Cohort validation pack

CRIS SLaM

Clinical Record Interactive Search (South London and Maudsley)

Generated 6 Oct 2026, 10:36 · ID 22

AI inferred

Instructions for reviewers

Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Summary of how well fields in this pack are linked to evidence.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	43 of 72 reviewable fields are cited to a source (60%) · 7 with no source yet · 22 searched — not published · 27 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and ownership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Short name Required	CRIS SLaM	Field-cited	CRIS SLaM — NIHR Maudsley BRC facility page https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ Section: Page title “Clinical Record Interactive Search (CRIS)” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Full name Required	Clinical Record Interactive Search (South London and Maudsley)	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: ArticleTitle “The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) case register: development and descriptive data.” Page: https://doi.org/10.1186/1471-244X-9-51	Response for Full nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Managing organisation Recommended	South London and Maudsley NHS Foundation Trust / King's College London	Field-cited	CRIS SLaM — NIHR Maudsley BRC facility page https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ Section: Footer / hosting “The NIHR Maudsley Biomedical Research Centre (BRC) is part of the NIHR and hosted by South London and Maudsley NHS Foundation Trust in partnership with King's College London.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/	Response for Managing organisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Primary site Recommended	NIHR Maudsley Biomedical Research Centre (site #1)	Field-cited	CRIS SLaM — NIHR Maudsley BRC facility page https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ Section: What is CRIS? “The Clinical Record Interactive Search (CRIS) system is a computer system that allows researchers at the NIHR Maudsley Biomedical Research Centre (BRC) to carry out research using information from South London and Maudsley NHS Foundation Trust clinical records.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ primary_site_id=1 (NIHR Maudsley BRC) is the NIHR BRC that operates CRIS for SLaM.	Response for Primary siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/	Field-cited	CRIS SLaM — NIHR Maudsley BRC facility page https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ Section: Canonical URL “N/A” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ website_url matches the NIHR Maudsley BRC CRIS facility page used as primary custodian documentation.	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catalogue of Mental Health Measures URL Recommended	https://www.cataloguementalhealth.ac.uk/CRIS	Field-cited	Catalogue of Mental Health Measures https://www.cataloguementalhealth.ac.uk Section: Official sitemap study URL “https://www.cataloguementalhealth.ac.uk/CRIS” Page: https://www.cataloguementalhealth.ac.uk/CRIS	Response for Catalogue of Mental Health Measures URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact name Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No named single point-of-contact field required for the cohort row was extracted from the reviewed pages beyond generic CRIS team / administrator references embedded in linkage subpages.	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No single public cohort contact email for CRIS SLaM identified on the NIHR Maudsley BRC CRIS pages reviewed; applications are process-based (CRIS Oversight Committee) rather than a published mailbox in the extracted facility page body.	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Summary and status

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Description Required	De-identified research copy of South London and Maudsley NHS Foundation Trust electronic mental health records, hosted for approved researchers under patient-led governance (CRIS Oversight Committee). Structured fields and free text (including NLP-derived features) are available for secondary analysis; linkage to selected external datasets is documented on the custodian linkage pages.	Field-cited	HDR UK Innovation Gateway — SLaM CRIS dataset record https://healthdatagateway.org/en/dataset/199 Section: Documentation “Structured and text fields are represented, the latter enhanced through a range of natural language processing algorithms.” Page: https://healthdatagateway.org/en/dataset/199 CRIS SLaM — NIHR Maudsley BRC facility page https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ Section: What is CRIS? “CRIS is safe and secure, and patients' personal details cannot be accessed by researchers who use it.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ Description synthesises facility page (de-identified research use) with HDR UK Gateway documentation on structured/text fields and NLP.	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N Required	400,000	Field-cited	HDR UK Innovation Gateway — SLaM CRIS dataset record https://healthdatagateway.org/en/dataset/199 Section: Documentation “CRIS provides researcher access to a live de-identified copy of SLaM's electronic health record, currently representing over 400,000 mental health service users.” Page: https://healthdatagateway.org/en/dataset/199	Response for Total NAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N qualifier Recommended	approximate_cumulative	Field-cited	HDR UK Innovation Gateway — SLaM CRIS dataset record https://healthdatagateway.org/en/dataset/199 Section: Documentation “currently representing over 400,000 mental health service users” Page: https://healthdatagateway.org/en/dataset/199 total_n_qualifier=approximate_cumulative because the Gateway reports a round cumulative service-user count, not an exact audited census.	Response for Total N qualifierAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Year established Recommended	2008	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Abstract / Results “Descriptive data are presented for the Register database as of October 2008.” Page: https://doi.org/10.1186/1471-244X-9-51 Operational case register described in 2009 publication with October 2008 snapshot; year_established retained as 2008 (register live by that snapshot) consistent with prior seed.	Response for Year establishedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active cohort Recommended	Yes	Field-cited	ISRCTN https://isrctn.com Page: https://www.isrctn.com/ Mandatory ISRCTN sweep (playbook Step 2): website searched for CRIS SLaM / South London and Maudsley Clinical Record Interactive Search as an ISRCTN-registered study dataset; no entry defines CRIS as a standalone ISRCTN trial cohort. is_active remains TRUE because custodian documentation describes an ongoing operational research system (see primary website provenance). CRIS SLaM — NIHR Maudsley BRC facility page https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ Section: What is CRIS? “The Clinical Record Interactive Search (CRIS) system is a computer system that allows researchers at the NIHR Maudsley Biomedical Research Centre (BRC) to carry out research using information from South London and Maudsley NHS Foundation Trust clinical records.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ Present-tense live system description on custodian page → is_active TRUE.	Response for Active cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ongoing recruitment Recommended	No	Field-cited	ClinicalTrials.gov https://clinicaltrials.gov Page: https://clinicaltrials.gov ongoing_recruitment=FALSE: CRIS is an electronic health record research database, not a single open-recruitment cohort protocol; ClinicalTrials.gov spot-check (API v2; queries including South London and Maudsley) lists interventional trials at the Trust/KCL but does not establish CRIS itself as an actively recruiting cohort study.	Response for Ongoing recruitmentAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Refreshed cohort Recommended	No	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Abstract “allowing in-depth secondary analysis of both numerical, string and free text data, whilst preserving anonymity through technical and procedural safeguards.” Page: https://doi.org/10.1186/1471-244X-9-51 No documentation of a prospective cohort refreshment wave separate from live EHR updates; is_refreshed=FALSE.	Response for Refreshed cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recontact success rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Not applicable / not published as a cohort recontact statistic for the CRIS EHR resource in the sources reviewed.	Response for Recontact success rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Retention rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Not applicable as a longitudinal cohort retention metric for the CRIS register resource in the sources reviewed.	Response for Retention rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Published references Recommended	doi:10.1186/1471-244X-9-51	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Citation “10.1186/1471-244X-9-51” Page: https://doi.org/10.1186/1471-244X-9-51	Response for Published referencesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Notes Recommended	Original CRIS implementation. HDR UK Gateway (2024) reports the live de-identified resource as representing over 400,000 mental health service users, with record coverage from 1970. Part of the wider CRIS Network of trust-level implementations.	No source yet	No citation linked to this field yet.	Response for NotesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

3D cohort mapping

Consent, characterisation, and data availability axes used on the cohort map.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent level (axis) Required	2 — Section 251 / CAG (pseudonymised, no individual consent)	Field-cited	CRIS Data Linkages — NIHR Maudsley BRC https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/ Section: Hospital Episode Statistics (HES) and Office for National Statistics (ONS) Mortality “This linkage is legally permissible under the Health Research Authority's support under Section 251 of the NHS Act 2006.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/ Step 1: Individual-level clinical records exist within the Trust (YES). Step 2: HRA Section 251 support is explicitly documented for linkage workflows (YES → consent_level 2 per data-dictionary). Steps 3–4 not met for cohort-wide prospective recontact/interventional consent.	Response for Consent level (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Characterisation depth (axis) Required	1 — Routine EHR	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Abstract / Methods “Descriptive data are presented for the Register database as of October 2008. The database at that point included 122,440 cases, 35,396 of whom were receiving active case management under the Care Programme Approach.” Page: https://doi.org/10.1186/1471-244X-9-51 Characterisation decision tree step 1: data derive from routine electronic clinical records and register-based ICD diagnoses (no research-protocol application of validated MH instruments described as the defining design). → characterisation_depth=1 (Routine EHR) per data-dictionary.	Response for Characterisation depth (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data availability (axis) Required	1 — Clinical records only	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Derivation “N/A — derived score” Page: https://doi.org/10.1186/1471-244X-9-51 Mechanical derivation: hasResearch = has_questionnaire_data OR has_cognitive_data OR has_physical_measures OR has_linked_health_records = FALSE; hasBiological=FALSE; hasAdvanced=FALSE → data_availability=1. has_linked_health_records is FALSE for this NHS EHR resource per data-dictionary (the archive is health records, not linkage of a separate research archive to NHS records).	Response for Data availability (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cohort map group (derived) Recommended	Group 4	Internal	Internal catalogue field	—	—
Population type Recommended	Data resource	Not published	DIGIT Cohort Portfolio Review — population type and engagement classification (Aug 2026) Classified data_resource in the DIGIT cohort portfolio review (Aug 2026). De-identified EHR research database of a secondary mental healthcare population — a clinical records resource, not a recruited cohort.	Response for Population typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Industry engagement status Recommended	Unknown	Not published	Searched — not published UNSOURCEABLE: industry engagement status is an organisational property of the custodian and is not publicly documented; default 'unknown' pending a cohort-owner meeting.	Response for Industry engagement statusAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Parent cohort / programme Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Parent cohort / programmeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TWiCs eligible Recommended	No	Not published	twics_eligible=FALSE per schema definition (requires consent_level=4 and infrastructure for randomisation within cohort); this resource is consent_level=2.	Response for TWiCs eligibleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data modalities

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Questionnaire / interview Recommended	No	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Methods “We describe the development of the South London and Maudsley NHS Foundation Trust (SLAM) Biomedical Research Centre (BRC) Case Register Interactive Search tool (CRIS) which allows research-accessible datasets to be derived from SLAM, the largest provider of secondary mental healthcare in Europe.” Page: https://doi.org/10.1186/1471-244X-9-51 FALSE per data-dictionary: cohort profile describes a case register / EHR analysis system, not a named research battery of validated PROMs administered under a study protocol.	Response for Questionnaire / interviewAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cognitive testing Recommended	No	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Methods “All clinical data, including free text, are available for analysis in the form of anonymised datasets.” Page: https://doi.org/10.1186/1471-244X-9-51 FALSE: no evidence of research-grade cognitive test battery (e.g., CANTAB) as an archived research modality distinct from incidental clinical documentation.	Response for Cognitive testingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Physical measures Recommended	No	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Results “The most common assigned primary diagnoses were within the ICD mood disorders (n = 12,756) category followed by schizophrenia and related disorders (8158), substance misuse (7749), neuroses (7105) and organic disorders (6414).” Page: https://doi.org/10.1186/1471-244X-9-51 FALSE: paper reports ICD diagnoses from clinical records, not objective physical measurement programmes (anthropometry, spirometry, etc.) as a cohort-wide research resource.	Response for Physical measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosamples Recommended	No	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Abstract “allowing in-depth secondary analysis of both numerical, string and free text data, whilst preserving anonymity through technical and procedural safeguards.” Page: https://doi.org/10.1186/1471-244X-9-51 FALSE: no biobanking modality described in CRIS case register profile.	Response for BiosamplesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genomic data Recommended	No	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Abstract “allowing in-depth secondary analysis of both numerical, string and free text data, whilst preserving anonymity through technical and procedural safeguards.” Page: https://doi.org/10.1186/1471-244X-9-51 FALSE: no genotyping/sequencing archive described for CRIS register resource.	Response for Genomic dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Omics Recommended	No	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Abstract “allowing in-depth secondary analysis of both numerical, string and free text data, whilst preserving anonymity through technical and procedural safeguards.” Page: https://doi.org/10.1186/1471-244X-9-51 FALSE: no proteomics/transcriptomics/etc. as defining CRIS modalities in this source.	Response for OmicsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging Recommended	No	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Abstract “allowing in-depth secondary analysis of both numerical, string and free text data, whilst preserving anonymity through technical and procedural safeguards.” Page: https://doi.org/10.1186/1471-244X-9-51 FALSE: CRIS profile concerns clinical records, not research imaging archives.	Response for ImagingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Wearable / sensor Recommended	No	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Abstract “allowing in-depth secondary analysis of both numerical, string and free text data, whilst preserving anonymity through technical and procedural safeguards.” Page: https://doi.org/10.1186/1471-244X-9-51 FALSE: no wearable sensor programme described.	Response for Wearable / sensorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Digital phenotyping Recommended	No	Field-cited	HDR UK Innovation Gateway — SLaM CRIS dataset record https://healthdatagateway.org/en/dataset/199 Section: Documentation “Structured and text fields are represented, the latter enhanced through a range of natural language processing algorithms.” Page: https://healthdatagateway.org/en/dataset/199 FALSE per data-dictionary digital phenotyping definition (passive smartphone/sensor streams); NLP on clinical text is not digital phenotyping.	Response for Digital phenotypingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked health records Recommended	No	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Overlap resolution “N/A — dictionary rule” Page: https://doi.org/10.1186/1471-244X-9-51 FALSE per docs/data-dictionary.md: CRIS is an NHS EHR research copy; the dictionary explicitly states NHS datasets are not classified as has_linked_health_records (use has_nhs_linkage / has_gp_linkage / has_death_registry_linkage / has_education_linkage instead).	Response for Linked health recordsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosample types Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No biosample_types array evidenced for the CRIS register resource in the reviewed custodian documentation.	Response for Biosample typesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genotyping platform Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No genotyping platform documented for CRIS as an EHR resource in reviewed sources.	Response for Genotyping platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging modalities Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No imaging_modalities research archive documented for CRIS in reviewed sources.	Response for Imaging modalitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Mental health measures Recommended	No value held	Not published	Searched — not published UNSOURCEABLE as a curated TEXT[] list: sources describe routine clinical and NLP-derived fields but do not publish a stable enumerated list of named research instruments suitable for mental_health_measures[] without full-text mining.	Response for Mental health measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data subcategories

Structured modality and subcategory rows used alongside the high-level data-type flags.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Data subcategories Recommended List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.	No value held	No source yet	No citation linked to this field yet.	Response for Data subcategoriesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Data subcategories

Recommended

List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Consent and use permissions

Specific use permissions separate from the 3D consent-level axis.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent and use permissions Recommended Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.	No value held	No source yet	No citation linked to this field yet.	Response for Consent and use permissionsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Consent and use permissions

Recommended

Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Access pathways

One or more routes by which researchers can request or analyse data.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Access pathways Recommended Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.	No value held	No source yet	No citation linked to this field yet.	Response for Access pathwaysAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Access pathways

Recommended

Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Within-cohort coverage

Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Within-cohort coverage metrics Recommended Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.	No value held	No source yet	No citation linked to this field yet.	Response for Within-cohort coverage metricsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Within-cohort coverage metrics

Recommended

Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Linkage and access

Field	Current value	Evidence	Source evidence	Response	Notes / correction
NHS linkage Recommended	Yes	Field-cited	CRIS Data Linkages — NIHR Maudsley BRC https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/ Section: Hospital Episode Statistics (HES) and Office for National Statistics (ONS) Mortality “NHS England (formally NHS Digital) are the data controller for the Hospital Episode Statistics (HES) and Office for National Statistics (ONS) Mortality data.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/	Response for NHS linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GP linkage Recommended	Yes	Field-cited	CRIS Data Linkages — NIHR Maudsley BRC https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/ Section: Lambeth DataNet (LDN) “The CDLS has linked LDN to CRIS and currently hold anonymised LDN data for patients of the South London and Maudsley NHS Foundation Trust who are registered with a GP in Lambeth.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/	Response for GP linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Death registry linkage Recommended	Yes	Field-cited	CRIS Data Linkages — NIHR Maudsley BRC https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/ Section: Hospital Episode Statistics (HES) and Office for National Statistics (ONS) Mortality “The ONS collects information on date and cause of death from death certificates.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/	Response for Death registry linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Education linkage Recommended	Yes	Field-cited	CRIS Data Linkages — NIHR Maudsley BRC https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/ Section: National Pupil Database (NPD) “The CDLS holds anonymised data from the NPD linked with the South London and Maudsley NHS Foundation Trust (the Trust) Child and Adolescent Mental Health Service (CAMHS), as well as an anonymised control sample of all school aged children, who are not Trust service-users, who were at school and lived in Croydon, Lambeth, Lewisham or Southwark from 2007 to 2019.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/	Response for Education linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access mechanism Recommended	tre	Field-cited	CRIS Data Linkages — NIHR Maudsley BRC https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/ Section: What is Data Linkage? “TRE's have been set up in the NHS to ensure that confidential patient information can be linked in a way that guarantees the legal and ethical rights of patients.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/ data_access_mechanism=tre aligns with explicit Trusted Research Environment hosting described for CDLS linkages.	Response for Data access mechanismAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TRE platform Recommended	CRIS (within-SLaM secure environment; NIHR Maudsley BRC governance)	Field-cited	CRIS Data Linkages — NIHR Maudsley BRC https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/ Section: Data access “Data is hosted in the CDLS Trusted Research Environment (TRE) within the South London and Maudsley NHS Foundation Trust.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/cris-data-linkages/	Response for TRE platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data dictionary URL Recommended	https://healthdatagateway.org/en/dataset/199	Field-cited	HDR UK Innovation Gateway — SLaM CRIS dataset record https://healthdatagateway.org/en/dataset/199 Section: Gateway record “N/A — URL field” Page: https://healthdatagateway.org/en/dataset/199 data_dictionary_url points to the HDR UK Gateway dataset record as the public metadata hub for the resource.	Response for Data dictionary URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access timeline (days) Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: HDR UK Gateway lists access timing as Variable / pipeline not available for a single numeric timeline_days figure on 2026-04-15.	Response for Data access timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access cost Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No public tariff for CRIS access captured in the reviewed facility and Gateway pages.	Response for Data access costAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Participant profile and dates

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Age distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE for structured JSON: Stewart et al. 2009 notes gender/ethnic representativeness in narrative but does not publish an age_distribution object usable as JSONB; no HDR Gateway structured age table for this dataset entry was found on 2026-04-15.	Response for Age distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Sex distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE for structured JSON: paper states representativeness on gender but does not provide extractable distribution object for sex_distribution JSONB.	Response for Sex distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ethnicity distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE for structured JSON: paper states representativeness on ethnicity but does not provide extractable distribution object for ethnicity_distribution JSONB.	Response for Ethnicity distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Smoking status distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Smoking status distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Median age Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Stewart et al. 2009 abstract does not report median age as a scalar; HDR UK Gateway dataset page reviewed did not expose a median age field suitable for this column on 2026-04-15.	Response for Median ageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent female Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Gender representativeness is discussed narratively in Stewart et al. 2009 but a percent_female value is not extractable as a DECIMAL from the abstract/snapshot table without full-text table extraction.	Response for Percent femaleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent non-white Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Ethnicity representativeness is discussed narratively in Stewart et al. 2009 but percent_non_white is not extractable as a DECIMAL from the abstract without full-text table extraction.	Response for Percent non-whiteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	single_site	Field-cited	HDR UK Innovation Gateway — SLaM CRIS dataset record https://healthdatagateway.org/en/dataset/199 Section: Coverage “Geographic coverage: United Kingdom, England, London, Croydon, Lambeth, Lewisham, Southwark” Page: https://healthdatagateway.org/en/dataset/199 single_site chosen because the resource is bounded to one NHS provider trust catchment (multi-borough but single Trust legal entity), matching data-dictionary single_site definition.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Follow-up duration Recommended	EHR from 1970 (Gateway); live CRIS copy in Trust	Field-cited	HDR UK Innovation Gateway — SLaM CRIS dataset record https://healthdatagateway.org/en/dataset/199 Section: Coverage “Start date: 01/01/1970” Page: https://healthdatagateway.org/en/dataset/199 followup_duration string summarises long retrospective coverage from Gateway start date plus ongoing live database per custodian documentation.	Response for Follow-up durationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Last data collection date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Live EHR-backed resource without a single published last_data_collection_date suitable for this DATE column in reviewed metadata.	Response for Last data collection dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment start date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Administrative case register / live EHR resource — not a closed recruitment window cohort with a recruitment_start_date.	Response for Recruitment start dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment end date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Not applicable for this resource type.	Response for Recruitment end dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis areas

Mental health diagnosis areas represented in this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis area: Schizophrenia Recommended Confirm this diagnosis area applies and estimated N if shown.	Schizophrenia · Psychotic Disorders · est. n=8,158	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Results “The most common assigned primary diagnoses were within the ICD mood disorders (n = 12,756) category followed by schizophrenia and related disorders (8158), substance misuse (7749), neuroses (7105) and organic disorders (6414).” Page: https://doi.org/10.1186/1471-244X-9-51	Response for Diagnosis area: SchizophreniaAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Bipolar disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Bipolar disorder · Mood Disorders · est. n=3,000	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Results “The most common assigned primary diagnoses were within the ICD mood disorders (n = 12,756) category followed by schizophrenia and related disorders (8158), substance misuse (7749), neuroses (7105) and organic disorders (6414).” Page: https://doi.org/10.1186/1471-244X-9-51 Mood disorders total split between bipolar (id 4) and MDD (id 5) because the publication reports a single combined mood count; split is approximate and documented in cohort_diagnosis_areas.notes.	Response for Diagnosis area: Bipolar disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Major depressive disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Major depressive disorder · Mood Disorders · est. n=9,756	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Results “The most common assigned primary diagnoses were within the ICD mood disorders (n = 12,756) category followed by schizophrenia and related disorders (8158), substance misuse (7749), neuroses (7105) and organic disorders (6414).” Page: https://doi.org/10.1186/1471-244X-9-51 See paired provenance for diagnosis_area_id=4; remainder of 12,756 ascribed to MDD after approximate bipolar allocation.	Response for Diagnosis area: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Generalised anxiety disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Generalised anxiety disorder · Anxiety Disorders · est. n=7,105	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Results “The most common assigned primary diagnoses were within the ICD mood disorders (n = 12,756) category followed by schizophrenia and related disorders (8158), substance misuse (7749), neuroses (7105) and organic disorders (6414).” Page: https://doi.org/10.1186/1471-244X-9-51 neuroses count used as administrative proxy for anxiety disorders including GAD within ICD-coded register tabulations.	Response for Diagnosis area: Generalised anxiety disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Substance use disorders Recommended Confirm this diagnosis area applies and estimated N if shown.	Substance use disorders · Substance Use · est. n=7,749	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Results “substance misuse (7749)” Page: https://doi.org/10.1186/1471-244X-9-51	Response for Diagnosis area: Substance use disordersAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Dementia / neurodegeneration Recommended Confirm this diagnosis area applies and estimated N if shown.	Dementia / neurodegeneration · Neurodegenerative · est. n=6,414	Field-cited	Stewart R et al. 2009 — SLAM BRC Case Register / CRIS (BMC Psychiatry) https://doi.org/10.1186/1471-244X-9-51 Section: Results “organic disorders (6414)” Page: https://doi.org/10.1186/1471-244X-9-51 Mapped to diagnosis_area_id 20 (Dementia / neurodegeneration) as closest DIGIT diagnosis-area bucket for organic mental disorder ICD groupings in administrative data.	Response for Diagnosis area: Dementia / neurodegenerationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Linked sites

Sites contributing participants or data to this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked site: NIHR Maudsley Biomedical Research Centre Recommended	NIHR Maudsley Biomedical Research Centre · London	Field-cited	CRIS SLaM — NIHR Maudsley BRC facility page https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ Section: What is CRIS? “The Clinical Record Interactive Search (CRIS) system is a computer system that allows researchers at the NIHR Maudsley Biomedical Research Centre (BRC) to carry out research using information from South London and Maudsley NHS Foundation Trust clinical records.” Page: https://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/ cohort_sites row links cohort 22 to site_id=1 as the NIHR Maudsley BRC that operates CRIS for SLaM.	Response for Linked site: NIHR Maudsley Biomedical Research CentreAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	ai_inferred	Internal	Internal catalogue field	—	—
Last verified Recommended	No value held	Internal	Internal catalogue field	—	—
Data source Recommended	No value held	Internal	Internal catalogue field	—	—