Cohort validation pack

MHM-Mood

Mental Health Mission Mood Disorder Cohort Study

Generated 6 Oct 2026, 10:36 · ID 1

Unverified

Instructions for reviewers

Review each field against your knowledge of this cohort. Mark Accurate if the value is right, Needs correction if it is wrong or inaccurate (add notes), Not sure if you cannot verify it, or Does not apply if the field is not relevant.
Evidence shown is from our source registry. Fields marked No source yet hold values we could not yet pin to a document — those were AI-inferred and need your input most. Fields marked Searched — not published are ones we looked for and could not find publicly; the note lists where we checked.
Your selections and notes are kept in this browser tab only (not sent to the database). Print or save as PDF when finished, then return it to the DIGIT team.

Overview

Total fields

Field-cited

Whole-record source only

AI-inferred, no source yet

Searched — not published

No value held

Needs review

Source coverage

Summary of how well fields in this pack are linked to evidence.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Field-level source coverage Optional	43 of 69 reviewable fields are cited to a source (62%) · 8 with no source yet · 18 searched — not published · 24 with no value held	Computed	No citation linked to this field yet.	Response for Field-level source coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Identity and ownership

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Short name Required	MHM-Mood	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: identificationModule.briefTitle “Mental Health Mission Mood Disorder Cohort Study” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Seed short label standardised to MHM-Mood for naming consistency while preserving official title in full_name.	Response for Short nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Full name Required	Mental Health Mission Mood Disorder Cohort Study	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: identificationModule.officialTitle “Mental Health Mission Mood Disorder Cohort Study” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Full nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Managing organisation Recommended	University of Oxford / NIHR MH-TRC Mission Mood Disorders Workstream	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: sponsorCollaboratorsModule.leadSponsor “"name":"University of Oxford"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Lead sponsor is University of Oxford; workstream governance contextualised via MH-TRC source.	Response for Managing organisationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Primary site Recommended	NIHR Oxford Health Biomedical Research Centre (site #2)	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: contactsLocationsModule.locations “"facility":"Clinical Research Facility, Warneford Hospital","city":"Oxford","country":"United Kingdom"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Mapped to site_id=2 (NIHR Oxford Health Biomedical Research Centre) as Oxford lead location.	Response for Primary siteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Website URL Recommended	https://oxfordhealthbrc.nihr.ac.uk/mh-trc/mood-disorders/	Field-cited	NIHR Oxford Health BRC — MH-TRC Mood Disorders Workstream https://oxfordhealthbrc.nihr.ac.uk/mh-trc/mood-disorders/ Section: Page heading “Mood Disorders – NIHR Oxford Health Biomedical Research Centre” Page: https://oxfordhealthbrc.nihr.ac.uk/mh-trc/mood-disorders/ Seed URL returned 404; replaced with active MH-TRC mood disorders workstream page.	Response for Website URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Catalogue of Mental Health Measures URL Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Catalogue of Mental Health Measures URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact name Recommended	Alexander Lewis	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: contactsLocationsModule.centralContacts “"name":"Alexander Lewis"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Contact nameAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Contact email Recommended	alexander.lewis@psych.ox.ac.uk	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: contactsLocationsModule.centralContacts “"email":"alexander.lewis@psych.ox.ac.uk"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Contact emailAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Summary and status

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Description Required	UK observational prospective cohort in adults with major depressive disorder or bipolar disorder under the NIHR MH-TRC Mission mood disorders network, designed for multi-domain profiling and future trial recontact.	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: descriptionModule.briefSummary “The current study aims to understand why some people with depression respond to treatment and others do not, using markers of clinical symptoms ... genomic ... metabolomic ... proteomic ... immune/inflammatory markers ...” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 CPFT Mood Disorders Research Clinic https://www.cpft.nhs.uk/moodclinic/ Section: Current research opportunities “This study aims to work over a long period with many different people with major depressive disorder or bipolar disorder, to deeply understand the clinical features and variations of these conditions and support long-term follow-up.” Page: https://www.cpft.nhs.uk/moodclinic/	Response for DescriptionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N Required	2,000	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: designModule.enrollmentInfo “"count":2000,"type":"ESTIMATED"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Total NAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Total N qualifier Recommended	target	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: designModule.enrollmentInfo “"count":2000,"type":"ESTIMATED"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Enrollment is a target estimate, so qualifier set to target.	Response for Total N qualifierAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Year established Recommended	2025	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: statusModule.studyFirstPostDateStruct “"date":"2025-09-24","type":"ACTUAL"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 First public registry posting and estimated start are in 2025, so year_established=2025.	Response for Year establishedAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Active cohort Recommended	Yes	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: statusModule.overallStatus “"overallStatus":"NOT_YET_RECRUITING"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Cohort is active in setup and listed on registry despite not yet recruiting.	Response for Active cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ongoing recruitment Recommended	No	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: statusModule.overallStatus “"overallStatus":"NOT_YET_RECRUITING"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Ongoing recruitmentAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Refreshed cohort Recommended	Yes	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: descriptionModule + outcomesModule “support long-term follow-up ... Up to 36 months.” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Refreshed cohortAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recontact success rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No published recontact response metric found across ClinicalTrials.gov, CPFT clinic page, or MH-TRC pages.	Response for Recontact success rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Retention rate Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No published retention percentage available for this newly listed cohort.	Response for Retention rateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Published references Recommended	NCT07189689	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: identificationModule.nctId “"nctId":"NCT07189689"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 No DOI-backed cohort profile found; registry identifier retained in published_references.	Response for Published referencesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Notes Recommended	ClinicalTrials.gov record NCT07189689 (posted Sep 2025) reports estimated enrollment 2,000, prospective follow-up up to 36 months, and UK multi-site support through the MH-TRC mood disorders network.	No source yet	No citation linked to this field yet.	Response for NotesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

3D cohort mapping

Consent, characterisation, and data availability axes used on the cohort map.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent level (axis) Required	3 — Broad consent (recontactable for future studies)	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: descriptionModule.briefSummary “Participants who provide consent for re-contact for future treatment trials and other research studies” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Step 1 identifiable=YES (consented participant cohort). Step 2 S251/CAG=NO (consent-based observational cohort). Step 3 recontactable=YES (quote). Step 4 specific interventional randomisation consent at enrollment=NO (future trial recontact, not pre-consented intervention). -> consent_level 3.	Response for Consent level (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Characterisation depth (axis) Required	3 — Multi-domain MH characterisation	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: descriptionModule + outcomesModule “clinical symptoms ... demographic information, cognitive function ... PHQ-9 ... GAD-7” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Step 1 validated MH instruments YES (PHQ-9, GAD-7). Step 2 multi-domain profiling YES (clinical + cognitive + biological). Step 3 research-grade SCID/MINI plus explicit refreshed interview protocol not shown; despite prospective follow-up, interview evidence is absent. -> characterisation_depth 3 (conservative).	Response for Characterisation depth (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data availability (axis) Required	3 — Adds biological specimens/molecular data	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: designModule + data flags “"bioSpecDescription":"DNA, RNA, serum, plasma and peripheral blood mononuclear cells (PBMC)"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 DERIVED per data-dictionary.md: hasResearch=TRUE (questionnaire + cognitive); hasBiological=TRUE (biosamples + genomic + omics); hasAdvanced=FALSE (no imaging/wearable/digital phenotyping evidence). Formula -> data_availability 3.	Response for Data availability (axis)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cohort map group (derived) Recommended	Group 2	Internal	Internal catalogue field	—	—
Population type Recommended	Clinical	Not published	DIGIT Cohort Portfolio Review — population type and engagement classification (Aug 2026) Classified clinical in the DIGIT cohort portfolio review (Aug 2026). Participants enter via the NIHR MH-TRC mood disorders network on MDD/bipolar diagnosis, enrolled for multi-domain profiling and future trial recontact.	Response for Population typeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Industry engagement status Recommended	Unknown	Not published	Searched — not published UNSOURCEABLE: industry engagement status is an organisational property of the custodian and is not publicly documented; default 'unknown' pending a cohort-owner meeting.	Response for Industry engagement statusAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Parent cohort / programme Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Parent cohort / programmeAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TWiCs eligible Recommended	No	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: consent wording “consent for re-contact for future treatment trials” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 TWiCs eligibility requires consent_level=4 in data dictionary; this cohort has broad recontact model (level 3), so FALSE.	Response for TWiCs eligibleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data modalities

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Questionnaire / interview Recommended	Yes	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: outcomesModule “PHQ-9 ... GAD-7” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Questionnaire / interviewAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Cognitive testing Recommended	Yes	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: descriptionModule.briefSummary “cognitive function” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Cognitive testingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Physical measures Recommended	No	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: descriptionModule.briefSummary “clinical symptoms ... demographic information ... cognitive function ... genomic ... metabolomic ... proteomic ... immune/inflammatory markers” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Objective anthropometry/vitals physical measures are not explicitly described; set FALSE conservatively per data dictionary.	Response for Physical measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosamples Recommended	Yes	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: designModule.bioSpec “"retention":"SAMPLES_WITH_DNA"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for BiosamplesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genomic data Recommended	Yes	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: descriptionModule.briefSummary “genetic sequence information (genomic)” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Genomic dataAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Omics Recommended	Yes	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: descriptionModule.briefSummary “chemical measures of metabolism (metabolomic), protein makeup (proteomic)” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for OmicsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging Recommended	No	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: registry summary “clinical symptoms ... cognitive function ... genomic ... metabolomic ... proteomic” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 No imaging modality stated in reviewed sources -> FALSE.	Response for ImagingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Wearable / sensor Recommended	No	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: registry summary “clinical symptoms ... cognitive function ... genomic ... metabolomic ... proteomic” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 No wearable sensor collection stated -> FALSE.	Response for Wearable / sensorAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Digital phenotyping Recommended	No	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: registry summary “clinical symptoms ... cognitive function ... genomic ... metabolomic ... proteomic” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 No passive smartphone or sensor-derived digital phenotyping described -> FALSE.	Response for Digital phenotypingAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Linked health records Recommended	No	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: studyPopulation “recruit adults aged 18 and over ... The study will be advertised on social media and will allow people to self-refer to the study. We will also recruit via GP mail outs.” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Recruitment via NHS pathways is described, but explicit linked-record dataset access is not; set FALSE conservatively.	Response for Linked health recordsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Biosample types Recommended	DNA, RNA, serum, plasma, PBMC	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: designModule.bioSpec.description “DNA, RNA, serum, plasma and peripheral blood mononuclear cells (PBMC)” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Biosample typesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Genotyping platform Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Source confirms genomic data but does not name specific array/sequencing platform.	Response for Genotyping platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Imaging modalities Recommended	No value held	Not published	Searched — not published UNSOURCEABLE/NOT APPLICABLE: has_imaging_data is FALSE in current public sources.	Response for Imaging modalitiesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Mental health measures Recommended	PHQ-9, GAD-7	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: outcomesModule “PHQ-9 ... GAD-7” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Mental health measuresAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Data subcategories

Structured modality and subcategory rows used alongside the high-level data-type flags.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Data subcategories Recommended List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.	No value held	No source yet	No citation linked to this field yet.	Response for Data subcategoriesAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Data subcategories

Recommended

List key data subcategories using distinct rows for category markers, named questionnaire/interview instruments, biospecimen types, omics/genomics data products, imaging modalities, sensor streams, and linked-record types.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Consent and use permissions

Specific use permissions separate from the 3D consent-level axis.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Consent and use permissions Recommended Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.	No value held	No source yet	No citation linked to this field yet.	Response for Consent and use permissionsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Consent and use permissions

Recommended

Confirm health/biomedical research use, industry/commercial consideration, non-commercial restrictions, governance modifiers, recontact, trial approach, biosample use, linkage, sharing, international transfer, and any Section 251/CAG support.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Access pathways

One or more routes by which researchers can request or analyse data.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Access pathways Recommended Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.	No value held	No source yet	No citation linked to this field yet.	Response for Access pathwaysAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Access pathways

Recommended

Confirm all data access pathways, including route, access level, TRE/SDE or download/API environment, DAC review, collaboration requirements, data sharing agreements, output checking, timelines, and fees.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Within-cohort coverage

Aggregate counts or percentages showing how broadly data, consent, or access characteristics apply within the cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Within-cohort coverage metrics Recommended Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.	No value held	No source yet	No citation linked to this field yet.	Response for Within-cohort coverage metricsAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Within-cohort coverage metrics

Recommended

Provide numerator, denominator, unit type, numerator/denominator exactness qualifiers, denominator type, basis, date/release, original source wording, and whether each metric is marginal, joint, conditional, or a release total.

No value held

No source yet

No citation linked to this field yet.

AccurateNeeds correctionNot sureDoes not apply

Linkage and access

Field	Current value	Evidence	Source evidence	Response	Notes / correction
NHS linkage Recommended	No	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: source_search_log “no explicit linked-record dataset access is described in public pages” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 FALSE by conservative rule until explicit NHS linkage statement is published.	Response for NHS linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
GP linkage Recommended	No	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: source_search_log “no explicit linked-record dataset access is described in public pages” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 FALSE by conservative rule until explicit GP linkage statement is published.	Response for GP linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Death registry linkage Recommended	No	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: source_search_log “no explicit linked-record dataset access is described in public pages” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 FALSE by conservative rule until explicit ONS linkage statement is published.	Response for Death registry linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Education linkage Recommended	No	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: source_search_log “no explicit linked-record dataset access is described in public pages” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 FALSE by conservative rule until explicit education linkage statement is published.	Response for Education linkageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access mechanism Recommended	collaboration	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: descriptionModule.briefSummary “This will allow future clinical trials within the NHS, academia and industry” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 No open self-service portal or TRE route published; participation appears collaboration-led through workstream clinics.	Response for Data access mechanismAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
TRE platform Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No TRE/SDE platform is named in reviewed public sources.	Response for TRE platformAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data dictionary URL Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No dedicated public data dictionary URL found in mandatory source sweep.	Response for Data dictionary URLAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access timeline (days) Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No numerical access timeline is published.	Response for Data access timeline (days)AccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Data access cost Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No public tariff/cost model is published.	Response for Data access costAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Participant profile and dates

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Age distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Public registry and workstream pages do not publish age-band proportions.	Response for Age distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Sex distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Public pages do not provide sex distribution percentages.	Response for Sex distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Ethnicity distribution Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Public pages do not provide ethnicity distribution percentages.	Response for Ethnicity distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Smoking status distribution Recommended	No value held	No source yet	No citation linked to this field yet.	Response for Smoking status distributionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Median age Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No median age published in accessed sources.	Response for Median ageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent female Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No sex proportion published in accessed sources.	Response for Percent femaleAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Percent non-white Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: No ethnicity proportion published in accessed sources.	Response for Percent non-whiteAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Geographic coverage Recommended	national	Field-cited	MH-TRC Review of 2025 Newsletter https://oxfordhealthbrc.nihr.ac.uk/mh-trc-newsletters/review-of-2025/ Section: Mood Disorders Cohort established “It is supported by 15 clinical academic sites across the UK” Page: https://oxfordhealthbrc.nihr.ac.uk/mh-trc-newsletters/review-of-2025/ UK-wide support across multiple sites -> geographic_coverage national.	Response for Geographic coverageAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Follow-up duration Recommended	Up to 36 months	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: outcomesModule.primaryOutcomes.timeFrame “Up to 36 months.” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Follow-up durationAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Last data collection date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Cohort is not yet recruiting; no last collection date exists.	Response for Last data collection dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment start date Recommended	1 Oct 2025	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: statusModule.startDateStruct “"date":"2025-10-01","type":"ESTIMATED"” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689	Response for Recruitment start dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Recruitment end date Recommended	No value held	Not published	Searched — not published UNSOURCEABLE: Registry does not expose a confirmed recruitment end date distinct from overall completion date.	Response for Recruitment end dateAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Diagnosis areas

Mental health diagnosis areas represented in this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Diagnosis area: Bipolar disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Bipolar disorder · Mood Disorders	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: conditionsModule.conditions “Depression Bipolar” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Mapped to Bipolar disorder diagnosis area id 4; subgroup n not published, so estimated_n remains NULL.	Response for Diagnosis area: Bipolar disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Major depressive disorder Recommended Confirm this diagnosis area applies and estimated N if shown.	Major depressive disorder · Mood Disorders	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: conditionsModule.conditions “Depression - Major Depressive Disorder” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Diagnosis area confirmed; diagnosis-specific subgroup n not published, so estimated_n remains NULL.	Response for Diagnosis area: Major depressive disorderAccurateNeeds correctionNot sureDoes not apply No response selected	No notes
Diagnosis area: Treatment-resistant depression Recommended Confirm this diagnosis area applies and estimated N if shown.	Treatment-resistant depression · Mood Disorders	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: conditionsModule.conditions “Treatment Resistant Depression” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 Diagnosis area confirmed; diagnosis-specific subgroup n not published, so estimated_n remains NULL.	Response for Diagnosis area: Treatment-resistant depressionAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Field

Current value

Evidence

Source evidence

Response

Notes / correction

Diagnosis area: Bipolar disorder

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Bipolar disorder · Mood Disorders

Field-cited

ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study
https://clinicaltrials.gov/api/v2/studies/NCT07189689
Section: conditionsModule.conditions
“Depression Bipolar”
Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689
Mapped to Bipolar disorder diagnosis area id 4; subgroup n not published, so estimated_n remains NULL.

AccurateNeeds correctionNot sureDoes not apply

Diagnosis area: Major depressive disorder

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Major depressive disorder · Mood Disorders

Field-cited

ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study
https://clinicaltrials.gov/api/v2/studies/NCT07189689
Section: conditionsModule.conditions
“Depression - Major Depressive Disorder”
Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689
Diagnosis area confirmed; diagnosis-specific subgroup n not published, so estimated_n remains NULL.

AccurateNeeds correctionNot sureDoes not apply

Diagnosis area: Treatment-resistant depression

Recommended

Confirm this diagnosis area applies and estimated N if shown.

Treatment-resistant depression · Mood Disorders

Field-cited

ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study
https://clinicaltrials.gov/api/v2/studies/NCT07189689
Section: conditionsModule.conditions
“Treatment Resistant Depression”
Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689
Diagnosis area confirmed; diagnosis-specific subgroup n not published, so estimated_n remains NULL.

AccurateNeeds correctionNot sureDoes not apply

Linked sites

Sites contributing participants or data to this cohort.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Linked site: NIHR Oxford Health Biomedical Research Centre Recommended	NIHR Oxford Health Biomedical Research Centre · South East England	Field-cited	ClinicalTrials.gov API — NCT07189689 Mental Health Mission Mood Disorder Cohort Study https://clinicaltrials.gov/api/v2/studies/NCT07189689 Section: contactsLocationsModule.locations “Clinical Research Facility, Warneford Hospital ... Oxford ... United Kingdom” Page: https://clinicaltrials.gov/api/v2/studies/NCT07189689 New cohort-site link added for Oxford lead location (site_id 2).	Response for Linked site: NIHR Oxford Health Biomedical Research CentreAccurateNeeds correctionNot sureDoes not apply No response selected	No notes

Verification metadata

Internal catalogue status — for reference only.

Field	Current value	Evidence	Source evidence	Response	Notes / correction
Verification status Recommended	unverified	Internal	Internal catalogue field	—	—
Last verified Recommended	No value held	Internal	Internal catalogue field	—	—
Data source Recommended	Verified Apr 2026 from ClinicalTrials.gov API record NCT07189689 plus MH-TRC mood disorder workstream pages (Oxford Health BRC and CPFT). Prior seed website URL returned 404 and was corrected.	Internal	Internal catalogue field	—	—