder

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Major depressive disorder · Mood Disorders

Field-cited

Herrett et al. Data Resource Profile: CPRD (IJE 2015)
https://doi.org/10.1093/ije/dyv098
Section: Measures
“clinical events (symptoms, diagnoses)”
Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/
Major depressive disorder coverage is plausible in CPRD coded diagnoses. Existing row retained; estimated_n cleared to NULL because no source-supported count in reviewed public materials.

AccurateNeeds correctionNot sureDoes not apply

Diagnosis area: Generalised anxiety disorder

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Generalised anxiety disorder · Anxiety Disorders

Field-cited

Herrett et al. Data Resource Profile: CPRD (IJE 2015)
https://doi.org/10.1093/ije/dyv098
Section: Measures
“clinical events (symptoms, diagnoses)”
Page: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521131/
Generalised anxiety disorder coverage supported at diagnosis-record level. Existing row retained; estimated_n cleared to NULL due no verifiable count in public source set.

AccurateNeeds correctionNot sureDoes not apply

Linked sites

Sites contributing participants or data to this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked sites Optional	No value held	No source yet	No citation linked to this field yet.	Response for Linked sitesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	unverified	Internal	Internal catalogue field	—	—
Last verified Recommended	No value held	Internal	Internal catalogue field	—	—
Data source Recommended	No value held	Internal	Internal catalogue field	—	—