Cohort validation pack

PROTECT

Platform for Research Online to investigate Genetics and Cognition in Ageing

Generated 6 Oct 2026, 10:36 · ID 16

AI inferred

Instructions for reviewers

Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Summary of how well fields in this pack are linked to evidence.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	45 of 68 reviewable fields are cited to a source (66%) · 8 with no source yet · 15 searched — not published · 23 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and ownership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Short name Required	PROTECT	Field-cited	PROTECT Study — Official Website https://www.protectstudy.org.uk/ Section: Homepage heading “The PROTECT Study” Page: https://www.protectstudy.org.uk/	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Full name Required	Platform for Research Online to investigate Genetics and Cognition in Ageing	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Title “PROTECT Study: Platform for Research Online to investigate Genetics and Cognition in Ageing” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT	Response for Full nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Managing organisation Recommended	University of Exeter / King's College London / South London and Maudsley NHS Foundation Trust	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: What is the purpose of the study? “The study is being led by the University of Exeter and run in partnership with King's College London and the South London and Maudsley NHS Foundation Trust.” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT	Response for Managing organisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Primary site Recommended	NIHR Exeter Biomedical Research Centre (site #7)	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Sponsor organisation “Sponsor organisation University of Exeter” Page: https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/a-longitudinal-study-of-cognition-in-people-over-50/ primary_site_id=7 (NIHR Exeter BRC) aligns with University of Exeter sponsorship/leadership for PROTECT.	Response for Primary siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://www.protectstudy.org.uk/	Field-cited	PROTECT Study — Official Website https://www.protectstudy.org.uk/ Section: Homepage URL “https://www.protectstudy.org.uk/” Page: https://www.protectstudy.org.uk/	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catalogue of Mental Health Measures URL Recommended	https://www.cataloguementalhealth.ac.uk/PROTECT	Field-cited	Catalogue of Mental Health Measures https://www.cataloguementalhealth.ac.uk Section: Official sitemap study URL “https://www.cataloguementalhealth.ac.uk/PROTECT” Page: https://www.cataloguementalhealth.ac.uk/PROTECT	Response for Catalogue of Mental Health Measures URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact name Recommended	Anne Corbett	Field-cited	HRA Research Summary — PROTECT https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/a-longitudinal-study-of-cognition-in-people-over-50/ Section: Research summary “Contact name Anne Corbett” Page: https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/a-longitudinal-study-of-cognition-in-people-over-50/	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	support.protect@exeter.ac.uk	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Study Helpline “Email: support.protect@exeter.ac.uk” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Summary and status

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Description Required	Online UK longitudinal ageing cohort. Adults aged 40+ complete annual cognitive assessments and health/lifestyle questionnaires, with optional GP-note linkage and DNA saliva sampling.	Field-cited	University of Exeter — PROTECT Study page https://medicine.exeter.ac.uk/clinical-biomedical/research/protect/ Section: What is the PROTECT Study? “The PROTECT Study is an exciting approach to ageing research. It aims to understand how the brain ages and how we might reduce the risk of dementia and mental health issues in later life.” Page: https://medicine.exeter.ac.uk/clinical-biomedical/research/protect/	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N Required	25,000	Field-cited	University of Exeter — PROTECT Study page https://medicine.exeter.ac.uk/clinical-biomedical/research/protect/ Section: PROTECT data for research “PROTECT has collated a database of cognitive and health data in 25,000 older adults since its launch in 2014.” Page: https://medicine.exeter.ac.uk/clinical-biomedical/research/protect/ Used 25,000 as best available current approximate enrolment; supersedes older DPUK baseline 14,000 and homepage target 50,000.	Response for Total NAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N qualifier Recommended	approximate	Field-cited	University of Exeter — PROTECT Study page https://medicine.exeter.ac.uk/clinical-biomedical/research/protect/ Section: PROTECT data for research “PROTECT has collated a database of cognitive and health data in 25,000 older adults since its launch in 2014.” Page: https://medicine.exeter.ac.uk/clinical-biomedical/research/protect/ Rounded published figure -> total_n_qualifier=approximate.	Response for Total N qualifierAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Year established Recommended	2014	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: Cohort Descriptives “Study start date ... 01/04/2014 00:00:00” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT	Response for Year establishedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active cohort Recommended	Yes	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: Cohort Descriptives “Is study ongoing? Yes” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT	Response for Active cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ongoing recruitment Recommended	Yes	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: Cohort Descriptives “Is study still recruiting? Yes” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT	Response for Ongoing recruitmentAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Refreshed cohort Recommended	Yes	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Annual follow-up “Each year we will contact you by email and/or SMS and ask you to repeat the cognitive assessments and to update your answers to the other questionnaires” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT	Response for Refreshed cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recontact success rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Recontact process is described but no cohort-wide response percentage is published in reviewed public sources.	Response for Recontact success rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Retention rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Annual follow-up is described but no retention percentage is publicly reported in reviewed sources.	Response for Retention rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Published references Recommended	10.48532/040000	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: DOI “Corbett, A. (2017). PROTECT [Data set]. Dementias Platform UK. https://doi.org/10.48532/040000” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT	Response for Published referencesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Notes Recommended	Approximate current cohort size is 25,000 participants with a long-term target of 50,000. Annual online follow-up over 25 years with dementia and mental-health-relevant measures.	Field-cited	University of Exeter — PROTECT Study page https://medicine.exeter.ac.uk/clinical-biomedical/research/protect/ Section: Portfolio + data scale “Over 60 collaborative projects that are using PROTECT data to conduct research into healthy ageing and cognition” Page: https://medicine.exeter.ac.uk/clinical-biomedical/research/protect/	Response for NotesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

3D cohort mapping

Consent, characterisation, and data availability axes used on the cohort map.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent level (axis) Required	3 — Broad consent (recontactable for future studies)	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Consent and recontact “You will be asked to sign the online study consent form on the website.” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT Step 1 identifiable=YES (consent form + personal details). Step 2 S251/CAG=NO (consent-based enrolment). Step 3 recontactable=YES ("You will be asked if you would like to be contacted about taking part in future research"). Step 4 specific interventional randomisation consent=NO (future studies require separate consent). -> consent_level 3.	Response for Consent level (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Characterisation depth (axis) Required	3 — Multi-domain MH characterisation	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Assessments “You will be asked to complete a series of online cognitive assessments, for example to test your memory, reasoning and attention.” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT Step 1 validated MH instruments YES (questionnaires include current mental health, depression, anxiety and alcohol use). Step 2 multi-domain assessment YES (cognition + lifestyle + medical history + mental health). Step 3 SCID/MINI/SCAN with refreshed cohort=NO explicit research-grade psychiatric interview evidence; annual refresh present. -> characterisation_depth 3.	Response for Characterisation depth (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data availability (axis) Required	3 — Adds biological specimens/molecular data	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Data modalities “You will be asked to complete a series of online cognitive assessments ... We will ask you to provide a saliva sample to allow us to have samples of your DNA for the study.” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT DERIVED per data-dictionary formula: hasResearch=TRUE (questionnaire/cognitive/physical/linkage flags). hasBiological=TRUE (biosamples/genomic). hasAdvanced=FALSE (no imaging/wearables/digital phenotyping). -> data_availability 3.	Response for Data availability (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cohort map group (derived) Recommended	Group 2	Internal	Internal catalogue field	—	—
Population type Recommended	General population	Not published	DIGIT Cohort Portfolio Review — population type and engagement classification (Aug 2026) Classified general_population in the DIGIT cohort portfolio review (Aug 2026). Online ageing cohort open to adults 40+ without diagnosis requirements.	Response for Population typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Industry engagement status Recommended	Unknown	Not published	Searched — not published UNSOURCEABLE: industry engagement status is an organisational property of the custodian and is not publicly documented; default 'unknown' pending a cohort-owner meeting.	Response for Industry engagement statusAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Parent cohort / programme Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Parent cohort / programmeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TWiCs eligible Recommended	No	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Future studies consent “you would receive details about the study and it would be your choice whether to take part or not ... You will be asked to complete a separate consent form for any additional study” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT Separate consent required for each new intervention; not active interventional blanket consent -> twics_eligible=FALSE.	Response for TWiCs eligibleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data modalities

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Questionnaire / interview Recommended	Yes	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Questionnaires “The mandatory questionnaires are ... A questionnaire about your current mental health, including depression, anxiety and alcohol use.” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT	Response for Questionnaire / interviewAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cognitive testing Recommended	Yes	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Assessments “You will be asked to complete a series of online cognitive assessments, for example to test your memory, reasoning and attention.” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT	Response for Cognitive testingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Physical measures Recommended	Yes	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: Physical Examination “BMI ... Weight (self-report, assessed before onset of dementia) ... Height (self-report, assessed before onset of dementia)” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT Physical measures are present (self-reported anthropometrics) -> TRUE per available source evidence.	Response for Physical measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosamples Recommended	Yes	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: DNA sample “We will ask you to provide a saliva sample to allow us to have samples of your DNA for the study.” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT	Response for BiosamplesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genomic data Recommended	Yes	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: Genomics “GWAS platform ... Y” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT	Response for Genomic dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Omics Recommended	No	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: Biosample/Genomics listing “GWAS platform” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT Genomics is documented; no separate non-genomic omics (proteomics/metabolomics/transcriptomics) stated -> FALSE.	Response for OmicsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging Recommended	No	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: Available variable groups “Digital Phenotyping ... Genomics ... Biosample Assays” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT No imaging modality section/evidence found in reviewed PROTECT sources -> FALSE.	Response for ImagingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Wearable / sensor Recommended	No	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: Available variable groups “Digital Phenotyping” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT No wearable sensor stream is documented in reviewed metadata -> FALSE.	Response for Wearable / sensorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Digital phenotyping Recommended	No	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: Digital Phenotyping table “Visual memory ... Reaction time ... Associative learning” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT These are active online cognitive tasks, not passive smartphone/sensor digital phenotyping per data-dictionary rules -> FALSE.	Response for Digital phenotypingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked health records Recommended	Yes	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Medical notes linkage “With your permission we will contact your GP to request a confidential copy of your medical notes.” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT	Response for Linked health recordsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosample types Recommended	saliva	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: DNA sample “We will ask you to provide a saliva sample” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT	Response for Biosample typesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genotyping platform Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Genotyping platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging modalities Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Imaging modalitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Mental health measures Recommended	AUDIT	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: Lifestyle table “Alcohol Use Disorders Identification Test (AUDIT)” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT	Response for Mental health measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data subcategories

Structured modality and subcategory rows used alongside the high-level data-type flags.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Data subcategories Recommended List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.	No value held	No source yet	No citation linked to this field yet.	Response for Data subcategoriesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Data subcategories

Recommended

List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Consent and use permissions

Specific use permissions separate from the 3D consent-level axis.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent and use permissions Recommended Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.	No value held	No source yet	No citation linked to this field yet.	Response for Consent and use permissionsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Consent and use permissions

Recommended

Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Access pathways

One or more routes by which researchers can request or analyse data.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Access pathways Recommended Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.	No value held	No source yet	No citation linked to this field yet.	Response for Access pathwaysAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Access pathways

Recommended

Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Within-cohort coverage

Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Within-cohort coverage metrics Recommended Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.	No value held	No source yet	No citation linked to this field yet.	Response for Within-cohort coverage metricsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Within-cohort coverage metrics

Recommended

Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Linkage and access

Field	Current value	Evidence	Source evidence	Response	Notes / correction
NHS linkage Recommended	No	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Linkage scope “With your permission we will contact your GP to request a confidential copy of your medical notes.” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT Evidence confirms GP linkage pathway but does not explicitly confirm broader NHS secondary-care linkage -> FALSE for has_nhs_linkage.	Response for NHS linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GP linkage Recommended	No	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Medical notes linkage “With your permission we will contact your GP to request a confidential copy of your medical notes.” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT	Response for GP linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Death registry linkage Recommended	No	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Data sharing scope “This information will only be used for the purpose of health and care research” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT No explicit ONS death-registry linkage statement found -> FALSE.	Response for Death registry linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Education linkage Recommended	No	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Study purpose “certain genes and lifestyle factors (such as exercise or education)” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT Education is collected as participant information, not administrative DfE linkage -> FALSE.	Response for Education linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access mechanism Recommended	direct_application	Field-cited	DPUK Data Portal — Apply For Cohort Data Access https://data.dpuk.ukserp.ac.uk/Apply Section: Apply For Cohort Data Access “any bona fide researcher can apply to access data from the DPUK cohort studies ... in a single application” Page: https://data.dpuk.ukserp.ac.uk/Apply Application-led process corresponds to data_access_mechanism=direct_application.	Response for Data access mechanismAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TRE platform Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No explicit named TRE platform is published for PROTECT in reviewed sources.	Response for TRE platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data dictionary URL Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No dedicated public PROTECT data dictionary URL was found; prior URL /researchers returned 404 at verification time.	Response for Data dictionary URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access timeline (days) Recommended	90	Field-cited	DPUK Data Portal — Apply For Cohort Data Access https://data.dpuk.ukserp.ac.uk/Apply Section: Apply For Cohort Data Access “gain access to your chosen data within 90 days” Page: https://data.dpuk.ukserp.ac.uk/Apply	Response for Data access timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access cost Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: DPUK application page describes process and timeline but no fixed cost is stated for PROTECT in reviewed pages.	Response for Data access costAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Participant profile and dates

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Age distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No public percentage age-band distribution found in sources reviewed (protectstudy.org.uk homepage, participant information sheet, Exeter page, DPUK cohort listing).	Response for Age distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Sex distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No public participant sex proportion table found in reviewed sources.	Response for Sex distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ethnicity distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Demographic variables listed as collected in DPUK metadata, but no published cohort ethnicity percentages found.	Response for Ethnicity distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Smoking status distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Smoking status distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Median age Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Eligible ages are published (40+ / 50+) but no cohort median age value is reported in reviewed sources.	Response for Median ageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent female Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No public female percentage located in reviewed sources.	Response for Percent femaleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent non-white Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No public ethnicity proportion table located in reviewed sources.	Response for Percent non-whiteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	national	Field-cited	PROTECT Study — Official Website https://www.protectstudy.org.uk/ Section: Who can participate? “Reside in UK” Page: https://www.protectstudy.org.uk/ UK-wide eligibility indicates national coverage.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Follow-up duration Recommended	25 years	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Study duration “people to join the study for the next 25 years” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT	Response for Follow-up durationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Last data collection date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Ongoing annual collection is described without a single last wave date in reviewed public sources.	Response for Last data collection dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment start date Recommended	1 Apr 2014	Field-cited	DPUK Cohort Directory — PROTECT https://doi.org/10.48532/040000 Section: Cohort Descriptives “Study start date ... 01/04/2014 00:00:00” Page: https://data.dpuk.ukserp.ac.uk/cohortdirectory/Item?fingerPrintID=PROTECT	Response for Recruitment start dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment end date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Study is still recruiting; no recruitment end date published in reviewed sources.	Response for Recruitment end dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis areas

Mental health diagnosis areas represented in this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis area: Dementia / neurodegeneration Recommended Confirm this diagnosis area applies and estimated N if shown.	Dementia / neurodegeneration · Neurodegenerative	Field-cited	PROTECT Study — Official Website https://www.protectstudy.org.uk/ Section: Eligibility “Do not have a diagnosis of dementia” Page: https://www.protectstudy.org.uk/ Cohort studies dementia risk/progression but does not publish confirmed dementia-case count in reviewed sources; estimated_n remains NULL. PROTECT Study — Official Website https://www.protectstudy.org.uk/ Section: Homepage purpose “It aims to understand how healthy brains age and why people develop dementia.” Page: https://www.protectstudy.org.uk/	Response for Diagnosis area: Dementia / neurodegenerationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Diagnosis area: Dementia / neurodegeneration

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Dementia / neurodegeneration · Neurodegenerative

Field-cited

PROTECT Study — Official Website
https://www.protectstudy.org.uk/
Section: Eligibility
“Do not have a diagnosis of dementia”
Page: https://www.protectstudy.org.uk/
Cohort studies dementia risk/progression but does not publish confirmed dementia-case count in reviewed sources; estimated_n remains NULL.
PROTECT Study — Official Website
https://www.protectstudy.org.uk/
Section: Homepage purpose
“It aims to understand how healthy brains age and why people develop dementia.”
Page: https://www.protectstudy.org.uk/

AccurateNeeds correctionNot sureDoes not apply

Linked sites

Sites contributing participants or data to this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked site: NIHR Maudsley Biomedical Research Centre Recommended	NIHR Maudsley Biomedical Research Centre · London	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Managing partnership “run in partnership with King's College London and the South London and Maudsley NHS Foundation Trust” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT Mapped to site_id=1 (NIHR Maudsley BRC; KCL/SLaM).	Response for Linked site: NIHR Maudsley Biomedical Research CentreAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked site: NIHR Exeter Biomedical Research Centre Recommended	NIHR Exeter Biomedical Research Centre · South West England	Field-cited	PROTECT Study Participant Information Sheet (v24) https://www.protectstudy.org.uk/Home/Pis/PROTECT Section: Lead institution “The study is being led by the University of Exeter” Page: https://www.protectstudy.org.uk/Home/Pis/PROTECT Mapped to site_id=7 (NIHR Exeter Biomedical Research Centre / University of Exeter lead).	Response for Linked site: NIHR Exeter Biomedical Research CentreAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	ai_inferred	Internal	Internal catalogue field	—	—
Last verified Recommended	No value held	Internal	Internal catalogue field	—	—
Data source Recommended	No value held	Internal	Internal catalogue field	—	—