Cohort validation pack

TEDS

Twins Early Development Study

Generated 6 Oct 2026, 10:36 · ID 13

Unverified

Instructions for reviewers

Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Summary of how well fields in this pack are linked to evidence.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	60 of 84 reviewable fields are cited to a source (71%) · 16 with no source yet · 8 searched — not published · 14 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and ownership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Short name Required	TEDS	Field-cited	TEDS — About TEDS https://www.teds.ac.uk/about-teds/ Section: About TEDS “The Twins Early Development Study is one of the foremost ongoing twin studies of its kind in the world.” Page: https://www.teds.ac.uk/about-teds/	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Full name Required	Twins Early Development Study	Field-cited	TEDS — About TEDS https://www.teds.ac.uk/about-teds/ Section: About TEDS “The Twins Early Development Study” Page: https://www.teds.ac.uk/about-teds/	Response for Full nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Managing organisation Recommended	King's College London	Field-cited	TEDS — About TEDS https://www.teds.ac.uk/about-teds/ Section: About TEDS “The study has been going since 1994 and is based at King's College London.” Page: https://www.teds.ac.uk/about-teds/	Response for Managing organisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Primary site Recommended	Institute of Psychiatry, Psychology & Neuroscience (site #13)	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Author information “Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK” Page: https://doi.org/10.1017/thg.2012.91 TEDS is run from the SGDP Centre within the IoPPN at KCL; primary site remains the IoPPN site record (id=13).	Response for Primary siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://www.teds.ac.uk/	Field-cited	TEDS — About TEDS https://www.teds.ac.uk/about-teds/ Section: About page URL “About TEDS” Page: https://www.teds.ac.uk/about-teds/	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catalogue of Mental Health Measures URL Recommended	https://www.cataloguementalhealth.ac.uk/TEDS	Field-cited	Catalogue of Mental Health Measures https://www.cataloguementalhealth.ac.uk Section: Official sitemap study URL “https://www.cataloguementalhealth.ac.uk/TEDS” Page: https://www.cataloguementalhealth.ac.uk/TEDS	Response for Catalogue of Mental Health Measures URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact name Recommended	Prof Thalia C. Eley	Field-cited	King's College London — TEDS study page https://www.kcl.ac.uk/research/teds-study Section: Study leadership “In 2021 Professor Thalia Eley took over as Director of TEDS.” Page: https://www.kcl.ac.uk/research/teds-study Current TEDS Director (also corroborated on the About TEDS page). General project contact remains teds-project@kcl.ac.uk.	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	teds-project@kcl.ac.uk	Field-cited	TEDS Medical Record Linkage https://www.teds.ac.uk/participants/medical-record-linkage/ Section: Medical Record Linkage FAQ “please let us know by emailing teds-project@kcl.ac.uk” Page: https://www.teds.ac.uk/participants/medical-record-linkage/	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Summary and status

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Description Required	Large UK longitudinal twin study following participants from infancy into adulthood, focused on cognitive, behavioural, and mental health development. More than 16,000 twin pairs born in England and Wales between 1994 and 1996 were recruited from national birth records, with data collected across 13 assessment waves from age 1 into the mid-twenties.	Field-cited	TEDS — About TEDS https://www.teds.ac.uk/about-teds/ Section: The Journey So Far “Using birth records of all twins born in England and Wales between 1994 and 1996, the parents of potential participants were contacted and the families invited to take part in the TEDS study.” Page: https://www.teds.ac.uk/about-teds/	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N Required	16,810	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Abstract “16,810 pairs of twins were originally enrolled in TEDS.” Page: https://doi.org/10.1017/thg.2012.91 Value is twin PAIRS / families recruited, not individuals — TEDS is counted in pairs. Stored as the approximate resource size. Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development From Infancy to Emerging Adulthood https://doi.org/10.1017/thg.2019.56 Section: Abstract + Recruitment “16,810 families expressed interest in taking part ... More than 10,000 of these families are still engaged in the study.” Page: https://doi.org/10.1017/thg.2019.56 Corroborates ~16,810 pairs/families recruited; >10,000 families remain active as of the 2019 profile.	Response for Total NAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N qualifier Recommended	approximate	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Abstract “16,810 pairs of twins were originally enrolled in TEDS.” Page: https://doi.org/10.1017/thg.2012.91 Recruitment/enrolment figure treated as approximate; live-participant counts are lower and reported as rounded numbers.	Response for Total N qualifierAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Year established Recommended	1994	Field-cited	TEDS — About TEDS https://www.teds.ac.uk/about-teds/ Section: About TEDS “The study has been going since 1994” Page: https://www.teds.ac.uk/about-teds/	Response for Year establishedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active cohort Recommended	Yes	Field-cited	TEDS — About TEDS https://www.teds.ac.uk/about-teds/ Section: The Journey So Far “more than 13,000 pairs remain involved to the present day.” Page: https://www.teds.ac.uk/about-teds/	Response for Active cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ongoing recruitment Recommended	No	No source yet	No citation linked to this field yet.	Response for Ongoing recruitmentAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Refreshed cohort Recommended	Yes	Field-cited	TEDS — Researchers https://www.teds.ac.uk/researchers/ Section: TEDS Research “Since then, we have collected data 13 times, at least once every two years.” Page: https://www.teds.ac.uk/researchers/	Response for Refreshed cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recontact success rate Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Recontact success rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Retention rate Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Retention rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Published references Recommended	doi:10.1017/thg.2019.56, doi:10.1017/thg.2012.91, doi:10.1002/jcv2.12154	Field-cited	Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties https://doi.org/10.1002/jcv2.12154 Section: Data description “Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties” Page: https://doi.org/10.1002/jcv2.12154 Required TEDS reference per data access policy; covers the most recent (mid-twenties, to age 26) data collection. Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development From Infancy to Emerging Adulthood https://doi.org/10.1017/thg.2019.56 Section: Cohort profile “Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development From Infancy to Emerging Adulthood” Page: https://doi.org/10.1017/thg.2019.56 Most recent full TEDS cohort profile; added to published_references. TEDS Data Access Policy https://www.teds.ac.uk/researchers/teds-data-access-policy/ Section: Citing TEDS “Trouton et al (2002) ... Oliver et al (2007) ... Haworth et al (2013) ... Rimfeld et al (2019) ... Lockhart et al (2023)” Page: https://www.teds.ac.uk/researchers/teds-data-access-policy/ Canonical TEDS reference set enumerated on the data access policy page.	Response for Published referencesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Notes Recommended	total_n is the count of twin pairs / families recruited (approx. 16,810), not individuals — TEDS is counted in pairs. More than 10,000 families remain actively involved (Rimfeld et al. 2019); the TEDS website cites more than 13,000 pairs still involved. Founded by Prof Robert Plomin and directed by Prof Thalia C. Eley since 2021. Managed collaboration-based data access requires the involvement of a core TEDS team member. The Environmental Risk (E-Risk) Longitudinal Twin Study follows a TEDS-derived subsample of 2,232 twins with deep mental-health phenotyping into adulthood; listed separately in the Catalogue of Mental Health Measures.	Field-cited	DIGIT Cohort Portfolio Review — population type and engagement classification (Aug 2026) Page: https://www.cataloguementalhealth.ac.uk/search CMHM screening: E-Risk follows a TEDS-derived subsample of 2,232 twins (CMHM study index, read 2026-08-09); folded as a note on TEDS. ClinicalTrials.gov search: Twins Early Development Study https://clinicaltrials.gov/search?term=%22Twins%20Early%20Development%20Study%22 Section: Registry search “0 studies” Page: https://clinicaltrials.gov/search?term=%22Twins%20Early%20Development%20Study%22 ClinicalTrials.gov API v2 searched 2026-07-16 for title "Twins Early Development Study": 0 studies returned. Consistent with TEDS being an observational cohort, not a registered interventional trial. ISRCTN was also checked; no interventional TEDS registration was found.	Response for NotesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

3D cohort mapping

Consent, characterisation, and data availability axes used on the cohort map.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent level (axis) Required	3 — Broad consent (recontactable for future studies)	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Consent description “Informed consent has been collected from the parents for each assessment, and informed assent was collected from the twins in adolescence.” Page: https://doi.org/10.1017/thg.2012.91 Step 1 identifiable=YES (consent/assent model). Step 2 S251=NO (participant-consent based). Step 3 recontactable=YES (13 repeated waves, ongoing involvement). Step 4 interventional-specific consent=NO. => consent_level 3.	Response for Consent level (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Characterisation depth (axis) Required	3 — Multi-domain MH characterisation	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Abstract + Measures “focus ... on cognitive and behavioral development ... collected questionnaire data on behavioral problems” Page: https://doi.org/10.1017/thg.2012.91 L1 routine-only=NO. L2 validated MH/questionnaire assessments=YES. L3 multi-domain (cognition + behavioural/health/environment)=YES. L4 research-grade psychiatric interview (SCID/MINI/SCAN)=NO (TEDS uses questionnaire/web measures, not clinical diagnostic interviews). => characterisation_depth 3.	Response for Characterisation depth (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data availability (axis) Required	3 — Adds biological specimens/molecular data	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Abstract + data flags “DNA has been collected ... genome-wide genotyping data ... we have also collected questionnaire data” Page: https://doi.org/10.1017/thg.2012.91 hasResearch=TRUE (questionnaire/cognitive), hasBiological=TRUE (biosamples/genomics), hasAdvanced=FALSE (no imaging/wearable/digital phenotyping). Formula => 3.	Response for Data availability (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cohort map group (derived) Recommended	Group 2	Internal	Internal catalogue field	—	—
Population type Recommended	General population	Not published	DIGIT Cohort Portfolio Review — population type and engagement classification (Aug 2026) Classified general_population in the DIGIT cohort portfolio review (Aug 2026). Twin birth cohort recruited from national birth records irrespective of health status.	Response for Population typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Industry engagement status Recommended	Not yet considered	Not published	DIGIT cohort-owner meetings — GLAD, REACH, TEDS (mid-2026) Cohort-owner meeting (2026): the study team had not considered clinical trials or industry access; no process exists.	Response for Industry engagement statusAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Parent cohort / programme Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Parent cohort / programmeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TWiCs eligible Recommended	No	No source yet	No citation linked to this field yet.	Response for TWiCs eligibleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data modalities

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Questionnaire / interview Recommended	Yes	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Measures “we have also collected questionnaire data on behavioral problems” Page: https://doi.org/10.1017/thg.2012.91	Response for Questionnaire / interviewAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cognitive testing Recommended	Yes	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Measures “Although cognition has been a major focus of TEDS” Page: https://doi.org/10.1017/thg.2012.91	Response for Cognitive testingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Physical measures Recommended	No	Not published	FALSE after source search: TEDS collects self-reported health/anthropometry via questionnaire; no cohort-wide objective measured physical measures (anthropometry/vitals/biochemistry) as defined in the DIGIT data dictionary are evidenced in reviewed sources.	Response for Physical measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosamples Recommended	Yes	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Abstract “DNA has been collected for more than 7,000 pairs” Page: https://doi.org/10.1017/thg.2012.91	Response for BiosamplesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genomic data Recommended	Yes	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Abstract “genome-wide genotyping data for two million DNA markers are available for 3,500 individuals” Page: https://doi.org/10.1017/thg.2012.91	Response for Genomic dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Omics Recommended	No	Not published	FALSE after source search: array genotyping is confirmed (see has_genomic_data) but no non-genomic omics dataset (methylation/proteomics/metabolomics) accessible to researchers is evidenced in reviewed public sources — worth confirming with cohort leads.	Response for OmicsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging Recommended	No	Not published	FALSE after source search: no brain/body imaging modality is mentioned in the TEDS About/Researchers pages, Haworth 2013, or Rimfeld 2019.	Response for ImagingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Wearable / sensor Recommended	No	Not published	FALSE after source search: no wearable/accelerometry sensor archive is evidenced. Age-21 smartphone-app collection is questionnaire/cognitive data delivered digitally, not wearable sensor data.	Response for Wearable / sensorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Digital phenotyping Recommended	No	Not published	FALSE after source search: app/web questionnaire collection is not passive digital phenotyping (GPS/screen-time/call metadata) under DIGIT rules.	Response for Digital phenotypingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked health records Recommended	No	Field-cited	TEDS Data Access Policy https://www.teds.ac.uk/researchers/teds-data-access-policy/ Section: Linked data “In future, we hope also to create links to NHS medical data.” Page: https://www.teds.ac.uk/researchers/teds-data-access-policy/ Data access policy still describes NHS health-record linkage as prospective; combined with the participant-facing Medical Record Linkage project (source 113004), linkage is in progress but not yet established or available to researchers. Set FALSE conservatively. TEDS Medical Record Linkage https://www.teds.ac.uk/participants/medical-record-linkage/ Section: Overview “Medical Record Linkage is an exciting new project which will enable TEDS to link your TEDS research data to your electronic NHS health records.” Page: https://www.teds.ac.uk/participants/medical-record-linkage/ As of 2026 an active opt-in NHS linkage project exists but is described in the future tense ("will enable"); health-record linkage is not yet an established, accessible dataset. Confirm current status with cohort leads.	Response for Linked health recordsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosample types Recommended	DNA	Field-cited	Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development From Infancy to Emerging Adulthood https://doi.org/10.1017/thg.2019.56 Section: DNA studies “DNA samples have been obtained from 12,500 individuals” Page: https://doi.org/10.1017/thg.2019.56 Banked material confirmed as extracted DNA; only DNA is confirmed as an accessible biosample type.	Response for Biosample typesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genotyping platform Recommended	Affymetrix GeneChip 6.0 and Illumina HumanOmniExpressExome (~12,500 individuals genotyped; 10,346 after QC)	Field-cited	Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development From Infancy to Emerging Adulthood https://doi.org/10.1017/thg.2019.56 Section: DNA studies “genotyped on one of two DNA microarrays (Affymetrix GeneChip 6.0 or Illumina HumanOmniExpressExome chips) ... the total sample size available for genomic analyses is 10,346” Page: https://doi.org/10.1017/thg.2019.56	Response for Genotyping platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging modalities Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Imaging modalitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Mental health measures Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Mental health measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data subcategories

Structured modality and subcategory rows used alongside the high-level data-type flags.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Data modality: DNA sample Recommended Confirm this row is correctly typed as a category marker, named instrument/interview, biospecimen type, assay/data product, imaging modality, sensor stream, or linked-record type; add missing named instruments/sample types where known.	available · biosamples · biospecimen type · parent: Biospecimen collection · DNA sample collection	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot modality classification “DNA sample collection” Structured modality row derived from existing sourced cohort modality flags and detail fields; confirm exact release status and availability with cohort owner.	Response for Data modality: DNA sampleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data modality: Biospecimen collection Recommended Confirm this row is correctly typed as a category marker, named instrument/interview, biospecimen type, assay/data product, imaging modality, sensor stream, or linked-record type; add missing named instruments/sample types where known.	available · biosamples · category marker · DNA collected for a participant subset	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot modality classification “DNA collected for a participant subset” Structured modality row derived from existing sourced cohort modality flags and detail fields; confirm exact release status and availability with cohort owner.	Response for Data modality: Biospecimen collectionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data modality: Cognitive assessment data Recommended Confirm this row is correctly typed as a category marker, named instrument/interview, biospecimen type, assay/data product, imaging modality, sensor stream, or linked-record type; add missing named instruments/sample types where known.	available · cognitive measures · category marker · Cognition has been a major TEDS focus	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot modality classification “Cognition has been a major TEDS focus” Structured modality row derived from existing sourced cohort modality flags and detail fields; confirm exact release status and availability with cohort owner.	Response for Data modality: Cognitive assessment dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data modality: Cognitive function measures Recommended Confirm this row is correctly typed as a category marker, named instrument/interview, biospecimen type, assay/data product, imaging modality, sensor stream, or linked-record type; add missing named instruments/sample types where known.	available · cognitive measures · cognitive assessment · parent: Cognitive assessment data · Cognitive-function measures collected across waves	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot modality classification “Cognitive-function measures collected across waves” Structured modality row derived from existing sourced cohort modality flags and detail fields; confirm exact release status and availability with cohort owner.	Response for Data modality: Cognitive function measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data modality: Genotyping array Recommended Confirm this row is correctly typed as a category marker, named instrument/interview, biospecimen type, assay/data product, imaging modality, sensor stream, or linked-record type; add missing named instruments/sample types where known.	available · genomics · derived genomic data · Genome-wide genotyping data for a participant subset	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot modality classification “Genome-wide genotyping data for a participant subset” Structured modality row derived from existing sourced cohort modality flags and detail fields; confirm exact release status and availability with cohort owner.	Response for Data modality: Genotyping arrayAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data modality: Questionnaire / interview data Recommended Confirm this row is correctly typed as a category marker, named instrument/interview, biospecimen type, assay/data product, imaging modality, sensor stream, or linked-record type; add missing named instruments/sample types where known.	available · questionnaires · category marker · Repeated questionnaires on behavioural, cognitive and mental health development	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot modality classification “Repeated questionnaires on behavioural, cognitive and mental health development” Structured modality row derived from existing sourced cohort modality flags and detail fields; confirm exact release status and availability with cohort owner.	Response for Data modality: Questionnaire / interview dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Consent and use permissions

Specific use permissions separate from the 3D consent-level axis.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent/use: Biosample research use Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ.	permitted · biosample use · local operational permission · Participants with DNA samples · DNA has been collected for a participant subset.	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot consent/use permission classification “DNA has been collected for a participant subset.” Structured consent/use row derived from existing sourced consent and access statements. Status captures whether the permission is explicit, restricted, or unknown in public sources.	Response for Consent/use: Biosample research useAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Consent/use: Industry / commercial research considered Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ.	unknown · commercial use · local operational permission · Approved collaborators · Industry/commercial use is not explicit in the current public seed source set.	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot consent/use permission classification “Industry/commercial use is not explicit in the current public seed source set.” Structured consent/use row derived from existing sourced consent and access statements. Status captures whether the permission is explicit, restricted, or unknown in public sources.	Response for Consent/use: Industry / commercial research consideredAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Consent/use: Health record linkage permitted Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ.	unknown · data linkage · local operational permission · Participants · NHS linkage is described as future intent in public policy text.	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot consent/use permission classification “NHS linkage is described as future intent in public policy text.” Structured consent/use row derived from existing sourced consent and access statements. Status captures whether the permission is explicit, restricted, or unknown in public sources.	Response for Consent/use: Health record linkage permittedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Consent/use: Data sharing permitted Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ.	restricted · data sharing · local operational permission · Approved collaborators · Access requires agreement and involvement of a core TEDS team member.	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot consent/use permission classification “Access requires agreement and involvement of a core TEDS team member.” Structured consent/use row derived from existing sourced consent and access statements. Status captures whether the permission is explicit, restricted, or unknown in public sources.	Response for Consent/use: Data sharing permittedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Consent/use: Collaboration required Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ.	restricted · governance · duo modifier · Approved collaborators · Access requires agreement and involvement of a core TEDS team member.	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot consent/use permission classification “Access requires agreement and involvement of a core TEDS team member.” Structured consent/use row derived from existing sourced consent and access statements. Status captures whether the permission is explicit, restricted, or unknown in public sources.	Response for Consent/use: Collaboration requiredAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Consent/use: Participant recontact permitted Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ.	permitted · recontact · local operational permission · Participating families / twins · Repeated waves and continuing involvement imply a recontactable cohort model.	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot consent/use permission classification “Repeated waves and continuing involvement imply a recontactable cohort model.” Structured consent/use row derived from existing sourced consent and access statements. Status captures whether the permission is explicit, restricted, or unknown in public sources.	Response for Consent/use: Participant recontact permittedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Consent/use: Health / medical / biomedical research use Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ.	permitted · research use · duo permission · DUO:0000002 · Approved collaborators · Access policy supports external researchers with core-team agreement.	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot consent/use permission classification “Access policy supports external researchers with core-team agreement.” Structured consent/use row derived from existing sourced consent and access statements. Status captures whether the permission is explicit, restricted, or unknown in public sources.	Response for Consent/use: Health / medical / biomedical research useAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Consent/use: Approach for trials permitted Recommended Confirm status, population scope, whether the permission is a DUO-style restriction/permission or a local operational permission, and whether academic and industry/commercial use differ.	unknown · trial approach · local operational permission · Participating families / twins · No trial-approach permission identified in public sources.	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Pilot consent/use permission classification “No trial-approach permission identified in public sources.” Structured consent/use row derived from existing sourced consent and access statements. Status captures whether the permission is explicit, restricted, or unknown in public sources.	Response for Consent/use: Approach for trials permittedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Access pathways

One or more routes by which researchers can request or analyse data.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Access pathway: Collaboration required Recommended Confirm route, access level, environment type, DAC review, collaboration, data sharing agreement, output checking, platform, timeline, cost, URL, and whether multiple routes are possible.	restricted · access level: custodian review · environment: secure download · DAC review required · collaboration required · data sharing agreement required · TEDS core team · https://www.teds.ac.uk/researchers/teds-data-access-policy/ · Data requests require agreement and involvement of a member of the core TEDS team.	Field-cited	TEDS Data Access Policy https://www.teds.ac.uk/researchers/teds-data-access-policy/ Section: Pilot data access pathway classification “Data requests require agreement and involvement of a member of the core TEDS team.” Structured access pathway row derived from existing sourced access mechanism, TRE, cost, and route fields.	Response for Access pathway: Collaboration requiredAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Access pathway: Managed access / DAC Recommended Confirm route, access level, environment type, DAC review, collaboration, data sharing agreement, output checking, platform, timeline, cost, URL, and whether multiple routes are possible.	restricted · access level: custodian review · environment: secure download · DAC review required · collaboration required · data sharing agreement required · TEDS data access process · https://www.teds.ac.uk/researchers/teds-data-access-policy/ · External access is managed under TEDS data access policy.	Field-cited	TEDS Data Access Policy https://www.teds.ac.uk/researchers/teds-data-access-policy/ Section: Pilot data access pathway classification “External access is managed under TEDS data access policy.” Structured access pathway row derived from existing sourced access mechanism, TRE, cost, and route fields.	Response for Access pathway: Managed access / DACAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Access pathway: Collaboration required

Recommended

Confirm route, access level, environment type, DAC review, collaboration, data sharing agreement, output checking, platform, timeline, cost, URL, and whether multiple routes are possible.

restricted · access level: custodian review · environment: secure download · DAC review required · collaboration required · data sharing agreement required · TEDS core team · https://www.teds.ac.uk/researchers/teds-data-access-policy/ · Data requests require agreement and involvement of a member of the core TEDS team.

Field-cited

TEDS Data Access Policy
https://www.teds.ac.uk/researchers/teds-data-access-policy/
Section: Pilot data access pathway classification
“Data requests require agreement and involvement of a member of the core TEDS team.”
Structured access pathway row derived from existing sourced access mechanism, TRE, cost, and route fields.

AccurateNeeds correctionNot sureDoes not apply

Access pathway: Managed access / DAC

Recommended

Confirm route, access level, environment type, DAC review, collaboration, data sharing agreement, output checking, platform, timeline, cost, URL, and whether multiple routes are possible.

restricted · access level: custodian review · environment: secure download · DAC review required · collaboration required · data sharing agreement required · TEDS data access process · https://www.teds.ac.uk/researchers/teds-data-access-policy/ · External access is managed under TEDS data access policy.

Field-cited

TEDS Data Access Policy
https://www.teds.ac.uk/researchers/teds-data-access-policy/
Section: Pilot data access pathway classification
“External access is managed under TEDS data access policy.”
Structured access pathway row derived from existing sourced access mechanism, TRE, cost, and route fields.

AccurateNeeds correctionNot sureDoes not apply

Within-cohort coverage

Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Coverage: DNA collected for twin pairs Recommended Confirm numerator, denominator, unit type, exactness qualifiers, denominator type, basis, as-of date/release, source wording, and whether the metric is marginal, joint, conditional, or a release total.	> 7,000 / 16,810 (41.64% indicative) · unit: twin pairs · denominator: total cohort · basis: collected · status: available · scope: marginal · source value: more than 7,000 twin pairs · Numerator is stored as a lower-bound count for discoverability.	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Abstract “DNA has been collected for more than 7,000 pairs” Page: https://doi.org/10.1017/thg.2012.91	Response for Coverage: DNA collected for twin pairsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Coverage: Genome-wide genotyping data Recommended Confirm numerator, denominator, unit type, exactness qualifiers, denominator type, basis, as-of date/release, source wording, and whether the metric is marginal, joint, conditional, or a release total.	3,500 · unit: participants · denominator: unknown · basis: available to researchers · status: available · scope: marginal · source value: 3,500 individuals · Count is individuals, while total_n is twin pairs; denominator deliberately left null.	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Abstract “genome-wide genotyping data for two million DNA markers are available for 3,500 individuals” Page: https://doi.org/10.1017/thg.2012.91	Response for Coverage: Genome-wide genotyping dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Coverage: DNA collected for twin pairs

Recommended

Confirm numerator, denominator, unit type, exactness qualifiers, denominator type, basis, as-of date/release, source wording, and whether the metric is marginal, joint, conditional, or a release total.

> 7,000 / 16,810 (41.64% indicative) · unit: twin pairs · denominator: total cohort · basis: collected · status: available · scope: marginal · source value: more than 7,000 twin pairs · Numerator is stored as a lower-bound count for discoverability.

Field-cited

Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood
https://doi.org/10.1017/thg.2012.91
Section: Abstract
“DNA has been collected for more than 7,000 pairs”
Page: https://doi.org/10.1017/thg.2012.91

AccurateNeeds correctionNot sureDoes not apply

Coverage: Genome-wide genotyping data

Recommended

3,500 · unit: participants · denominator: unknown · basis: available to researchers · status: available · scope: marginal · source value: 3,500 individuals · Count is individuals, while total_n is twin pairs; denominator deliberately left null.

Field-cited

Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood
https://doi.org/10.1017/thg.2012.91
Section: Abstract
“genome-wide genotyping data for two million DNA markers are available for 3,500 individuals”
Page: https://doi.org/10.1017/thg.2012.91

AccurateNeeds correctionNot sureDoes not apply

Linkage and access

Field	Current value	Evidence	Source evidence	Response	Notes / correction
NHS linkage Recommended	No	Field-cited	TEDS Data Access Policy https://www.teds.ac.uk/researchers/teds-data-access-policy/ Section: Linked data “In future, we hope also to create links to NHS medical data.” Page: https://www.teds.ac.uk/researchers/teds-data-access-policy/ No established NHS linkage yet; the Medical Record Linkage project is underway (source 113004) but not complete. Set FALSE conservatively.	Response for NHS linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GP linkage Recommended	No	No source yet	No citation linked to this field yet.	Response for GP linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Death registry linkage Recommended	No	No source yet	No citation linked to this field yet.	Response for Death registry linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Education linkage Recommended	Yes	Field-cited	Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development From Infancy to Emerging Adulthood https://doi.org/10.1017/thg.2019.56 Section: Educational achievement “For 12,533 twins who provided written consent in 2016, we obtained official NC results from age 7 to 18 from the National Pupil Database (NPD)” Page: https://doi.org/10.1017/thg.2019.56 Education linkage to the National Pupil Database is established (n=12,533 consented twins). Note: NPD-derived data cannot be shared externally per TEDS data access policy section 11.	Response for Education linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access mechanism Recommended	collaboration	Field-cited	TEDS Data Access Policy https://www.teds.ac.uk/researchers/teds-data-access-policy/ Section: Principles of access to TEDS data “The request is submitted with the agreement and involvement of a member of the core TEDS team” Page: https://www.teds.ac.uk/researchers/teds-data-access-policy/ Access model requires managed collaboration and approval, so mechanism is collaboration.	Response for Data access mechanismAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TRE platform Recommended	No value held	No source yet	No citation linked to this field yet.	Response for TRE platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data dictionary URL Recommended	https://datadictionary.teds.ac.uk/home.htm	Field-cited	TEDS — Researchers https://www.teds.ac.uk/researchers/ Section: TEDS Research “a full breakdown of the measures can be found in our data dictionary” Page: https://www.teds.ac.uk/researchers/ Data dictionary confirmed live at https://datadictionary.teds.ac.uk/home.htm (documents studies from first contact to the 26-year follow-up).	Response for Data dictionary URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access timeline (days) Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Data access timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access cost Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Data access costAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Participant profile and dates

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Age distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: no public age-band JSON distribution table was found across the TEDS About, Researchers, Data Access Policy, and cohort-profile pages searched during this verification pass. (TEDS is a single birth-cohort band, all twins born 1994-1996.)	Response for Age distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Sex distribution Recommended	male: 0.5; female: 0.5	Field-cited	Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development From Infancy to Emerging Adulthood https://doi.org/10.1017/thg.2019.56 Section: Table 1 (Full sample, first contact) “% Female ... 50.0” Page: https://doi.org/10.1017/thg.2019.56 Rimfeld 2019 Table 1 full-sample first-contact figure; sex ratio approx. 50/50.	Response for Sex distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ethnicity distribution Recommended	white: 0.917; non_white: 0.083	Field-cited	Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development From Infancy to Emerging Adulthood https://doi.org/10.1017/thg.2019.56 Section: Table 1 (Full sample, first contact) “% White ... 91.7” Page: https://doi.org/10.1017/thg.2019.56 non_white computed as 1 - 0.917 = 0.083. Reflects 1990s England and Wales birth demographics.	Response for Ethnicity distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Smoking status distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Smoking status distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Median age Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Median ageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent female Recommended	50.00	Field-cited	Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development From Infancy to Emerging Adulthood https://doi.org/10.1017/thg.2019.56 Section: Table 1 (Full sample, first contact) “% Female ... 50.0” Page: https://doi.org/10.1017/thg.2019.56	Response for Percent femaleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent non-white Recommended	8.30	Field-cited	Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development From Infancy to Emerging Adulthood https://doi.org/10.1017/thg.2019.56 Section: Table 1 (Full sample, first contact) “% White ... 91.7” Page: https://doi.org/10.1017/thg.2019.56 Computed non-white proportion = 8.3%.	Response for Percent non-whiteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	national	Field-cited	TEDS — Researchers https://www.teds.ac.uk/researchers/ Section: TEDS Research “born in England and Wales between 1994-1996” Page: https://www.teds.ac.uk/researchers/ Coded as national coverage across England and Wales.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Follow-up duration Recommended	30+ years (1994-present)	Field-cited	TEDS — About TEDS https://www.teds.ac.uk/about-teds/ Section: The Journey So Far “The study has been going since 1994” Page: https://www.teds.ac.uk/about-teds/ 1994 to present interpreted as 30+ years at verification date; Lockhart 2023 reports data from ages 1 to 26.	Response for Follow-up durationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Last data collection date Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Last data collection dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment start date Recommended	1 Jan 1994	Field-cited	TEDS — About TEDS https://www.teds.ac.uk/about-teds/ Section: The Journey So Far “born in England and Wales between 1994 and 1996” Page: https://www.teds.ac.uk/about-teds/ Start normalised to 1994-01-01.	Response for Recruitment start dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment end date Recommended	31 Dec 1996	Field-cited	TEDS — About TEDS https://www.teds.ac.uk/about-teds/ Section: The Journey So Far “born in England and Wales between 1994 and 1996” Page: https://www.teds.ac.uk/about-teds/ End normalised to 1996-12-31.	Response for Recruitment end dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis areas

Mental health diagnosis areas represented in this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis area: Major depressive disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Major depressive disorder · Mood Disorders	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Measures “behavioral problems, such as anxiety, depression ... and ... ADHD” Page: https://doi.org/10.1017/thg.2012.91 Depression (MDD) coverage confirmed via dimensional symptom measures; diagnosis-specific N not published (population symptom measures, not diagnosed cases) so estimated_n=NULL.	Response for Diagnosis area: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Generalised anxiety disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Generalised anxiety disorder · Anxiety Disorders	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Measures “behavioral problems, such as anxiety, depression ... and ... ADHD” Page: https://doi.org/10.1017/thg.2012.91 Anxiety (GAD area) coverage confirmed via dimensional symptom measures; diagnosis-specific N not published so estimated_n=NULL.	Response for Diagnosis area: Generalised anxiety disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: ADHD Recommended Confirm this diagnosis area applies and estimated N if shown.	ADHD · Neurodevelopmental	Field-cited	Twins Early Development Study (TEDS): A Genetically Sensitive Investigation of Cognitive and Behavioral Development From Childhood to Young Adulthood https://doi.org/10.1017/thg.2012.91 Section: Measures “attention-deficit hyperactivity disorder (ADHD)” Page: https://doi.org/10.1017/thg.2012.91 ADHD (hyperactivity/inattention) coverage confirmed; diagnosis-specific N not publicly reported so estimated_n=NULL.	Response for Diagnosis area: ADHDAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Autism spectrum conditions Recommended Confirm this diagnosis area applies and estimated N if shown.	Autism spectrum conditions · Neurodevelopmental	Field-cited	Twins Early Development Study: A Genetically Sensitive Investigation into Behavioral and Cognitive Development From Infancy to Emerging Adulthood https://doi.org/10.1017/thg.2019.56 Section: Mental health “There are also measures of less common behaviours including autistic symptoms” Page: https://doi.org/10.1017/thg.2019.56 Autism spectrum coverage confirmed — TEDS has extensive autistic-symptom measurement. Dimensional symptom measures, not diagnosed cases, so estimated_n=NULL.	Response for Diagnosis area: Autism spectrum conditionsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Linked sites

Sites contributing participants or data to this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked sites Optional	No value held	No source yet	No citation linked to this field yet.	Response for Linked sitesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	unverified	Internal	Internal catalogue field	—	—
Last verified Recommended	No value held	Internal	Internal catalogue field	—	—
Data source Recommended	Re-verified 2026-07-16 against teds.ac.uk (About, Researchers, Data Access Policy, Medical Record Linkage), KCL TEDS study page, Haworth et al. 2013 (PMC3817931), Rimfeld et al. 2019 (PMC7056571), and Lockhart et al. 2023 (PMC10519737); ClinicalTrials.gov API v2 returned 0 registered TEDS trials (observational cohort). Web-verified against primary sources; pending confirmation by TEDS cohort leads.	Internal	Internal catalogue field	—	—